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Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Additionally we are shipping UCP3 Kits (10) and and many more products for this protein.
Showing 10 out of 67 products:
Dog (Canine) Polyclonal UCP3 Primary Antibody for WB - ABIN151510
Mayrhofer, Krieger, Huttary, Chang, Grillari, Allmaier, Kerjaschki: Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis. in The American journal of pathology 2009
Show all 2 references for ABIN151510
genetic association studies in population in Spain: Data suggest that responses among obese patients (weight loss and changes in insulin (show INS Antibodies) resistance/cardiovascular risk factors) to high protein/low carbohydrate reducing diet varies according to a genetic polymorphism in the promoter region of UCP3 (-55CT, rs1800849).
Combined, our data suggest functional significance of UCP-3 for H/R resistance
UCP1 (show UCP1 Antibodies) and UCP3 expression is associated with lipid and carbohydrate oxidation in patients submitted to bariatric surgery.
UCP3 overexpression limits keratinocyte proliferation and tumorigenesis through inhibition of Akt (show AKT1 Antibodies).
Children with UCP-3 -55 T/T genotype had a significantly lower adjusted metabolic rate than the C allele carriers.
A newly identified functional variant (rs1626521) in UCP-3 affects postprandial gastric functions and satiety and may contribute to weight gain and alter human mitochondrial function
Genotype and allele distributions of UCP1 (show UCP1 Antibodies), UCP2 (show UCP2 Antibodies) and UCP3 polymorphisms did not differ significantly between obese and non-obese Type 2 Diabetes Mellitus patients.[Meta-analysis]
The meta-analysis detected a significant association between the UCP2 (show UCP2 Antibodies)-866G/A, Ins (show INS Antibodies)/Del, Ala55Val and UCP3-55C/T polymorphisms and BMI mean differences.
UCP3 genotype prevailed in the women of besieged Leningrad compared to relevant control groups of the persons of the same age who did not suffered hungry disaster.
Studied the impact of SNPs in/near UCP3 and RPTOR (show RPTOR Antibodies) on obesity-related traits.
We found increased mRNA expression of PDK4 (show PDK4 Antibodies) and UCP3, which are known to be upregulated after exercise and regulated by PGC-1alpha (show PPARGC1A Antibodies) after lactate administration.
suggest that VD3/VDR (show CYP27B1 Antibodies) inhibits weight gain by activating UCP3 in the muscles.
the protective effect of PPARalpha (show PPARA Antibodies) activation against cardiac ischemia-reperfusion injury in terms of the expression of uncoupling protein (UCP (show UCP1 Antibodies)), was investigated.
low 4-Hydroxy-2-nonenal (HNE (show ELANE Antibodies)) doses activate Nrf2 (show NFE2L2 Antibodies) in cardiomyocytes and provide the first evidence of Nrf2 (show NFE2L2 Antibodies) binding to the Ucp3 promoter in response to HNE (show ELANE Antibodies), leading to increased protein expression
The hydrophilic sequences within loop 2, and the matrix-localized hydrophilic domain of UCP3, were necessary for binding to Hax-1 (show HAX1 Antibodies) at the C-terminal domain, adjacent to the mitochondrial inner membrane.
abundance decreased even more in cold-acclimated UCP1 (show UCP1 Antibodies) knockout mice
regulatory mechanism by which insulin (show INS Antibodies) inhibits cardiac UCP3 expression through activation of the lipogenic factor SREBP-1 (show SREBF1 Antibodies).
Ischemia/reperfusion also increased UCP3 transcription, indicating potential for greater uncoupling.
Nrf2 (show NFE2L2 Antibodies) promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress.
The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain (show CAPN2 Antibodies)/HhaI, and UCP-3/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.
A study evaluating the relationships of uncoupling protein 2 (show UCP2 Antibodies) and 3 expression, SNP of mitochondrial DNA, and residual feed intake (RFI (show RNF34 Antibodies)) in Angus steers selected to have high or low RFI (show RNF34 Antibodies) is presented.
Association of pig UCP3 gene mutations and back fat thickness in the sixth and seventh rib.
Seven deletion polymorphisms were covered in introns of linkage genes of UCP2 (show UCP2 Antibodies) and UCP3, showing that UCPs have conservation and genetic reliability.
The in vivo data indicate that beta-adrenergic agonists may function in regulating UCP2 (show UCP2 Antibodies) and UCP3 expression in selected muscles.
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression\; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.
, mitochondrial uncoupling protein
, mitochondrial uncoupling protein 3
, uncoupling protein
, uncoupling protein 3 (mitochondrial, proton carrier)
, uncoupling protein UCP
, mitochondrial uncoupling protein 3-like
, solute carrier family 25 member 9
, UCP 3
, uncoupling protein 3, mitochondrial
, Uncoupling protein 3, mitochondrial