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Ubiquitin-Conjugating Enzyme E2D 2 Proteins (UBE2D2)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2D 2 Antibodies (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBE2D2 7322 P62837
Rat UBE2D2 UBE2D2 641452 P62839
Mouse UBE2D2 UBE2D2 56550 P62838
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Top Ubiquitin-Conjugating Enzyme E2D 2 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag   3 nM Log in to see 2 to 3 Days
$330.75
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 2 to 3 Days
$393.75
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,321.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Escherichia coli (E. coli) Xenopus laevis His tag   50 μg Log in to see 10 to 12 Days
$237.60
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 1 to 2 Days
$443.33
Details

UBE2D2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

Top referenced Ubiquitin-Conjugating Enzyme E2D 2 Proteins

  1. Human UBE2D2 Protein expressed in Escherichia coli (E. coli) - ABIN667507 : Ciechanover, Schwartz: The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994 (PubMed)
    Show all 2 references for ABIN667507

More Proteins for Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

  1. mutations having marked effects on function only minimally affect the intermolecular interactions between the AO7 (show RNF25 Proteins) RING and UbcH5B, establishing a high degree of complexity in activation through the RING-E2 interface.

  2. Data show that ubiquitin E2 enzymes UBE2D1 (show UBE2D1 Proteins)/2/3 and E3 ligase RNF138 (show RNF138 Proteins) accumulate at DNA-damage sites and act at early resection stages by promoting CtIP (show RBBP8 Proteins) protein ubiquitylation and accrual.

  3. together with UBE2L3 (show UBE2L3 Proteins) and UBE2N (show UBE2N Proteins), synergistically contribute to Parkin (show PARK2 Proteins)-mediated mitophagy

  4. Presented is the structure of the human dimeric RING domain from BIRC7 (show BIRC7 Proteins) in complex with the E2 UbcH5B covalently linked to Ub.

  5. Whereas UbcH5(A, B and C) is highly efficient in converting IkBa into monoubiquitinated forms, Cdc34 drives ubiquitin (Ub)-Ub conjugation

  6. determined the 2.2 A crystal structure of an intermediate of UbcH5b approximately ubiquitin (Ub) conjugate, which is assembled into an infinite spiral through the backside interaction.

  7. role of WW3 and WW4 domains of Nedd4-2 in dopamine transporter ubiquitination was demonstrated; siRNA analysis demonstrated that this polyubiquitination is mediated by Nedd4-2 cooperation with UBE2D and UBE2L3 E2 ubiquitin-conjugating enzymes

  8. Results describe the crystal structure of a complex between the HECT domain of NEDD4L (show NEDD4L Proteins) and the E2 UbcH5B bearing a covalently linked Ub at its active site (UbcH5B approximately Ub).

  9. Data show that binding of the CNOT4 (show CNOT4 Proteins) RING finger (show PCGF1 Proteins) to the ubiquitin-conjugating enzyme (E2 (show UBE2D4 Proteins)) UbcH5B is highly selective.

  10. UbcH5B/C are E2s for Mdm2 (show MDM2 Proteins), which contribute to the maintenance of low levels of p53 (show TP53 Proteins) and Mdm2 (show MDM2 Proteins) in unstressed cells; inhibition of p53 (show TP53 Proteins) ubiquitination and degradation by targeting UbcH5B/C is not sufficient to up-regulate p53 (show TP53 Proteins) transcriptional activity.

Pig (Porcine) Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Protein Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Gene names and symbols associated with UBE2D2

  • ubiquitin-conjugating enzyme E2D 2 (ube2d2)
  • zgc:77149 (zgc:77149)
  • ubiquitin-conjugating enzyme E2D 2 (UBE2D2)
  • ubiquitin-conjugating enzyme E2D 2 (Ube2d2)
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2l)
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2)
  • ubiquitin-conjugating enzyme E2D 2A (Ube2d2a)
  • ubiquitin-conjugating enzyme E2D 3 (ube2d3)
  • 1500034D03Rik protein
  • E2(17)KB2 protein
  • E217kB protein
  • PUBC1 protein
  • Ubc2e protein
  • ubc4 protein
  • UBC4/5 protein
  • UBCH5B protein
  • Ube2d2 protein
  • ube2d3.1 protein
  • wu:fj13d01 protein
  • xubc4 protein
  • zgc:55886 protein
  • zgc:73200 protein

Protein level used designations for UBE2D2

ubiquitin-conjugating enzyme E2D 2 , ubiquitin-conjugating enzyme E2 D2 , p53-regulated ubiquitin-conjugating enzyme 1 , ubiquitin carrier protein D2 , ubiquitin-conjugating enzyme E2-17 kDa 2 , ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5) , ubiquitin-protein ligase D2 , E2(17)KB 2 , ubc2e ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme E2(17)KB 2 , ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) , UB2D2 , ubiquitin-conjugating enzyme E2 D3 , ubiquitin conjugating enzyme 2e , ubiquitin carrier protein 4 , ubiquitin conjugating enzyme E2 , ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog)

GENE ID SPECIES
100194508 Salmo salar
393934 Danio rerio
7322 Homo sapiens
641452 Rattus norvegicus
416137 Gallus gallus
612742 Canis lupus familiaris
780418 Sus scrofa
541003 Bos taurus
335444 Danio rerio
446340 Xenopus laevis
56550 Mus musculus
403384 Xenopus laevis
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