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anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) Antibodies

Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Additionally we are shipping USP7 Proteins (8) and USP7 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP7 252870 Q6A4J8
USP7 7874 Q93009
USP7 360471 Q4VSI4
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Top anti-USP7 Antibodies at antibodies-online.com

Showing 10 out of 150 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB USP7 Antibody (Center) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the USP7 antibody detected the USP7 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using HAUSP mouse mAb against MCF-7 (1) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-USP7 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: A549 cell lysate WB Suggested Anti-USP7  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: A549 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB USP7 Antibody (Center)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the USP7 antibody detected the USP7 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-USP7 Pab (ABIN388889) is used in Western blot to detect USP7 in T-47D cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details

USP7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-USP7 Antibodies

  1. Cow (Bovine) Polyclonal USP7 Primary Antibody for EIA, WB - ABIN401255 : Sheng, Saridakis, Sarkari, Duan, Wu, Arrowsmith, Frappier: Molecular recognition of p53 and MDM2 by USP7/HAUSP. in Nature structural & molecular biology 2006 (PubMed)
    Show all 5 references for ABIN401255

  2. Human Polyclonal USP7 Primary Antibody for EIA, WB - ABIN955493 : Sarkari, La Delfa, Arrowsmith, Frappier, Sheng, Saridakis: Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7. in Journal of molecular biology 2010 (PubMed)
    Show all 5 references for ABIN955493

  3. Human Polyclonal USP7 Primary Antibody for EIA, IHC (p) - ABIN357533 : Puente, Sánchez, Overall, López-Otín: Human and mouse proteases: a comparative genomic approach. in Nature reviews. Genetics 2003 (PubMed)
    Show all 5 references for ABIN357533

  4. Human Monoclonal USP7 Primary Antibody for EIA, WB - ABIN1109455 : Becker, Marchenko, Maurice, Moll: Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma. in Cell death and differentiation 2007 (PubMed)
    Show all 3 references for ABIN1109455

  5. Human Monoclonal USP7 Primary Antibody for ELISA, WB - ABIN969186 : Daubeuf, Singh, Tan, Liu, Federoff, Bowers, Tolba: HSV ICP0 recruits USP7 to modulate TLR-mediated innate response. in Blood 2009 (PubMed)
    Show all 3 references for ABIN969186

More Antibodies against USP7 Interaction Partners

Fruit Fly (Drosophila melanogaster) Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) interaction partners

  1. reveal a conserved mechanism by which Ci/Gli (show GLI1 Antibodies) is stabilized by a deubiquitination enzyme and identify Usp7/HUASP as a critical regulator of Hh signaling and potential therapeutic target for Hh-related cancers

  2. Genetic and gene expression analyses suggested that GMPS (show GMPS Antibodies)/USP7 acts as a transcriptional corepressor

  3. GMP synthetase (show GMPS Antibodies) stimulates histone H2B deubiquitylation by the epigenetic silencer USP7

Mouse (Murine) Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) interaction partners

  1. demonstrate that genotoxic stress stimulates Cry1 (show CRY1 Antibodies) phosphorylation and its deubiquitination by Herpes virus associated ubiquitin-specific protease (Hausp, a.k.a Usp7), stabilizing Cry1 (show CRY1 Antibodies) and shifting circadian clock time

  2. Our results demonstrate that the SCML2 (show SCML2 Antibodies)/USP7 complex constitutes a novel molecular pathway in modulating the epigenetic state of sex chromosomes during male meiosis

  3. USP7-mediated mono-deubiquitination of FoxO1 (show FOXO1 Antibodies) results in suppression of FoxO1 (show FOXO1 Antibodies) transcriptional activity through decreased FoxO1 (show FOXO1 Antibodies) occupancy on the promoters of gluconeogenic genes.

  4. Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60 (show KAT5 Antibodies).

  5. The ubiquitination-deubiquitination cascade mediated by the TRIM27 (show RFP Antibodies)-USP7 complex plays an important role in TNF-alpha (show TNF Antibodies)-induced apoptosis.

  6. the stability and activity of PPARgamma2 (show PPARG Antibodies) are modulated by the deubiquitinating activity of HAUSP, which may be a target for the development of anti-diabetic drugs.

