You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) Antibodies

The protein encoded by UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. Additionally we are shipping UBA1 Proteins (11) and UBA1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBA1 7317 P22314
UBA1 22201 Q02053
UBA1 314432 Q5U300
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-UBA1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UBA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB UBA1 Antibody (N-term) (ABIN658476) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the UBA1 antibody detected the UBA1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated EIA, IHC (p), WB 0.5 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of UBA1 expression in rat liver extract (lane 1), mouse liver extract (lane 2), mouse testis extract (lane 3) and HELA whole cell lysates (lane 4). UBA1 at 117KD was detected using rabbit anti- UBA1 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Affinity Purified anti-Ubiquitin Activating Enzyme antibody was used at a 10 µg/ml to detect UBE1 in a variety of tissues including adrenal, breast, colon (epithelium), kidney, liver, lung (respiratory epithelium), ovary (oocyte and endothelium), pancreas (islet and exocrine), placenta, prostate (epithelium), skin (epithelium), spleen (lymphocytes), stomach (chief), testis, thymus, tonsil, and uterus (glandular, stroma). In many cells a punctate nuclear staining was observed. Other cells showed both cytoplasmic and nuclear staining. This image shows UBE1 staining of human lung tissue. Tissue was formalin-fixed and paraffin embedded. Personal Communi-cation, Tina Roush, LifeSpanBiosciences, Seattle, WA. Immunohistochemistry. antibodies-online's Affinity Purified anti-Ubiquitin Activating Enzyme antibody was used at a 10 ug/ml to detect UBE1 in a variety of tissues including adrenal, breast, colon (epithelium), kidney, liver, lung (respiratory epithelium), ovary (oocyte and endothelium), pancreas (islet and exocrine), placenta, prostate (epithelium), skin (epithelium), spleen (lymphocytes), stomach (chief), testis, thymus, tonsil, and uterus (glandular, stroma). In many cells a punctate nuclear staining was observed. Other cells showed both cytoplasmic and nuclear staining. This image shows UBE1 staining of human lung tissue. Tissue was formalinfixed and paraffin embedded. Personal Communi-cation, Tina Roush, LifeSpanBiosciences, Seattle, WA. 500 μg Log in to see 2 to 3 Days
$369.00
Details
Human Rabbit Un-conjugated WB UBA1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

UBA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
,
,
, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-UBA1 Antibodies

  1. Dog (Canine) Polyclonal UBA1 Primary Antibody for EIA, IHC (p) - ABIN401028 : Saito, Doi, Yamagishi, Ishihara, Hatayama: Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems. in Biochemical and biophysical research communications 2004 (PubMed)
    Show all 6 references for ABIN401028

  2. Human Polyclonal UBA1 Primary Antibody for EIA, IHC (p) - ABIN357486 : Ayusawa, Kaneda, Itoh, Yasuda, Murakami, Sugasawa, Hanaoka, Seno: Complementation by a cloned human ubiquitin-activating enzyme E1 of the S-phase-arrested mouse FM3A cell mutant with thermolabile E1. in Cell structure and function 1992 (PubMed)
    Show all 5 references for ABIN357486

  3. Human Polyclonal UBA1 Primary Antibody for IHC (p), WB - ABIN658476 : Carbia-Nagashima, Gerez, Perez-Castro, Paez-Pereda, Silberstein, Stalla, Holsboer, Arzt: RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. in Cell 2007 (PubMed)
    Show all 2 references for ABIN658476

  4. Cow (Bovine) Polyclonal UBA1 Primary Antibody for WB - ABIN2774233 : Ramser, Ahearn, Lenski, Yariz, Hellebrand, von Rhein, Clark, Schmutzler, Lichtner, Hoffman, Meindl, Baumbach-Reardon: Rare missense and synonymous variants in UBE1 are associated with X-linked infantile spinal muscular atrophy. in American journal of human genetics 2008 (PubMed)
    Show all 2 references for ABIN2774233

More Antibodies against UBA1 Interaction Partners

Human Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) interaction partners

  1. recent findings put UBA1 at the center of cellular homeostasis and neurodegeneration [review]

  2. A ubiquitin shuttle DC-UbP reconciles protein ubiquitination and deubiquitination via linking UbE1 and USP5 (show USP5 Antibodies) enzymes.

  3. Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 (show UBD Antibodies) targets it for proteasomal degradation

  4. Ubiquitin-activating enzyme is necessary for 17beta-estradiol-induced breast cancer cell proliferation and migration.

  5. Diminished ubiquitylation phenotype observed in enteropathogenic Escherichia coli infected cells corresponds to a strong reduction in the abundance of both Ube1 and Uba6 (show UBA6 Antibodies).

