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Upper Zone of Growth Plate and Cartilage Matrix Associated Proteins (UCMA)

May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.. Additionally we are shipping UCMA Antibodies (27) and UCMA Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UCMA 221044 Q8WVF2
Mouse UCMA UCMA 68527 Q14BU0
UCMA 291312  
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Top UCMA Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast REACT_Sea bass His tag   1 mg Log in to see 56 to 66 Days
$2,196.33
Details
Yeast REACT_Bream His tag   1 mg Log in to see 56 to 66 Days
$2,196.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,209.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,212.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 5 Days
$522.50
Details

UCMA Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Rat (Rattus)

More Proteins for Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA) Interaction Partners

Zebrafish Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA) interaction partners

  1. Report a functional promoter for grp2 gene regulated by Sox9b, Sox10 (show SOX10 Proteins), Ets1 (show ETS1 Proteins) and Mef2ca (show MEF2C Proteins) as determined by in vitro assays. This was confirmed in vivo for Sox9b and Sox10 (show SOX10 Proteins).

  2. Knockdown of ucmaa leads to severe growth retardation and perturbance of skeletal development.

Human Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA) interaction partners

  1. The study demonstrates the involvement of GRP (show LSM4 Proteins) in the two major molecular processes affecting osteoarthritis: mineralization and inflammation of articular tissue.

  2. Data suggest that novel splice variants of GRP (show LSM4 Proteins)are expressed in cartilage and other tissues (i.e. GRP (show LSM4 Proteins)-F5, GRP- (show LSM4 Proteins)F6); GRP-F1 is predominant splice variant expressed in adult tissues particularly in cartilage of patients with osteoarthritis.

  3. full exon resequencing of DNA samples from 17 chronic kidney disease patients (stage 5) and 121 healthy controls in a Swsedish population; the 138Thr > Ser (show SIGLEC1 Proteins) polymorphism seems to be the only non-synonymous SNP found in the UCMA gene in a Swedish population

  4. Gla-rich protein (GRP) is a new vitamin K-dependent protein that can bind calcium through Gla (show NAT8 Proteins) residues.

  5. The present data strongly suggest an important function of Ucma in the early phase of chondrocyte differentiation.

  6. Ucma may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells

Mouse (Murine) Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA) interaction partners

  1. Data suggest that a novel splice variant of GRP is expressed in cartilage and other tissues (i.e. GRP-F7); GRP-F1 is predominant splice variant expressed in adult tissues.

  2. Considering that skeletal development in Ucma-deficient mice is not significantly impaired, protein expression in adult cartilage indicates that Ucma might be involved in skeletal homeostasis and in the mechanical properties of the skeleton

  3. Four alternative splicing variants derived from the mouse Ucma/GRP gene in chondrocytes were identified and their expression and subcellular localization during chondrogenesis was determined.

  4. The present data strongly suggest an important function of Ucma in the early phase of chondrocyte differentiation.

  5. Ucma may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells

UCMA Protein Profile

Protein Summary

May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.

Gene names and symbols associated with UCMA

  • upper zone of growth plate and cartilage matrix associated (UCMA)
  • upper zone of growth plate and cartilage matrix associated (ucma)
  • upper zone of growth plate and cartilage matrix associated a (ucmaa)
  • upper zone of growth plate and cartilage matrix associated (LOC100356479)
  • upper zone of growth plate and cartilage matrix associated (Ucma)
  • 1110017I16Rik protein
  • AW121955 protein
  • C10orf49 protein
  • Grp protein
  • GRP2 protein
  • RGD1308977 protein
  • ucma protein
  • zgc:162317 protein

Protein level used designations for UCMA

upper zone of growth plate and cartilage matrix associated , Gla-Rich Protein 2 , Grp-2 , unique cartilage matrix-associated protein , Gla-rich protein , upper zone of growth plate and cartilage matrix associated protein

GENE ID SPECIES
478002 Canis lupus familiaris
615924 Bos taurus
100037225 Xenopus laevis
100037325 Danio rerio
100069244 Equus caballus
100085343 Ornithorhynchus anatinus
100356479 Oryctolagus cuniculus
100528617 Ictalurus punctatus
221044 Homo sapiens
68527 Mus musculus
291312 Rattus norvegicus
Selected quality suppliers for UCMA Proteins (UCMA)
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