anti-Ubiquitin-Conjugating Enzyme E2B (UBE2B) Antibodies

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping UBE2B Proteins (24) and UBE2B Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBE2B 7320 P63146
UBE2B 22210 P63147
UBE2B 81816 P63149
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Top anti-UBE2B Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of UBE2B (arrow) using rabbit polyclonal UBE2B Antibody (E132) (ABIN388848). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the UBE2B gene. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of UBE2B expression in transfected 293T cell line by UBE2B monoclonal antibody (M06), clone 4C3. Lane 1: UBE2B transfected lysate(17.3 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 12% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using UBE2B, antibody at 1:500 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Mouse Rabbit Un-conjugated WB Western Blot: Ube2B Antibody [NBP2-20781] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 12% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Mouse Un-conjugated WB Western Blot: HR6B/UBE2B Antibody (1E11) [NBP2-46262] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UBE2B. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of UBE2B staining in rat lung formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the anti Western blot analysis of UBE2B expression in Jurkat (A), NIH3T3 (B), mouse heart (C), rat heart (D), rat brain (E) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat lung using UBE2B antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of UBE2B expression in transfected 293T cell line by UBE2B monoclonal antibody (M06), clone 4C3.Lane 1: UBE2B transfected lysate(17.3 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged UBE2B is approximately 3ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$430.00
Details

UBE2B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-UBE2B Antibodies

  1. Human Monoclonal UBE2B Primary Antibody for WB - ABIN393775 : Aston, Krausz, Laface, Ruiz-Castané, Carrell: Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent. in Human reproduction (Oxford, England) 2010 (PubMed)
    Show all 5 references for 393775

  2. Human Polyclonal UBE2B Primary Antibody for IHC (p), WB - ABIN388848 : Koken, Smit, Jaspers-Dekker, Oostra, Hagemeijer, Bootsma, Hoeijmakers: Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31. in Genomics 1992 (PubMed)
    Show all 3 references for 388848

  3. Human Polyclonal UBE2B Primary Antibody for EIA, IHC (p) - ABIN357490 : Koken, Reynolds, Jaspers-Dekker, Prakash, Prakash, Bootsma, Hoeijmakers: Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 3 references for 357490

More Antibodies against UBE2B Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2B (UBE2B) interaction partners

  1. These results point to an important role of the affinity between RNF4 (show RNF4 Antibodies) and its cognate RAD6B or UBCH5B (show UBE2D2 Antibodies) in governing the multiplicity of substrate ubiquitination.

  2. RAD6 promotes proteasome activity and nuclear translocation by enhancing the degradation of PSMF1 (show PSMF1 Antibodies) and the lamin B receptor (show LBR Antibodies).

  3. In conclusion, we reveal that miR (show MLXIP Antibodies)-455-5p expression is regulated by the TGF-beta (show TGFB1 Antibodies)-dependent pathway, which subsequently leads to UBE2B down-regulation and contributes to oral cancer tumourigenesis.

  4. Data show that the ubiquitin-conjugating enzyme E2 RAD6A/B-MDM2 ubiquitin ligase machinery regulates anti-silencing function 1A protein (ASF1A) degradation.

  5. A novel variant (Chr5.133706925 A > G) residing in the UBE2B gene promoter region confers a high risk for idiopathic azoospermia in a Chinese population.

  6. RAD6 physically interacts with heterochromatin protein 1alpha and ubiquitinates HP1alpha (show CBX5 Antibodies) at residue K154, thereby promoting heterochromatin protein 1alpha degradation through the autophagy pathway

  7. UBE2B mRNA alterations are associated with severe oligozoospermia in infertile men.

  8. RNF168 (show RNF168 Antibodies), in complex with RAD6A (show ube2a Antibodies) or RAD6B, is activated in the DNA-damage-induced protein ubiquitination cascade.

  9. UBE2B polymorphisms g.-293T>G, g.20016A>G and g.9157A>G are not associated with male infertility, and the GA haplotype is likely a protective factor for male fertility in Northeast Chinese men.

  10. beta-catenin (show CTNNB1 Antibodies) and Rad6B interacting regions, were identified.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2B (UBE2B) interaction partners

  1. RNF168 (show RNF168 Antibodies), in complex with RAD6A (show ube2a Antibodies) or RAD6B, is activated in the DNA-damage-induced protein ubiquitination cascade.

  2. These results suggest that Ube2b, as a direct androgen receptor transcriptional target in Sertoli cells, mediates the function of androgen recpetor in spermatogenesis by promoting H2A ubiquitylation.

  3. HR6B represses major satellite repeat transcription in spermatocytes, and functions in the maintenance of X chromosome silencing in spermatocytes and spermatids.

  4. The present findings reveal a specific requirement for the ubiquitin-conjugating activity of HR6B in relation to dynamic aspects of the synaptonemal complex and meiotic recombination in spermatocytes.

  5. Ube2b deficient mice are shown to present male infertility and sperm head shape anomalies.

  6. HR6B exerts control over different histone modifications in spermatocytes and spermatids, and that this function contributes to the postmeiotic maintenance of X chromosome silencing.

UBE2B Antigen Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Gene names and symbols associated with UBE2B

  • Ubiquitin-conjugating enzyme E2 B (ube2b) antibody
  • zgc:55512 (zgc:55512) antibody
  • ubiquitin-conjugating enzyme E2B (RAD6 homolog) (ube2b) antibody
  • ubiquitin-conjugating enzyme E2B (ube2b) antibody
  • ubiquitin-conjugating enzyme E2B (UBE2B) antibody
  • ubiquitin-conjugating enzyme E2B (RAD6 homolog) (UBE2B) antibody
  • ubiquitin-conjugating enzyme E2B (Ube2b) antibody
  • 2610301N02Rik antibody
  • E2-14k antibody
  • E2-17kDa antibody
  • fc79h10 antibody
  • HHR6B antibody
  • HR6B antibody
  • mHR6B antibody
  • Rad6b antibody
  • UBC2 antibody
  • wu:fc79h10 antibody
  • zgc:100921 antibody

Protein level used designations for UBE2B

Ubiquitin-conjugating enzyme E2 B , ubiquitin-conjugating enzyme E2 B , ubiquitin-conjugating enzyme E2B (RAD6 homolog) , ubiquitin-conjugating enzyme E2 , E2 protein , RAD6 homolog B , ubiquitin carrier protein B , ubiquitin-conjugating enzyme E2-17 kDa , ubiquitin-protein ligase B , E214K , ubiquitin-conjugating enzyme E2B, RAD6 homology , E2(14k) , ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme E2(14k) , ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae) , ubiquitin-conjugating enzyme E2B, RAD6 homolog , HR6B , ubiquitin conjugating-protein

GENE ID SPECIES
100286422 Salmo salar
100301680 Oncorhynchus mykiss
325470 Danio rerio
437020 Danio rerio
448706 Xenopus (Silurana) tropicalis
462065 Pan troglodytes
474683 Canis lupus familiaris
710678 Macaca mulatta
100381250 Ovis aries
7320 Homo sapiens
22210 Mus musculus
81816 Rattus norvegicus
443745 Xenopus laevis
100513527 Sus scrofa
512207 Bos taurus
100009132 Oryctolagus cuniculus
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