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Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2R 2 Antibodies (64) and Ubiquitin-Conjugating Enzyme E2R 2 Proteins (10) and many more products for this protein.
Study shows that Ube2R1 (show CDC34 ELISA Kits)/2 forms a salt bridge interaction between a conserved Asp (show ASIP ELISA Kits) residue on Ube2R1 (show CDC34 ELISA Kits)/2 and acceptor ubiquitin residue Arg 54 and that perturbation of this interaction leads to the severe loss of UbeR2 activity. Results also provide new insight into how the Ube2R1 (show CDC34 ELISA Kits)/2 acidic loop may participate in catalysis.
Protein kinase CK2 (show CSNK2A1 ELISA Kits) dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TRCp (show BTRC ELISA Kits) and enhances beta-catenin (show CTNNB1 ELISA Kits) degradation [UBC3B]
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
ubiquitin carrier protein R2
, ubiquitin-conjugating enzyme E2 R2
, ubiquitin-conjugating enzyme E2-CDC34B
, ubiquitin-conjugating enzyme UBC3B
, ubiquitin-protein ligase R2
, ubiquitin-conjugating enzyme E2R 2
, ubiquitin coniugating enzyme 3b
, Ubiquitin-conjugating enzyme E2 R2
, ubiquitin-conjugating enzyme E2-32k
, uncharacterized protein LOC689226