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USP48 encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Additionally we are shipping USP48 Antibodies (42) and many more products for this protein.
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Human USP48 Protein expressed in Wheat germ - ABIN1324823
Schweitzer, Naumann: CSN-associated USP48 confers stability to nuclear NF-?B/RelA by trimming K48-linked Ub-chains. in Biochimica et biophysica acta 2015
this study demonstrates that USP48 controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB (show NFKB1 Proteins)/RelA (show NFkBP65 Proteins) in the nucleus.
Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung.
The Overexpression of USP31 in HEK (show EPHA3 Proteins) 293T cells inhibited TNFalpha (show TNF Proteins), CD40 (show CD40 Proteins), LMP1 (show PDLIM7 Proteins), TRAF2 (show TRAF2 Proteins), TRAF6 (show TRAF6 Proteins) and IKKbeta (show IKBKB Proteins)-mediated NF-kappaB (show NFKB1 Proteins) activation, but did not inhibit Smad (show SMAD1 Proteins)-mediated transcription activation.
data demonstrate a crucial role for the dynamic interaction between D3R and USP48 in the regulation of NHE3 (show SLC9A3 Proteins) expression and function
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
ubiquitin specific peptidase 48
, ubiquitin specific protease 48
, ubiquitin specific peptidase 31
, ubiquitin carboxyl-terminal hydrolase 31-like
, ubiquitin carboxyl-terminal hydrolase 48-like
, deubiquitinating enzyme 48
, ubiquitin carboxyl-terminal hydrolase 48
, ubiquitin specific protease 31
, ubiquitin thioesterase 48
, ubiquitin thiolesterase 48
, ubiquitin-specific-processing protease 48
, synaptic ubiquitin-specific protease