  7. data reveal a molecular mechanism in which rapid temporal control of Foxp3 (show FOXP3 Antibodies) expression in Treg cells can be regulated by USP7, thereby modulating Treg cell numbers and function

  8. These results indicate that HAUSP-mediated p53 (show TP53 Antibodies) regulation is crucial for brain development, and also suggest that both the p53 (show TP53 Antibodies)-dependent and the p53 (show TP53 Antibodies)-independent functions of HAUSP contribute to the neonatal lethality of hausp-mutant mice.

  9. HAUSP knockout mice embryos showed p53 (show TP53 Antibodies) activation, but no increase in apoptosis.

  10. USP7 (HAUSP) is proteolytically processed upon dexamethasone-, gamma-irradiation-, and antigen-induced cell death. Such processing of HAUSP does not occur in caspase 3 (show CASP3 Antibodies)-/- thymocytes.

Human Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) interaction partners

  1. USP7 suppresses H2O2-induced mutagenesis involving cell-cycle-independent processes such as DNA repair.

  2. This study identified USP7 as a replisome-enriched SUMO deubiquitinase that is essential for DNA replication.

  3. We now report the identification of a novel molecular function of STIP (show ELP2 Antibodies) that links USP7 to the p53 (show TP53 Antibodies)-Mdm2 (show MDM2 Antibodies) pathway

  4. USP7 interacts with vIRF1 in U2OS cells.

  5. HAUSP-nucleolin (show NCL Antibodies) interaction is regulated by p53 (show TP53 Antibodies)-Mdm2 (show MDM2 Antibodies) complex in response to DNA damage.

  6. USP7-mediated de-ubiquitylation protects Rad18 (show RAD18 Antibodies) from proteasomal degradation and is necessary for the integrity of the specialized translesion synthesis pathway

  7. USP7 allosterically regulates the conformational states of UHRF1 (show UHRF1 Antibodies) and affects chromatin association of UHRF1 (show UHRF1 Antibodies).

  8. Taken together, our results reveal that oxidative and ER stress, rather than the Mdm2 (show MDM2 Antibodies)-p53 (show TP53 Antibodies) axis, mainly contributes to USP7 inhibitor-mediated apoptosis in cancer cells.

  9. Data suggest that ubiquitin thioesterase 7 (HAUSP) may act as an oncogenic protein that can modulate c-MYC (show MYC Antibodies) protein expression via transformation-transcription domain-associated protein (TRRAP (show TRRAP Antibodies)).

  10. These studies reveal that USP7-mediated stabilization of DNMT1 (show DNMT1 Antibodies) is regulated by acetylation and provide a structural basis for the design of inhibitors.

USP7 Antigen Profile

Protein Summary

Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6 (By similarity).

Gene names and symbols associated with USP7

  • ubiquitin-specific protease 7 (Usp7) antibody
  • ubiquitin specific peptidase 7 (herpes virus-associated) (usp7) antibody
  • ubiquitin specific peptidase 7 (herpes virus-associated) (USP7) antibody
  • ubiquitin specific peptidase 7 (Usp7) antibody
  • ubiquitin specific peptidase 7 (herpes virus-associated) (Usp7) antibody
  • 2210010O09Rik antibody
  • AA409944 antibody
  • AA617399 antibody
  • AU019296 antibody
  • AW548146 antibody
  • C80752 antibody
  • CG1490 antibody
  • Dmel\\CG1490 antibody
  • HAUSP antibody
  • TEF1 antibody
  • UBP antibody
  • USP7 antibody

Protein level used designations for USP7

CG1490-PB , Usp7-PB , ubiquitin specific peptidase 7 (herpes virus-associated) , ubiquitin carboxyl-terminal hydrolase 7-like , deubiquitinating enzyme 7 , herpesvirus-associated ubiquitin-specific protease , mHAUSP , ubiquitin carboxyl-terminal hydrolase 7 , ubiquitin specific protease 7 , ubiquitin thioesterase 7 , ubiquitin thiolesterase 7 , ubiquitin-specific-processing protease 7 , Herpes virus-associated ubiquitin-specific protease , ubiquitin specific protease 7 (herpes virus-associated) , herpes-virus-associated ubiquitin-specific protease , rHAUSP , ubiquitin-specific peptidase 7

GENE ID SPECIES
32169 Drosophila melanogaster
100201254 Hydra magnipapillata
100468835 Ailuropoda melanoleuca
252870 Mus musculus
7874 Homo sapiens
360471 Rattus norvegicus
395126 Gallus gallus
479854 Canis lupus familiaris
100190899 Sus scrofa
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