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Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Proteins (UHRF2)

UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. Additionally we are shipping Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Antibodies (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UHRF2 27190 Q9UHF5
Rat UHRF2 UHRF2 309331  
Mouse UHRF2 UHRF2 109113 Q7TMI3
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Top Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UHRF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Interaction Partners

Human Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) interaction partners

  1. Studies indicate that interleukin 17 (show IL17A Proteins) (IL-17B (show IL17B Proteins))/interleukin 17 receptor B (IL-17RB) signaling is essential for pancreatic cancer malignancy.

  2. IL-17B (show IL17B Proteins)-IL-17RB signaling promotes pancreatic cancer malignancy.

  3. UHRF2 may contribute to the progression of colon carcinogenesis and function as a novel prognostic indicator after curative operation

  4. A hydrogen bond between the hydroxyl group of 5hmC and UHRF2-SRA (show SRA1 Proteins) is critical for their preferential binding.

  5. Results show that amplified signaling of interleukin-17 receptor B (IL-17RB) and its ligand IL-17B (show IL17B Proteins) promot tumorigenicity in breast cancer cells and impeded acinus (show ACIN1 Proteins) formation in immortalized normal mammary epithelial cells.

  6. IL-17B (show IL17B Proteins) can enhance the effects of TNF-alpha (show TNF Proteins) on the production of cytokines and chemokines that control immune cell trafficking and neutrophil homeostasis in the inflamed tissues.

  7. UHRF2 is a transcriptional target of E2F (show E2F1 Proteins), that it directly interacts with E2F1 (show E2F1 Proteins).

  8. IL-17A (show IL17A Proteins), IL-17B (show IL17B Proteins), IL-17F (show IL17F Proteins) and IL-23 (show IL23A Proteins) in systemic lupus erythematosus patients were examined and the correlation between levels of the investigated cytokines and VEGF (show VEGFA Proteins), PIGF (show PIGF Proteins), as well as number of endothelial cells, was investigated.

  9. UHRF2, the homolog of UHRF1 (show UHRF1 Proteins), interacts with N-methylpurine DNA glycosylase (MPG (show MPG Proteins)) in cancer cells.

  10. Low UHRF2 mRNA expression is associated with malignant glioma.

Mouse (Murine) Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) interaction partners

  1. Uhrf2 is highly expressed in aorta and aortic vascular smooth muscle cells.

  2. UHRF2 is not able to rescue the DNA methylation (show HELLS Proteins) defect in Uhrf1 (show UHRF1 Proteins) null mouse embryonic stem cells.

Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2) Protein Profile

Protein Summary

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

Gene names and symbols associated with UHRF2

  • interleukin 17B (IL17B)
  • Np95-like ring finger protein (uhrf2)
  • ubiquitin-like with PHD and ring finger domains 2 (UHRF2)
  • ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase (UHRF2)
  • ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase (Uhrf2)
  • ubiquitin-like, containing PHD and RING finger domains 2 (Uhrf2)
  • 2310065A22Rik protein
  • AI426270 protein
  • AW214556 protein
  • D130071B19Rik protein
  • IL-17B protein
  • IL-20 protein
  • Nirf protein
  • RNF107 protein
  • URF2 protein
  • ZCYTO7 protein

Protein level used designations for UHRF2

cytokine Zcyto7 , cytokine-like protein ZCYTO7 , interleukin 20 , interleukin-17 beta , interleukin-17B , interleukin-20 , neuronal interleukin-17 related factor , neuronal interleukin-17-related factor , ubiquitin-like with PHD and ring finger domains 2 , E3 ubiquitin-protein ligase UHRF2 , ubiquitin-like, containing PHD and RING finger domains, 2 , Np95-like ring finger protein , RING finger protein 107 , np95/ICBP90-like RING finger protein , nuclear protein 97 , nuclear zinc finger protein NP97 , ubiquitin-like PHD and RING finger domain-containing protein 2 , ubiquitin-like-containing PHD and RING finger domains protein 2 , ubiquitin-like, containing PHD and RING finger domains 2 , nuclear zinc finger protein Np97

GENE ID SPECIES
27190 Homo sapiens
100037238 Xenopus laevis
613759 Bos taurus
115426 Homo sapiens
474702 Canis lupus familiaris
309331 Rattus norvegicus
109113 Mus musculus
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