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Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Additionally we are shipping UBE2Q2 Antibodies (49) and UBE2Q2 Proteins (9) and many more products for this protein.
The newly characterized human gene, UBE2Q2, may have implications for the pathogenesis of acute lymphoblastic leukemia.
In the 21 breast cancer cases investigated, a high increase in UBE2Q2 expression was found in 8 breast cancers (38.1%), a moderately increased UBE2Q2 expression was observed in 7 cases (33.3%), and no sig (show PICALM ELISA Kits). changes were detected in 6 cases (28.6%).
Found high expression levels of UBE2Q2 in human head and neck carcinoma cell lines and cancer tissues; found the level of UBE2Q2 is decreased in cell lines and cancer tissues that have resistance to CDDP or docetaxel.
Inhibition of the UBE2Q2 protein causes cells to undergo a prolonged prophase arrest suggesting that UBE2Q2 normally functions to antagonize an early mitotic checkpoint (show BUB3 ELISA Kits).
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination (By similarity).
ubiquitin-conjugating enzyme E2Q 2
, ubiquitin-conjugating enzyme E2 Q2
, ubiquitin carrier protein Q2
, ubiquitin-protein ligase Q2
, ubiquitin-conjugating enzyme E2Q (putative) 2
, ubiquitin-conjugating enzyme UBCi