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Ubiquitin-Fold Modifier 1 Proteins (UFM1)

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1\; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M\; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Dec 2008].. Additionally we are shipping UFM1 Antibodies (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UFM1 51569 P61960
Mouse UFM1 UFM1 67890 P61961
UFM1 365797 Q5BJP3
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Top UFM1 Proteins at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,123.00
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,123.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,123.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,123.00
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,123.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,123.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,123.00
Details

UFM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, , ,
Rat (Rattus)

Top referenced UFM1 Proteins

  1. Human UFM1 Protein expressed in Escherichia coli (E. coli) - ABIN667370 : Sasakawa, Sakata, Yamaguchi, Komatsu, Tatsumi, Kominami, Tanaka, Kato: Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1. in Biochemical and biophysical research communications 2006 (PubMed)
    Show all 2 references for ABIN667370

More Proteins for Ubiquitin-Fold Modifier 1 (UFM1) Interaction Partners

Human Ubiquitin-Fold Modifier 1 (UFM1) interaction partners

  1. results of an in vitro truncation assay suggest that Uba5 (show UBA5 Proteins) residues 57-363 comprise the minimal fragment required for the high-efficiency activation of Ufm1

  2. ASC1 (show RPL3 Proteins) is a target for ufmylation and that UFBP1 is an essential component for ASC1 (show RPL3 Proteins) ufmylation.

  3. binding of ATP to Uba5 (show UBA5 Proteins) approximately Ufm1 thioester was required for efficient transfer of Ufm1 from Uba5 (show UBA5 Proteins) to Ufc1 (show UFC1 Proteins) via transthiolation.

  4. Thus, UfSP2 proteins have protease- and Ufm1-independent functions in GPCR biogenesis.

  5. transcription downregulation of the Ufm1 and FAT10 (show UBD Proteins) conjugation system in liver Mallory-Denk bodies formation

  6. NCAM140 interacts with ufc1 (show UFC1 Proteins) and its trafficking and endocytosis is upregulated in the presense of Ufm1.

  7. the Ufm1 system plays a critical role in vesicle trafficking, and its inhibition may lead to protein overload in the ER and UPR activation.

  8. A novel type of E3 ligase for the Ufm1 conjugation system.

  9. The solution structure and dynamics of human Ufm1 (hsUfm1) by nuclear magnetic resonance spectroscopy was analysed.

Mouse (Murine) Ubiquitin-Fold Modifier 1 (UFM1) interaction partners

  1. High UFM1 expression is associated with Atherosclerosis.

  2. transcription downregulation of the Ufm1 and FAT10 (show UBD Proteins) conjugation system in liver Mallory-Denk bodies formation

  3. These data suggest that UFM1-UFBP1 participate in preventing ER stress-induced apoptosis in protein secretory cells.

  4. A novel type of E3 ligase for the Ufm1 conjugation system.

  5. A novel ubiquitin fold modifier (Ufm1) not been previously associated with ER stress and not found to be induced under any condition was found to be upregulated in the hearts of MCP (show CR1L Proteins) mice (transgenic mice that express MCP-1 (show CPT1B Proteins) specifically in the heart).

  6. loop between beta3 and alpha2 in addition to the C-terminal region of Ufm1 plays a role in binding to UfSP1

UFM1 Protein Profile

Protein Summary

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1\; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M\; MIM 603173) (Komatsu et al., 2004

Gene names and symbols associated with UFM1

  • ubiquitin-fold modifier 1 (UFM1)
  • ubiquitin-fold modifier 1 (ufm1)
  • ubiquitin-fold modifier 1 (AT1G77710)
  • ubiquitin-fold modifier 1 (Ufm1)
  • ubiquitin-fold modifier 1 (PR46a)
  • 1810045K17Rik protein
  • AI132708 protein
  • AI463323 protein
  • bA131P10.1 protein
  • BM-002 protein
  • C13orf20 protein
  • ENSMUSG00000074598 protein
  • Gm10726 protein
  • RGD1304890 protein
  • T32E8.4 protein
  • T32E8_4 protein
  • ubfm1 protein
  • wu:fa10f05 protein
  • wu:fb72g01 protein
  • zgc:55335 protein

Protein level used designations for UFM1

ubiquitin-fold modifier 1

GENE ID SPECIES
452546 Pan troglodytes
477297 Canis lupus familiaris
549742 Xenopus (Silurana) tropicalis
695866 Macaca mulatta
844107 Arabidopsis thaliana
100528343 Ictalurus punctatus
51569 Homo sapiens
67890 Mus musculus
365797 Rattus norvegicus
530547 Bos taurus
418894 Gallus gallus
100286585 Salmo salar
100172209 Pongo abelii
495839 Xenopus laevis
322756 Danio rerio
5722153 Chlamydomonas reinhardtii
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