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predicted to have similarity to C. Additionally we are shipping ULK1 Antibodies (225) and ULK1 Proteins (8) and many more products for this protein.
Of several factors examined, bone metastasis, liver metastasis, and ULK1 expression were shown to have significant effects on the response to mTOR (show FRAP1 ELISA Kits) inhibitors.
ULK1 could inhibit p70S6K (show RPS6KB1 ELISA Kits) in starvation-induced autophagy, and further identified that miR (show MLXIP ELISA Kits)-4487 and miR (show MLXIP ELISA Kits)-595 were novel ULK1 target miRNAs
Structure of the human Atg13 (show ATG13 ELISA Kits)-Atg101 (show C12orf44 ELISA Kits) HORMA heterodimer in the ULK1 complex that controls autophagy has been described.
MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy
the inhibition of deubiquitinases by the compound WP1130 leads to increased ULK1 ubiquitination, the transfer of ULK1 to aggresomes, and the inhibition of ULK1 activity.
ROS (show ROS1 ELISA Kits)-AMPK (show PRKAA1 ELISA Kits)-ULK1 mechanism that couples T3-induced mitochondrial turnover with activity, wherein mitophagy is necessary not only for removing damaged mitochondria but also for sustaining efficient OXPHOS
Study identifies a key role of Cul3 (show CUL3 ELISA Kits)-KLHL20 (show KLHL20 ELISA Kits) in autophagy termination by controlling autophagy-dependent turnover of ULK1 and VPS34 (show PIK3C3 ELISA Kits) complex subunits and reveals the pathophysiological functions of this autophagy termination mechanism.
Findings highlight a cytoprotective role of p32 (show C1QBP ELISA Kits) under starvation conditions by regulating ULK1 stability, and uncover a crucial role of the p32 (show C1QBP ELISA Kits)-ULK1-autophagy axis in coordinating stress response, cell survival and mitochondrial homeostasis.
Concurrent mTORC1 inactivation and PP2A (show PPP2R4 ELISA Kits)-B55alpha (show PPP2R2A ELISA Kits) stimulation fuel ULK1-dependent autophagy.
ULK1-mediated autophagy has a role in retinoic acid-induced IgG production in TLR9 (show TLR9 ELISA Kits)-activated human primary B cells
autophagy can be executed by mechanisms that are dependent or independent of the ULK1/2-ATG13 (show ATG13 ELISA Kits) interaction.
MiR-17-5p may be able to arrest the maturation of mycobacterial phagosomes in part by targeting ULK1, subsequently reduces the ability of host cells to kill intracellular Camette-Guerin bacillus.
Concurrent mTORC1 inactivation and PP2A-B55alpha (show PPP2R2A ELISA Kits) stimulation fuel ULK1-dependent autophagy.
AnxA2 (show ANXA2 ELISA Kits) regulates autophagy, thereby contributing to host immunity against bacteria through the Akt1 (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits)-ULK1/2 signaling pathway
Nitric oxide also stabilized an autophagy-related protein unc-51 like kinase (ULK1), but did not restore SIRT1 (show SIRT1 ELISA Kits) protein levels in ULK1-siRNA-treated cells or in mouse embryonic fibroblasts (MEF) from Ulk1-/- mice.
Ulk1-dependent Atg5-independent macroautophagy is the dominant process of mitochondrial clearance from fetal definitive reticulocytes.
ULK1 knockdown increased neuronal cell viability, and enhanced S6k1 (show RPS6KB1 ELISA Kits) phosphorylation in a dopaminergic neuron model of Parkinson's disease
this study identifies ULK1 as a new p62 Ser403 kinase and establishes Sestrin2 as a promoter of ULK1-mediated p62 phosphorylation.
predicted to have similarity to C. elegans serine/threonine kinase UNC-51
unc-51-like kinase 1 (C. elegans)
, serine/threonine-protein kinase ULK1
, unc-51-like kinase 1
, ATG1 autophagy related 1 homolog
, autophagy-related protein 1 homolog
, serine/threonine-protein kinase Unc51.1