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Ubiquitin-Conjugating Enzyme E2D 1 Proteins (UBE2D1)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2D 1 Antibodies (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBE2D1 7321 P51668
Mouse UBE2D1 UBE2D1 216080 P61080
UBE2D1 361831 D3ZDK2
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Top Ubiquitin-Conjugating Enzyme E2D 1 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$173.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 2 to 3 Days
$393.75
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 10 to 12 Days
$237.60
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UBE2D1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Top referenced Ubiquitin-Conjugating Enzyme E2D 1 Proteins

  1. Human UBE2D1 Protein expressed in Escherichia coli (E. coli) - ABIN667460 : Pabarcus, Hoe, Sadeghi, Patterson, Wiertz, Correia: CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases. in Archives of biochemistry and biophysics 2009 (PubMed)
    Show all 2 references for ABIN667460

  2. Human UBE2D1 Protein expressed in Escherichia coli (E. coli) - ABIN2004281 : Grou, Carvalho, Pinto, Wiese, Piechura, Meyer, Warscheid, Sá-Miranda, Azevedo: Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor. in The Journal of biological chemistry 2008 (PubMed)

More Proteins for Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) interaction partners

  1. Data show that ubiquitin E2 enzymes UBE2D1/2/3 and E3 ligase RNF138 (show RNF138 Proteins) accumulate at DNA-damage sites and act at early resection stages by promoting CtIP (show RBBP8 Proteins) protein ubiquitylation and accrual.

  2. The Asp17 mutation in MDM2 stimulated its discharge of the UBCH5a-ubiquitin thioester adduct.

  3. The SMURF2:UBCH5 complex is critical in maintaining KRAS protein stability.

  4. Biochemical characterization of recombinant UBTD1 and UBE2D demonstrated that the two proteins form a stable, stoichiometric complex that can be purified to near homogeneity.

  5. crystal structure of the dimeric RING domain of rat RNF4 in complex with E2 (UbcH5A) linked by an isopeptide bond to ubiquitin

  6. These data demonstrate that the ability of ICP0 to interact with cellular E2 ubiquitin-conjugating enzyme UBE2D1 is fundamentally important for its biological functions during HSV-1 infection.

  7. identify the IDOL (show MYLIP Proteins)-UBE2D complex as an important determinant of LDLR (show LDLR Proteins) activity, and provide insight into molecular mechanisms underlying the regulation of cholesterol uptake

  8. This structure reveals an interaction between the ubiquitin surface flanking K11 and residues adjacent to the E2 catalytic cysteine and suggests a possible role for this surface in formation of K11 linkages.

  9. The authors demonstrate that c-IAP1 (show BIRC2 Proteins) and UbcH5 family promote K11-linked polyubiquitination of receptor-interacting protein 1 (RIP1 (show RIPK1 Proteins)) in vitro and in vivo.

  10. Whereas UbcH5(A, B and C) is highly efficient in converting IkBa into monoubiquitinated forms, Cdc34 drives ubiquitin (Ub)-Ub conjugation

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) interaction partners

  1. Its gene expression is inhibited through p53 (show TP53 Proteins) dependent apoptosis, which is induced by cadmium exposure.(review)

  2. significantly elevated levels of SFT/UbcH5A mRNA in the neonatal mouse and its localization to choroid plexus suggest that this factor may contribute to the rapid rate of brain iron uptake that occurs in the early postnatal period

Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) Protein Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with UBE2D1

  • ubiquitin-conjugating enzyme E2D 1 (UBE2D1)
  • ubiquitin-conjugating enzyme E2D 1 (ube2d1)
  • ubiquitin-conjugating enzyme E2D 1 (LOC100341090)
  • ubiquitin-conjugating enzyme E2D 1 (LOC100355225)
  • ubiquitin-conjugating enzyme E2D 1 (Ube2d1)
  • ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) (UBE2D1)
  • ubiquitin-conjugating enzyme E2D 1b (ube2d1b)
  • E2(17)KB1 protein
  • SFT protein
  • UBC4/5 protein
  • UBCH5 protein
  • UBCH5A protein
  • ube2d1 protein
  • wu:fc16h06 protein
  • zgc:73096 protein

Protein level used designations for UBE2D1

ubiquitin-conjugating enzyme E2 D1 , ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) , ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog) , ubiquitin-conjugating enzyme E2D 1 , UBC4/5 homolog , stimulator of Fe transport , ubiquitin carrier protein D1 , ubiquitin-conjugating enzyme E2(17)KB 1 , ubiquitin-conjugating enzyme E2-17 kDa 1 , ubiquitin-protein ligase D1 , E2(17)KB 1 , ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog

GENE ID SPECIES
701491 Macaca mulatta
745141 Pan troglodytes
780353 Xenopus (Silurana) tropicalis
100341090 Oryctolagus cuniculus
100355225 Oryctolagus cuniculus
495381 Xenopus laevis
7321 Homo sapiens
608578 Canis lupus familiaris
535287 Bos taurus
216080 Mus musculus
361831 Rattus norvegicus
423641 Gallus gallus
324015 Danio rerio
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