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anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) Antibodies

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Additionally we are shipping UCP2 Kits (34) and UCP2 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UCP2 7351 P55851
UCP2 22228 P70406
UCP2 54315 P56500
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Top anti-UCP2 Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human endometrium labeled with Anti-UCP-2 Polyclonal Antibody, Unconjugated (ABIN675428) at 1:400 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with UCP2 antibody ABIN239858 at 1:50 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with UCP2 antibody ABIN461943 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Lung (formalin-fixed, paraffin-embedded) stained with UCP2 antibody ABIN461943 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated BCA 50 μL Log in to see 10 to 12 Days
$81.53
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$737.13
Details
Human Rabbit Un-conjugated IHC, WB 0.05 mL Log in to see 2 to 3 Days
$481.25
Details
Mouse Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$737.13
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details

UCP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-UCP2 Antibodies

  1. Human Polyclonal UCP2 Primary Antibody for BCA - ABIN2666219 : Pierrat, Ito, Hinz, Simonen, Erdmann, Chiesi, Heim: Uncoupling proteins 2 and 3 interact with members of the 14.3.3 family. in European journal of biochemistry / FEBS 2000 (PubMed)
    Show all 4 references for ABIN2666219

  2. Human Polyclonal UCP2 Primary Antibody for IF (p), IHC (p) - ABIN675428 : Chuang, Lin, Huang, Chang, Liou, Chen, Chang, Chan et al.: Peroxisome proliferator-activated receptors ?/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status ... in Journal of neuroinflammation 2012 (PubMed)

More Antibodies against UCP2 Interaction Partners

Zebrafish Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. except for reduced lipid peroxidation, we did not observe any significant reactive oxygen species reduction associated with increased Ucp2 activation in cold-exposed group.

Human Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. Estrogens may increase mitochondrial reactive oxygen species production by repressing uncoupling proteins including UCP2.

  2. UCP2 as a selective modulator of single channel MCU dependent mitochondrial Ca2 (show CA2 Antibodies)+ inward current.

  3. GTPBP3 (show GTPBP3 Antibodies) plays a role in the regulation of UCP2 protein through AMPK (show PRKAA1 Antibodies) signaling.

  4. We conclude that UCP2 neither mediates palmitate-induced mitochondrial ROS (show ROS1 Antibodies) generation and the associated cell loss, nor protects against these deleterious effects. Instead, UCP2 dampens palmitoleate protection against palmitate toxicity.

  5. UCP2 is expressed in human cumulus cells.

  6. Higher UCP2 expression corresponded with a poorer prognosis in breast cancer patients.

  7. Data reported here suggest that the UCP2 -866A/55Val/Ins (show INS Antibodies) haplotype is associated with an increased risk for DKD and with a lower eGFR (show EGFR Antibodies) in T2DM patients

  8. Dissipation of the proton gradient by Ucp2 is not the only determinant of the phagocytic capacity and that anion transfer or nucleotide binding by Ucp2 is also essential for Ucp2-mediated engulfment of apoptotic cells.

  9. ectopic overexpression of UCP2 in a HCC (show FAM126A Antibodies) cell line with low endogenous UCP2 expression, HLE (show ELANE Antibodies), significantly decreased mitochondrial superoxide induction by the anti-cancer drug GEM (show GEM Antibodies).

  10. exogenous expression of miR133a or knockdown of UCP-2 in MCF-7/Dox cells can sensitize their reaction to the treatment of Doxorubicin

Mouse (Murine) Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. Study shows that glucose load results in mitochondrial fission and reduced reactive oxygen species in ventromedial nucleus of the hypothalamus neurons mediated by dynamin (show DNM1 Antibodies)-related peptide 1 (DRP1 (show CRMP1 Antibodies)) under the control of uncoupling protein 2 (UCP2).

  2. UCP2 modulating role in mitochondrial calcium uptake

  3. Blocking UCP2 expression attenuates cardiac hypertrophy induced by pressure overload

  4. UCP2 knockout suppresses mouse skin carcinogenesis.

  5. A newly identified functional variant (rs1626521) in UCP-3 (show UCP3 Antibodies) affects postprandial gastric functions and satiety and may contribute to weight gain and alter human mitochondrial function.

