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Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Additionally we are shipping Unc-51-Like Kinase 3 (C. Elegans) Antibodies (124) and many more products for this protein.
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Structural and biochemical studies reveal an unusually tight interaction between ULK3 and IST1 (show IST1 Proteins), an ESCRT-III subunit required for cytokinetic abscission.
First named and identified as protein kinase of the ULK family
Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog (show SHH Proteins) signaling pathway.
serine/threonine kinase (show TLK2 Proteins) ULK3 is involved in the SHH (show SHH Proteins) pathway as a positive regulator of GLI (show GLI1 Proteins) proteins
Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator autophagy (By similarity).
unc-51-like kinase 3 (C. elegans)
, serine/threonine-protein kinase ULK3
, serine/threonine-protein kinase ULK3-like
, unc-51-like kinase 3
, Serine/threonine-protein kinase ULK3
, hypothetical protein