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Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) ELISA Kits

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2D 2 Antibodies (82) and Ubiquitin-Conjugating Enzyme E2D 2 Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human UBE2D2 UBE2D2 7322 P62837
Anti-Rat UBE2D2 UBE2D2 641452 P62839
Anti-Mouse UBE2D2 UBE2D2 56550 P62838
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More ELISA Kits for Ubiquitin-Conjugating Enzyme E2D 2 Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

  1. mutations having marked effects on function only minimally affect the intermolecular interactions between the AO7 (show RNF25 ELISA Kits) RING and UbcH5B, establishing a high degree of complexity in activation through the RING-E2 interface.

  2. Data show that ubiquitin E2 enzymes UBE2D1 (show UBE2D1 ELISA Kits)/2/3 and E3 ligase RNF138 (show RNF138 ELISA Kits) accumulate at DNA-damage sites and act at early resection stages by promoting CtIP (show RBBP8 ELISA Kits) protein ubiquitylation and accrual.

  3. together with UBE2L3 (show UBE2L3 ELISA Kits) and UBE2N (show UBE2N ELISA Kits), synergistically contribute to Parkin (show PARK2 ELISA Kits)-mediated mitophagy

  4. Presented is the structure of the human dimeric RING domain from BIRC7 (show BIRC7 ELISA Kits) in complex with the E2 UbcH5B covalently linked to Ub.

  5. Whereas UbcH5(A, B and C) is highly efficient in converting IkBa into monoubiquitinated forms, Cdc34 drives ubiquitin (Ub)-Ub conjugation

  6. determined the 2.2 A crystal structure of an intermediate of UbcH5b approximately ubiquitin (Ub) conjugate, which is assembled into an infinite spiral through the backside interaction.

  7. role of WW3 and WW4 domains of Nedd4-2 in dopamine transporter ubiquitination was demonstrated; siRNA analysis demonstrated that this polyubiquitination is mediated by Nedd4-2 cooperation with UBE2D and UBE2L3 E2 ubiquitin-conjugating enzymes

  8. Results describe the crystal structure of a complex between the HECT domain of NEDD4L and the E2 UbcH5B bearing a covalently linked Ub at its active site (UbcH5B approximately Ub).

  9. Data show that binding of the CNOT4 (show CNOT4 ELISA Kits) RING finger (show PCGF1 ELISA Kits) to the ubiquitin-conjugating enzyme (E2 (show UBE2D4 ELISA Kits)) UbcH5B is highly selective.

  10. UbcH5B/C are E2s for Mdm2 (show MDM2 ELISA Kits), which contribute to the maintenance of low levels of p53 (show TP53 ELISA Kits) and Mdm2 (show MDM2 ELISA Kits) in unstressed cells; inhibition of p53 (show TP53 ELISA Kits) ubiquitination and degradation by targeting UbcH5B/C is not sufficient to up-regulate p53 (show TP53 ELISA Kits) transcriptional activity.

Pig (Porcine) Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Antigen Profile

Antigen Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Gene names and symbols associated with UBE2D2

  • ubiquitin-conjugating enzyme E2D 2 (ube2d2) antibody
  • zgc:77149 (zgc:77149) antibody
  • ubiquitin-conjugating enzyme E2D 2 (UBE2D2) antibody
  • ubiquitin-conjugating enzyme E2D 2 (Ube2d2) antibody
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2l) antibody
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2) antibody
  • ubiquitin-conjugating enzyme E2D 2A (Ube2d2a) antibody
  • ubiquitin-conjugating enzyme E2D 3 (ube2d3) antibody
  • 1500034D03Rik antibody
  • E2(17)KB2 antibody
  • E217kB antibody
  • PUBC1 antibody
  • Ubc2e antibody
  • ubc4 antibody
  • UBC4/5 antibody
  • UBCH5B antibody
  • Ube2d2 antibody
  • ube2d3.1 antibody
  • wu:fj13d01 antibody
  • xubc4 antibody
  • zgc:55886 antibody
  • zgc:73200 antibody

Protein level used designations for UBE2D2

ubiquitin-conjugating enzyme E2D 2 , ubiquitin-conjugating enzyme E2 D2 , p53-regulated ubiquitin-conjugating enzyme 1 , ubiquitin carrier protein D2 , ubiquitin-conjugating enzyme E2-17 kDa 2 , ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5) , ubiquitin-protein ligase D2 , E2(17)KB 2 , ubc2e ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme E2(17)KB 2 , ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) , UB2D2 , ubiquitin-conjugating enzyme E2 D3 , ubiquitin conjugating enzyme 2e , ubiquitin carrier protein 4 , ubiquitin conjugating enzyme E2 , ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog)

GENE ID SPECIES
100194508 Salmo salar
393934 Danio rerio
7322 Homo sapiens
641452 Rattus norvegicus
416137 Gallus gallus
612742 Canis lupus familiaris
780418 Sus scrofa
541003 Bos taurus
335444 Danio rerio
446340 Xenopus laevis
56550 Mus musculus
403384 Xenopus laevis
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