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anti-Ubiquitin Specific Peptidase 5 (USP5) Antibodies

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. Additionally we are shipping USP5 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP5 8078 P45974
USP5 22225 P56399
USP5 297593  
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Top anti-USP5 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-USP5 Antibody (N-term) (ABIN1882150) in A2058 cell line lysates (35 µg/lane). USP5(arrow) was detected using the purified Pab. Western blot analysis of anti-USP5 Antibody (N-term) (ABIN1882150) in A2058 cell line lysates (35 µg/lane). USP5(arrow) was detected using the purified Pab. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB The anti-USP5 Pab (ABIN388886) is used in Western blot to detect USP5 in HL-60 cell lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded TOV-112D xenograft, using USP5, antibody at 1:500 dilution. WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 5 to 7 Days
$477.75
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY USP5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-USP5. Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-USP5 mouse monoclonal antibody. (ABIN2453776, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-USP5 mouse monoclonal antibody. (ABIN2453777, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-USP5 mouse monoclonal antibody. (ABIN2453777, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details

USP5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Top referenced anti-USP5 Antibodies

  1. Human Polyclonal USP5 Primary Antibody for IHC (p), WB - ABIN1882150 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 6 references for ABIN1882150

  2. Human Polyclonal USP5 Primary Antibody for EIA, WB - ABIN357529 : Ansari-Lari, Muzny, Lu, Lu, Lilley, Spanos, Malley, Gibbs: A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13. in Genome research 1996 (PubMed)
    Show all 4 references for ABIN357529

  3. Human Monoclonal USP5 Primary Antibody for WB - ABIN1944895 : Falquet, Paquet, Frutiger, Hughes, Hoang-Van, Jaton: cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2). in FEBS letters 1996 (PubMed)
    Show all 3 references for ABIN1944895

  4. Human Polyclonal USP5 Primary Antibody for IP, WB - ABIN262235 : Reverdy, Conrath, Lopez, Planquette, Atmanene, Collura, Harpon, Battaglia, Vivat, Sippl, Colland: Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. in Chemistry & biology 2012 (PubMed)

More Antibodies against USP5 Interaction Partners

Human Ubiquitin Specific Peptidase 5 (USP5) interaction partners

  1. A ubiquitin shuttle DC-UbP reconciles protein ubiquitination and deubiquitination via linking UbE1 (show UBA1 Antibodies) and USP5 enzymes.

  2. Used IM-MS analysis to study conformational flexibility of the multidomain deubiquitinating enzyme ubiquitin specific protease 5 (USP5).

  3. Charge-state distribution and ion mobility analysis revealed that both mono- and tetra-ubiquitin bound to the compact conformation of USP5 only.

  4. Cellular isopeptidase T deubiquitinating enzyme disassembles free ubiquitin chains to facilitate KSHV K7 degradation.

  5. polyubiquitin (show UBB Antibodies) chains by USP5 at sites of damage is important for efficient DSB repair

  6. Local administration of NO may prevent neointimal hyperplasia by inhibiting isopeptidase T levels and activity in the vasculature, thereby inhibiting the 26S proteasome (show Psmd4 Antibodies) in vascular smooth muscle cells.

  7. Production of the USP5 isoform 2 was strongly correlated with PTBP1 (show PTBP1 Antibodies) expression in glioblastoma tumor samples and cell lines.

  8. USP5 uses multiple zinc fluoride (ZnF)-ubiquitin binding protein (UBP (show SGTA Antibodies)) domains for substrate targeting and core catalytic function.

  9. Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain (show PSMA5 Antibodies) and isopeptidase T in fetal Down syndrome.

  10. We report the crystal structures of the zinc-finger ubiquitin binding domain (ZnF UBP (show SGTA Antibodies)) from the deubiquitinating enzyme isopeptidase T (IsoT, or USP5) alone and in complex with ubiquitin. This domain is required for optimal catalytic activation of IsoT.

Mouse (Murine) Ubiquitin Specific Peptidase 5 (USP5) interaction partners

  1. Suramin and Cav3.2 (show CACNA1H Antibodies)/USP5 Tat (show TAT Antibodies)-disruptor peptides were also tested in models of diabetic neuropathy and visceral pain, and provided remarkable protection

  2. Knockdown and overexpression studies demonstrated that Usp5 regulates p53 (show TP53 Antibodies) (and p73 (show ARHGAP24 Antibodies)) levels and alters cell growth and cell cycle distribution associated with p21 (show D4S234E Antibodies) induction.

  3. Local administration of NO may prevent neointimal hyperplasia by inhibiting isopeptidase T levels and activity in the vasculature, thereby inhibiting the 26S proteasome (show Psmd4 Antibodies) in vascular smooth muscle cells.

USP5 Antigen Profile

Protein Summary

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995

Gene names and symbols associated with USP5

  • ubiquitin specific peptidase 5 (isopeptidase T) (USP5) antibody
  • ubiquitin carboxyl-terminal hydrolase 5 (CNH02890) antibody
  • ubiquitin carboxyl-terminal hydrolase 5 (EHI_049940) antibody
  • ubiquitin carboxyl-terminal hydrolase 5 (CC1G_12961) antibody
  • ubiquitin carboxyl-terminal hydrolase 5 (MCYG_01862) antibody
  • ubiquitin carboxyl-terminal hydrolase 5 (CGB_L3600C) antibody
  • ubiquitin specific protease 5 (PY00546) antibody
  • ubiquitin specific peptidase 5 (LOC100347902) antibody
  • ubiquitin specific peptidase 5 (isopeptidase T) (Usp5) antibody
  • AA407472 antibody
  • ISOT antibody
  • ISOT-1 antibody
  • Ucht antibody

Protein level used designations for USP5

ubiquitin carboxyl-terminal hydrolase 5 , Ubiquitin isopeptidase T , ubiquitin specific peptidase 5 (isopeptidase T) isoform 1 , ubiquitin specific peptidase 5 (isopeptidase T) isoform 2 , ubiquitin specific protease 5 , ubiquitin specific peptidase 5 , deubiquitinating enzyme 5 , isopeptidase T , ubiquitin isopeptidase T , ubiquitin specific protease 5 (isopeptidase T) , ubiquitin thioesterase 5 , ubiquitin thiolesterase 5 , ubiquitin-specific protease-5 (ubiquitin isopeptidase T) , ubiquitin-specific-processing protease 5 , ubiquitin carboxy terminal hydrolase T

GENE ID SPECIES
505280 Bos taurus
3259330 Cryptococcus neoformans var. neoformans JEC21
3410770 Entamoeba histolytica HM-1:IMSS
6009870 Coprinopsis cinerea okayama7130
9228979 Arthroderma otae CBS 113480
10185831 Cryptococcus gattii WM276
3790547 Plasmodium yoelii yoelii 17XNL
100347902 Oryctolagus cuniculus
8078 Homo sapiens
22225 Mus musculus
486718 Canis lupus familiaris
297593 Rattus norvegicus
Selected quality suppliers for anti-USP5 (USP5) Antibodies
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