  6. while the lack of UCP2 has no acute effect on body temperature, UCP2 may inhibit rapid improvements in defense against cold, in contrast to UCP1 (show UCP1 Antibodies), whose main function is to promote thermogenesis.

  7. high UCP2 levels allow better utilization of fatty acid oxidation resulting in a beneficial effect on mitochondrial function in heart, postponing systemic lactic acidosis and resulting in longer lifespan in these mice.

  8. Results suggest that hippocampal UCP2 is essential for cognitive function and the resistance to anxiety of mice, but not required for the beneficial effects of exercise

  9. Free fatty acid recognizes UCP2 at a peripheral site via electrostatic interaction. Flipping ionized fatty acid by UCP2 is required for UCP2-mediated H+ transport in mitochondria.

  10. long-term exposure to CT-1 (show CTF1 Antibodies)-CP could lead to the alteration in the expression of sarcomeric alpha-actin (show ACTA2 Antibodies), alpha-actinin (show ACTN1 Antibodies) and mitochondrial UCP2.

Pig (Porcine) Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. Despite patent grafts, revascularized hibernating myocardium demonstrates a submaximal response to dobutamine infusion and increased mitochondrial UCP-2 expression.

  2. Seven deletion polymorphisms were covered in introns of linkage genes of UCP2 and UCP3 (show UCP3 Antibodies), showing that UCPs have conservation and genetic reliability.

  3. The in vivo data indicate that beta-adrenergic agonists may function in regulating UCP2 and UCP3 (show UCP3 Antibodies) expression in selected muscles.

Cow (Bovine) Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) interaction partners

  1. UCPs do have uncoupling properties when expressed in mitochondria but that uncoupling by UCP1 (show UCP1 Antibodies) or UCP2 does not prevent acute substrate-driven endothelial cell superoxide as effluxed from mitochondria respiring in vitro.

  2. A study evaluating the relationships of uncoupling protein 2 and 3 expression, SNP of mitochondrial DNA, and residual feed intake (RFI (show RNF34 Antibodies)) in Angus steers selected to have high or low RFI (show RNF34 Antibodies) is presented.

  3. These results suggest that UCP2 play an important role of lipid and energy metabolism in mammary epithelial cells.

UCP2 Antigen Profile

Protein Summary

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.

Gene names and symbols associated with UCP2

  • mitochondrial uncoupling protein 2 (PTRG_09289) antibody
  • uncoupling protein 2 (mitochondrial, proton carrier) (UCP2) antibody
  • mitochondrial uncoupling protein 2 (LOC100282746) antibody
  • uncoupling protein 2 (ucp2) antibody
  • uncoupling protein 2 (mitochondrial, proton carrier) (TEgg068n20.1) antibody
  • uncoupling protein 2 (UCP2) antibody
  • uncoupling protein 2 (LOC100534553) antibody
  • uncoupling protein 2 (mitochondrial, proton carrier) (Ucp2) antibody
  • ATUCP2 antibody
  • BMIQ4 antibody
  • cb74 antibody
  • DKFZp470P1633 antibody
  • K19M22.21 antibody
  • K19M22_21 antibody
  • MGC53319 antibody
  • MGC75881 antibody
  • Slc25a8 antibody
  • ucp2 antibody
  • UCPH antibody
  • uncoupling protein 2 antibody

Protein level used designations for UCP2

mitochondrial uncoupling protein 2 , uncoupling protein 2 (mitochondrial, proton carrier) , Mitochondrial uncoupling protein 2 , uncoupling protein 2 , UCP 2 , solute carrier family 25 member 8 , zUCP2 , UCPH , uncoupling protein 2, mitochondrial , uncoupling protein homolog , Uncoupling protein 2, mitochondrial

GENE ID SPECIES
6347579 Pyrenophora tritici-repentis Pt-1C-BFP
100173815 Pongo abelii
100282746 Zea mays
379915 Xenopus laevis
394786 Xenopus (Silurana) tropicalis
555812 Danio rerio
574198 Macaca mulatta
836014 Arabidopsis thaliana
100534553 Oreochromis niloticus
7351 Homo sapiens
22228 Mus musculus
397549 Sus scrofa
54315 Rattus norvegicus
281562 Bos taurus
403576 Canis lupus familiaris
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