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Unc-45 Homolog A (C. Elegans) Proteins (UNC45A)

UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR\; MIM 607311) and HSP90 (HSPCA\; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]\; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008].. Additionally we are shipping UNC45A Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UNC45A 55898 Q9H3U1
Mouse UNC45A UNC45A 101869 Q99KD5
Rat UNC45A UNC45A 308759 Q32PZ3
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Top UNC45A Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UNC45A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Unc-45 Homolog A (C. Elegans) (UNC45A) Interaction Partners

Zebrafish Unc-45 Homolog A (C. Elegans) (UNC45A) interaction partners

  1. There is no functional redundancy between Unc45a and Unc45b (show UNC45B Proteins) in vivo.

  2. The results are the first to ascribe a role for Unc45a, a putative myosin chaperone, in vertebrate development, and identify a novel mechanism by which an arteriovenous malformation can form.

Human Unc-45 Homolog A (C. Elegans) (UNC45A) interaction partners

  1. UNC-45A is a crucial component in regulating human NK cell cytoskeletal dynamics via promoting the formation of actomyosin complexes.

  2. Findings identify a novel centrosomal function for UNC45A and its role in cell proliferation and tumorigenesis.

  3. The authors found that UNC-45A is alternatively expressed at the mRNA and protein levels as two isoforms and that the two isoforms differ only by a proline-rich 15 (show PRR15 Proteins)-amino-acid sequence near the amino-terminus.

  4. GCUNC-45 is a novel modulator of progesterone receptor (show PGR Proteins) chaperoning by hsp90 (show HSP90 Proteins).

  5. elevated GC UNC-45 protein expression in ovarian carcinoma proliferation and metastasis.

  6. GCUNC45 is required for the normal cellular distribution of Hsp90beta (show HSP90AB1 Proteins), but not Hsp90alpha (show HSP90AA2 Proteins).

UNC45A Protein Profile

Protein Summary

UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR\; MIM 607311) and HSP90 (HSPCA\; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002

Gene names and symbols associated with UNC45A

  • unc-45 homolog A (C. elegans) (UNC45A)
  • unc-45 homolog A (unc45a)
  • unc-45 homolog A (C. elegans) (unc45a)
  • unc-45 homolog A (C. elegans) (Unc45a)
  • AW538196 protein
  • GC-UNC45 protein
  • GCUNC-45 protein
  • GCUNC45 protein
  • IRO039700 protein
  • MGC89261 protein
  • RGD1305357 protein
  • SMAP-1 protein
  • SMAP1 protein
  • zgc:112031 protein

Protein level used designations for UNC45A

unc-45 homolog A (C. elegans) , unc-45 homolog A , kus , kurzschluss , protein unc-45 homolog A , UNC-45A , general cell UNC45 , smooth muscle cell associated protein-1 , smooth muscle cell-associated protein 1 , SMAP-1 , stromal membrane-associated protein 1 , UNC45 homolog A

GENE ID SPECIES
415584 Gallus gallus
493552 Xenopus (Silurana) tropicalis
715579 Macaca mulatta
100053485 Equus caballus
100394962 Callithrix jacchus
100474388 Ailuropoda melanoleuca
100592331 Nomascus leucogenys
488743 Canis lupus familiaris
550364 Danio rerio
100151986 Sus scrofa
55898 Homo sapiens
535692 Bos taurus
101869 Mus musculus
308759 Rattus norvegicus
100174449 Pongo abelii
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