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predicted to have similarity to C. Additionally we are shipping ULK1 Proteins (8) and many more products for this protein.
Showing 10 out of 239 products:
Human Polyclonal ULK1 Primary Antibody for DB - ABIN1881980
Mercer, Kaliappan, Dennis: A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy. in Autophagy 2009
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Human Polyclonal ULK1 Primary Antibody for DB - ABIN1881981
Ganley, Lam, Wang, Ding, Chen, Jiang: ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. in The Journal of biological chemistry 2009
Show all 4 references for ABIN1881981
Human Polyclonal ULK1 Primary Antibody for DB - ABIN1881978
Jung, Jun, Ro, Kim, Otto, Cao, Kundu, Kim: ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. in Molecular biology of the cell 2009
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Human Polyclonal ULK1 Primary Antibody for DB, IF - ABIN1881979
Pontén, Westermark: Properties of human malignant glioma cells in vitro. in Medical biology 1978
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Human Polyclonal ULK1 Primary Antibody for EIA, WB - ABIN1449620
Jiang, Li, Zhu, Wu, Tang, Li, Feng, Deng, Li, Luo, Zhang, Qin, Wang, Jia, Zhu: Intensive expression of UNC-51-like kinase 1 is a novel biomarker of poor prognosis in patients with esophageal squamous cell carcinoma. in Cancer science 2011
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Human Polyclonal ULK1 Primary Antibody for IF (p), IHC (p) - ABIN701440
Song, Kou, Zou, Gao, Zeng, Xie: Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens. in Neurochemistry international 2013
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Human Polyclonal ULK1 Primary Antibody for EIA, FACS - ABIN955448
Greenman, Stephens, Smith, Dalgliesh, Hunter, Bignell, Davies, Teague, Butler, Stevens, Edkins, OMeara, Vastrik, Schmidt, Avis, Barthorpe, Bhamra, Buck, Choudhury, Clements, Cole, Dicks, Forbes, Gray et al.: Patterns of somatic mutation in human cancer genomes. ... in Nature 2007
These results define a key molecular event for the starvation-induced activation of the ATG14-containing PtdIns3K complex by ULK1.
Knockdown of either ULK1 or DLP1 (show DNM1L Antibodies) expression with shRNAs suppresses LRRK2 (show LRRK2 Antibodies) G2019S expression-induced mitochondrial clearance, suggesting that LRRK2 (show LRRK2 Antibodies) G2019S expression induces mitochondrial fission through DLP1 (show DNM1L Antibodies) followed by mitophagy via an ULK1 dependent pathway.
Of several factors examined, bone metastasis, liver metastasis, and ULK1 expression were shown to have significant effects on the response to mTOR (show FRAP1 Antibodies) inhibitors.
ULK1 could inhibit p70S6K (show RPS6KB1 Antibodies) in starvation-induced autophagy, and further identified that miR (show MLXIP Antibodies)-4487 and miR (show MLXIP Antibodies)-595 were novel ULK1 target miRNAs
Structure of the human Atg13 (show ATG13 Antibodies)-Atg101 (show C12orf44 Antibodies) HORMA heterodimer in the ULK1 complex that controls autophagy has been described.
MUL1 (show MUL1 Antibodies) ubiquitinates ULK1 and regulates selenite-induced mitophagy
the inhibition of deubiquitinases by the compound WP1130 leads to increased ULK1 ubiquitination, the transfer of ULK1 to aggresomes, and the inhibition of ULK1 activity.
ROS (show ROS1 Antibodies)-AMPK (show PRKAA1 Antibodies)-ULK1 mechanism that couples T3-induced mitochondrial turnover with activity, wherein mitophagy is necessary not only for removing damaged mitochondria but also for sustaining efficient OXPHOS
Study identifies a key role of Cul3 (show CUL3 Antibodies)-KLHL20 (show KLHL20 Antibodies) in autophagy termination by controlling autophagy-dependent turnover of ULK1 and VPS34 (show PIK3C3 Antibodies) complex subunits and reveals the pathophysiological functions of this autophagy termination mechanism.
Findings highlight a cytoprotective role of p32 (show C1QBP Antibodies) under starvation conditions by regulating ULK1 stability, and uncover a crucial role of the p32 (show C1QBP Antibodies)-ULK1-autophagy axis in coordinating stress response, cell survival and mitochondrial homeostasis.
By enhancing PARP1 (show PARP1 Antibodies) activity, ULK1 contributes to ATP depletion and death of H2O2-treated cells.
autophagy can be executed by mechanisms that are dependent or independent of the ULK1/2-ATG13 (show ATG13 Antibodies) interaction.
MiR-17-5p may be able to arrest the maturation of mycobacterial phagosomes in part by targeting ULK1, subsequently reduces the ability of host cells to kill intracellular Camette-Guerin bacillus.
Concurrent mTORC1 inactivation and PP2A (show PPP2R2B Antibodies)-B55alpha (show PPP2R2A Antibodies) stimulation fuel ULK1-dependent autophagy.
AnxA2 (show ANXA2 Antibodies) regulates autophagy, thereby contributing to host immunity against bacteria through the Akt1 (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies)-ULK1/2 signaling pathway
Nitric oxide also stabilized an autophagy-related protein unc-51 like kinase (ULK1), but did not restore SIRT1 (show SIRT1 Antibodies) protein levels in ULK1-siRNA-treated cells or in mouse embryonic fibroblasts (MEF) from Ulk1-/- mice.
Ulk1-dependent Atg5-independent macroautophagy is the dominant process of mitochondrial clearance from fetal definitive reticulocytes.
predicted to have similarity to C. elegans serine/threonine kinase UNC-51
unc-51-like kinase 1 (C. elegans)
, serine/threonine-protein kinase ULK1
, unc-51-like kinase 1
, ATG1 autophagy related 1 homolog
, autophagy-related protein 1 homolog
, serine/threonine-protein kinase Unc51.1