Ubiquitin Specific Peptidase 6 (USP6) ELISA Kits

Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Additionally we are shipping USP6 Antibodies (63) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human USP6 USP6 9098 P35125
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More ELISA Kits for USP6 Interaction Partners

Human Ubiquitin Specific Peptidase 6 (USP6) interaction partners

  1. our studies highlight Jak1 (show JAK1 ELISA Kits) as the first identified substrate for USP6, and they offer a mechanistic rationale for the clinical investigation of Jak (show JAK3 ELISA Kits) and STAT3 (show STAT3 ELISA Kits) inhibitors as therapeutics for the treatment of bone and soft tissue tumors along with other neoplasms driven by USP6 overexpression

  2. Molecular analyses revealed the presence and amplification of the novel PPPR6-USP6 gene fusion, which resulted in USP6 mRNA transcriptional upregulation. These findings further support the oncogenic role of the USP6 protease in mesenchymal neoplasia and expand the biologic potential of Nodular fasciitis

  3. It was shown that TRE17 activates the classical NF-kappa B (show NFKB1 ELISA Kits) pathway through an atypical mechanism that does not involve IkappaB degradation. Optimal activation of NF-kappa B (show NFKB1 ELISA Kits) by TRE17 required both catalytic subunits of IkappaB kinase (show CHUK ELISA Kits).

  4. USP6 fluorescence in-situ hybridization is a useful ancillary test in cases where nodular fasciitis is a potential diagnostic consideration.

  5. the deubiquitylase ubiquitin-specific protease 6 (USP6) as a potent activator of Wnt (show WNT2 ELISA Kits) signaling. USP6 enhances Wnt (show WNT2 ELISA Kits) signaling by deubiquitylating Fzds, thereby increasing their cell-surface abundance.

  6. TRE17/USP6 regulates ubiquitylation and trafficking of cargo proteins that enter cells by clathrin-independent endocytosis

  7. 8 of the 9 giant cell reparative granulomas from hands and feet showed rearrangements of the USP6 gene compared with none of 8 gnathic lesions

  8. we discuss the clinicopathologic features, molecular pathology, and pathogenesis of ABC (show ABCB6 ELISA Kits) and nodular fasciitis in relation to USP6

  9. identification of a USP6 gene rearrangement is helpful in making a diagnosis of nodular fasciitis.

  10. manipulating USP6 expression levels alters the ability of cells to migrate and to divide. Cell proliferation and progression through cytokinesis depend on USP6 expression

USP6 Antigen Profile

Antigen Summary

Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6- dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Gene names and symbols associated with USP6

  • ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (CNG04540) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (ANI_1_2152104) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (AOR_1_208094) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (MCYG_00569) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (CC1G_15273) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (MGYG_01395) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (CGB_G0160W) antibody
  • ubiquitin carboxyl-terminal hydrolase 6 (LOC100282385) antibody
  • HRP1 antibody
  • Tre-2 antibody
  • TRE2 antibody
  • TRE17 antibody
  • USP6-short antibody

Protein level used designations for USP6

TBC1D3 and USP32 fusion , deubiquitinating enzyme 6 , hyperpolymorphic gene 1 , proto-oncogene TRE-2 , tre-2 oncogene , ubiquitin carboxyl-terminal hydrolase 6 , ubiquitin specific peptidase 6- , ubiquitin specific protease 6 (Tre-2 oncogene) , ubiquitin thioesterase 6 , ubiquitin thiolesterase 6 , ubiquitin-specific protease USP6 , ubiquitin-specific-processing protease 6

GENE ID SPECIES
9098 Homo sapiens
3258713 Cryptococcus neoformans var. neoformans JEC21
4986188 Aspergillus niger CBS 513.88
5996141 Aspergillus oryzae RIB40
9225689 Arthroderma otae CBS 113480
9380325 Coprinopsis cinerea okayama7130
10032643 Arthroderma gypseum CBS 118893
10190832 Cryptococcus gattii WM276
100282385 Zea mays
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