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Modification of proteins with ubiquitin (UBB\; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). Additionally we are shipping UBA6 Proteins (6) and many more products for this protein.
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this study revealed a novel function of LMO2 (show LMO2 Antibodies) involving in the regulatory hierarchy of UBA6-USE1 (show Use1 Antibodies)-FAT10ylation pathway by targeting the E1 enzyme (show ENOPH1 Antibodies) UBA6.
Interstitial microdeletions including the chromosome band 4q13.2 and the UBA6 gene as possible causes of intellectual disability and behavior disorder.
Diminished ubiquitylation phenotype observed in enteropathogenic Escherichia coli infected cells corresponds to a strong reduction in the abundance of both Ube1 (show UBA1 Antibodies) and Uba6.
Data indicate the potential role of cytokine-induced FAT10 (show UBD Antibodies) expression in regulating Uba6 pathways.
UBE1L2 is a novel E1 enzyme specific for ubiquitin
Human Uba6 and Ube1 have distinct preferences for E2 charging in vitro, and their specificity depends in part on their C-terminal ubiquitin-fold domains, which recruit E2s
The identification of an E1-like protein, termed E1-L2, that activates both ubiquitin and another ubiquitin-like protein, FAT10 (show UBD Antibodies), is reported.
Ubiquitin-like modifier activating enzyme 6 activates not only ubiquitin, but also the ubiquitin-like modifier FAT10 (show UBD Antibodies)[review]
Uba6 and Use1 (show UBE2Z Antibodies) promote proteasomal turnover of Ube3a (show ube3a Antibodies) in mouse embryo fibroblasts (MEFs) and catalyze Ube3a (show ube3a Antibodies) ubiquitylation in vitro.
Modification of proteins with ubiquitin (UBB\; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007
UBA6, ubiquitin-activating enzyme E1
, monocyte protein 4
, ubiquitin-activating enzyme 6
, ubiquitin-activating enzyme E1-like 2
, ubiquitin-activating enzyme E1-like protein 2
, ubiquitin-like modifier-activating enzyme 6