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Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. Additionally we are shipping UBE2F Antibodies (60) and many more products for this protein.
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Human UBE2F Protein expressed in Escherichia coli (E. coli) - ABIN2181885
Monda, Scott, Miller, Lydeard, King, Harper, Bennett, Schulman: Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes. in Structure (London, England : 1993) 2013
Show all 2 references for ABIN2181885
Human UBE2F Protein expressed in Escherichia coli (E. coli) - ABIN1098321
Huang, Ayrault, Hunt, Taherbhoy, Duda, Scott, Borg, Neale, Murray, Roussel, Schulman: E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. in Molecular cell 2009
Show all 2 references for ABIN1098321
Distinct preferences of UBC12 (show ube2m Proteins) and UBE2F peptides for inhibiting different DCNLs, including the oncogenic DCNL1 (show DCUN1D1 Proteins).
Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5 (By similarity).
, NEDD8-conjugating enzyme UBE2F
, NEDD8 carrier protein UBE2F
, NEDD8 protein ligase UBE2F
, NEDD8-conjugating enzyme 2
, ubiquitin-conjugating enzyme E2 F