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UBE2W encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2W (Putative) Proteins (21) and many more products for this protein.
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Human Polyclonal UBE2W Primary Antibody for IHC (p), WB - ABIN657530
Markson, Kiel, Hyde, Brown, Charalabous, Bremm, Semple, Woodsmith, Duley, Salehi-Ashtiani, Vidal, Komander, Serrano, Lehner, Sanderson: Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. in Genome research 2009
TRIM5alpha requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription.
We show the ubequitin-conjugating enzyme (E2) Ube2w uses a unique mechanism to facilitate the specific ubiquitination of the alpha-amino group
Ube2w has novel enzymatic properties that direct ubiquitination of the N terminus of substrates
UBE2W regulates FANCD2 (show FANCD2 Antibodies) monoubiquitination by mechanisms different from UBE2T (show Ube2t Antibodies) and HRR6.
human Ubiquitin-conjugating enzyme (E2 (show UBE2D4 Antibodies)) is homologous to the Arabidopsis thaliana UBC-16 gene product and contains 2 nuclear localization signals
results establish that UBE2W is an important, albeit not essential, protein for early postnatal survival and normal functioning of multiple organ systems.
This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
probable ubiquitin-conjugating enzyme E2 W
, ubiquitin-conjugating enzyme E2 W-like
, ubiquitin-conjugating enzyme E2W (putative)
, Ubiquitin carrier protein W
, Ubiquitin-protein ligase W
, ubiquitin-conjugating enzyme E2 W
, putative ubiquitin-conjugating enzyme E2 W
, Probable ubiquitin-conjugating enzyme E2 W
, adaptor protein complex AP-1, sigma 1
, ubiquitin carrier protein W
, ubiquitin-protein ligase W
, ubiquitin-conjugating enzyme 16
, ubiquitin-conjugating enzyme 2W
, probable ubiquitin-conjugating enzyme E2 W-A
, ubiquitin carrier protein W-A
, ubiquitin-protein ligase W-A