  6. Decrease in free ubiquitin levels under stress allows NEDD8 (show NEDD8 Antibodies) to be conjugated through Ube1.

  7. UBA1 knockdown impairs formation of ubiquitin conjugates at DNA double-strand breaks.

  8. Data show that largazole and ester/keto analogs inhibit ubiquitin E1 activation.

  9. Ubiquitin and UBE1 are upregulated in tic epilepsy.

  10. In conclusion, nUBE1L is a novel human E1 like gene highly expressed in adult testis, which plays key role in ubiquitin system, and accordingly influences spermatogenesis and male fertility.

Mouse (Murine) Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) interaction partners

  1. Inhibition of ubiquitin-activating enzyme E1 (Ube1) increases the levels of high- molecular weight mouse Htt (show HTT Antibodies) in relatively unaffected tissues, declining in the nuclear fraction with age.

  2. Dysregulation of UBA1 and subsequent ubiquitination pathways led to beta-catenin (show CTNNB1 Antibodies) accumulation in a model of spinal muscular atrophy.

  3. These data suggest that Cys (show DNAJC5 Antibodies)-278 can affect Ub charging through a change in the structural conformation of UBA1, not through direct interaction at the UBA1-Ub interface.

  4. biochemical and crystallographic characterization of the two half-domains and the crystal structure of the larger, second catalytic cysteine half-domain of mouse ubiquitin-activating enzyme

UBA1 Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.

Gene names and symbols associated with UBA1

  • ubiquitin activating enzyme E1 (uae1) antibody
  • ubiquitin-like modifier activating enzyme 1 (uba1-b) antibody
  • ubiquitin-like modifier activating enzyme 1 (uba1-a) antibody
  • ubiquitin-like modifier activating enzyme 1 (uba1) antibody
  • Ubiquitin-conjugating enzyme E1 (GL50803_4083) antibody
  • Ubiquitin-conjugating enzyme E1 (GL50803_10661) antibody
  • ubiquitin-like modifier activating enzyme 1 (UBA1) antibody
  • ubiquitin-like modifier activating enzyme 1 (Uba1) antibody
  • ubiquitin-like modifier activating enzyme 2 (Uba2) antibody
  • A1S9 antibody
  • A1S9T antibody
  • A1ST antibody
  • AA986091 antibody
  • AMCX1 antibody
  • Arx antibody
  • DDBDRAFT_0190927 antibody
  • DDBDRAFT_0220497 antibody
  • DDB_0190927 antibody
  • DDB_0220497 antibody
  • GXP1 antibody
  • POC20 antibody
  • Sae2 antibody
  • Sbx antibody
  • SMAX2 antibody
  • UBA1 antibody
  • UBA1A antibody
  • uba1b antibody
  • ube antibody
  • Ube-1 antibody
  • UBE1 antibody
  • Ube1x antibody
  • Ubl1a2 antibody
  • Uble1b antibody
  • wu:fa01e08 antibody
  • wu:fb30f01 antibody
  • wu:fi21c11 antibody
  • wu:fj14g11 antibody
  • zgc:66143 antibody

Protein level used designations for UBA1

ubiquitin-activating enzyme E1 , ubiquitin activating enzyme , fb30f01 , ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) , ubiquitin-like modifier-activating enzyme 1 , Ubiquitin-conjugating enzyme E1 , A1S9T and BN75 temperature sensitivity complementing , POC20 centriolar protein homolog , UBA1, ubiquitin-activating enzyme E1 homolog A , ubiquitin-activating enzyme E1, Chr X , SUMO-activating enzyme subunit 2 , SUMO1 activating enzyme subunit 2 , Sumo-1 activating enzyme subunit 2 , anthracycline-associated resistance ARX , ubiquitin-like 1 (sentrin) activating enzyme E1B , ubiquitin-like 1 (sentrin) activating enzyme subunit 2 , ubiquitin-like 1-activating enzyme E1B

GENE ID SPECIES
8617637 Dictyostelium discoideum AX4
379877 Xenopus laevis
398370 Xenopus laevis
406335 Danio rerio
5700601 Giardia lamblia ATCC 50803
5700939 Giardia lamblia ATCC 50803
7317 Homo sapiens
22201 Mus musculus
480896 Canis lupus familiaris
314432 Rattus norvegicus
282869 Bos taurus
100009225 Oryctolagus cuniculus
50995 Mus musculus
Selected quality suppliers for anti-UBA1 (UBA1) Antibodies
Did you look for something else?