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anti-Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3) Antibodies

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping UBA3 Proteins (12) and UBA3 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBA3 9039 Q8TBC4
UBA3 22200 Q8C878
UBA3 117553 Q99MI7
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Top anti-UBA3 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-UBA3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Pancreas Sample Type: 1. Human NT-2 cells (60ug)2. mouse brain extracts (80ug)Primary Antibody Dilution: 2ug/mlSecondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR BioscienceSecondary Antibody Dilution: 1: 20,000Image Submitted by: Yuzhi ChenUniversity of Arkansas for Medical Science  100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-UBE1 C-term Pab (ABIN387909) is used in Western blot to detect UBE1 in mouse brain tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Observed bind size: 52KD Anti- UBE1C Picoband antibody,IHC(P) IHC(P): Rat Testis Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB UBA3 antibody used at 5 ug/ml to detect target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details

UBA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-UBA3 Antibodies

  1. Human Polyclonal UBA3 Primary Antibody for IHC (p), WB - ABIN387909 : Bohnsack, Haas: Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN387909

  2. Chicken Polyclonal UBA3 Primary Antibody for IHC, WB - ABIN2784205 : Li, Santockyte, Shen, Tekle, Wang, Yang, Chock: A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers. in Archives of biochemistry and biophysics 2006 (PubMed)

  3. Human Polyclonal UBA3 Primary Antibody for EIA, IHC (p) - ABIN356593 : Osaka, Kawasaki, Aida, Saeki, Chiba, Kawashima, Tanaka, Kato: A new NEDD8-ligating system for cullin-4A. in Genes & development 1998 (PubMed)

More Antibodies against UBA3 Interaction Partners

Human Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3) interaction partners

  1. The study demonstrated that two mutations in UBA3 which were not previously reported confer MLN4924 resistance to MLN4924, a selective NEDD8 (show NEDD8 Antibodies)-activating enzyme inhibitor.

  2. E1 (NAE1 (show NAE1 Antibodies) and UBA3) and E2 (UBC12 (show ube2m Antibodies)) enzymes, as well as global NEDD8 (show NEDD8 Antibodies) conjugation, were upregulated in over 2/3 of human intrahepatic cholangiocarcinoma

  3. Report role for neddylation via Nedd8 (show NEDD8 Antibodies)-activating enzyme in the regulation of tumor angiogenesis.

  4. Demonstrated that Uba3-betaGD is an independently folded domain in solution and that residues involved in E2 binding are absent from the NMR spectrum, indicating that the E2-binding surface on Uba3-betaGD interconverts between multiple conformations.

  5. structure and mutational analysis of human APPBP1 (show NAE1 Antibodies)-UBA3, the heterodimeric E1 enzyme (show ENOPH1 Antibodies) for NEDD8 (show NEDD8 Antibodies)

  6. Conservation in the mechanism of Nedd8 (show NEDD8 Antibodies) activation by the human AppBp1 (show NAE1 Antibodies)-Uba3 heterodimer.

  7. Data report the structure of the quaternary complex between human APPBP1 (show NAE1 Antibodies)-UBA3, a heterodimeric E1, its ubl NEDD8 (show NEDD8 Antibodies), and ATP.

  8. crystal structure of a complex between the C-terminal domain from NEDD8 (show NEDD8 Antibodies)'s heterodimeric E1 (APPBP1 (show NAE1 Antibodies)-UBA3) and the catalytic core domain of NEDD8 (show NEDD8 Antibodies)'s E2 (Ubc12 (show ube2m Antibodies))

  9. X-ray crystallographic analysis of APPBP1 (show NAE1 Antibodies)-UBA3-NEDD8 (show NEDD8 Antibodies) shows that APPBP1 (show NAE1 Antibodies)-UBA3's preference for NEDD8 (show NEDD8 Antibodies)'s Ala72 appears to be indirect, due to proper positioning of UBA3's Arg190.

UBA3 Antigen Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with UBA3

  • ubiquitin-like modifier activating enzyme 3 (UBA3) antibody
  • ubiquitin-like modifier activating enzyme 3 (uba3) antibody
  • ubiquitin-like modifier activating enzyme 3 (Uba3) antibody
  • A830034N06Rik antibody
  • AI256736 antibody
  • AI848246 antibody
  • AW546539 antibody
  • hUBA3 antibody
  • ube1c antibody
  • wu:fb75e04 antibody
  • wu:fc37b11 antibody
  • zgc:55528 antibody

Protein level used designations for UBA3

ubiquitin-like modifier activating enzyme 3 , NEDD8-activating enzyme E1 catalytic subunit , NEDD8-activating enzyme E1 catalytic subunit-like , NEDD8-activating enzyme E1C , Nedd8-activating enzyme hUba3 , UBA3, ubiquitin-activating enzyme E1 homolog , ubiquitin-activating enzyme 3 , ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) , ubiquitin-activating enzyme E1C (homologous to yeast UBA3) , ubiquitin-like modifier-activating enzyme 3 , ubiquitin activating enzyme 3 , ubiquitin-activating enzyme E1C

GENE ID SPECIES
100011849 Monodelphis domestica
100196693 Salmo salar
100392131 Callithrix jacchus
100550920 Meleagris gallopavo
100566540 Anolis carolinensis
9039 Homo sapiens
22200 Mus musculus
406776 Danio rerio
734782 Xenopus laevis
426073 Gallus gallus
476560 Canis lupus familiaris
512647 Bos taurus
117553 Rattus norvegicus
Selected quality suppliers for anti-UBA3 (UBA3) Antibodies
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