anti-Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) Antibodies

UBTF encodes a member of the HMG-box DNA-binding protein family. Additionally we are shipping Upstream Binding Transcription Factor, RNA Polymerase I Kits (4) and Upstream Binding Transcription Factor, RNA Polymerase I Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBTF 7343 P17480
UBTF 21429  
UBTF 25574 P25977
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Top anti-Upstream Binding Transcription Factor, RNA Polymerase I Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-UBTF Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit <br /> Target Name: Ubtf <br /> Sample Tissue: Rat Spleen lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa/Jurkat cells, using UBF1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using UBF1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa cells treated with calyculinA 50ng/ml 30', using UBF (Phospho-Ser484) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using UBF (Phospho-Ser484) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB UBTF Antibody (C-term) (ABIN656478) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the UBTF antibody detected the UBTF protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB UBTF Antibody (C-term) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the UBTF antibody detected the UBTF protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of UBF staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with Western blot analysis of UBF expression in Jurkat (A), rat muscle (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to UBTF on HepG2 cell (antibody concentration 10 µg/mL). UBTF monoclonal antibody (M03), clone 1A2 Western Blot analysis of UBTF expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$676.50
Details

UBTF Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Upstream Binding Transcription Factor, RNA Polymerase I Antibodies

  1. Human Monoclonal UBTF Primary Antibody for IF, IHC (p) - ABIN563329 : Østrup, Petrovicova, Strejcek, Morovic, Lucas-Hahn, Lemme, Petersen, Niemann, Laurincik, Maddox-Hyttel: Nuclear and nucleolar reprogramming during the first cell cycle in bovine nuclear transfer embryos. in Cloning and stem cells 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal UBTF Primary Antibody for ICC, IF - ABIN4364030 : Sobol, Yildirim, Philimonenko, Marášek, Castaño, Hozák: UBF complexes with phosphatidylinositol 4,5-bisphosphate in nucleolar organizer regions regardless of ongoing RNA polymerase I activity. in Nucleus (Austin, Tex.) 2014 (PubMed)

More Antibodies against Upstream Binding Transcription Factor, RNA Polymerase I Interaction Partners

Human Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) interaction partners

  1. Study demonstrated that HMG (show SSRP1 Antibodies) box 1, the linker region between the HMG (show SSRP1 Antibodies) boxes and C-terminal acidic region (AR), and the AR cooperatively regulate the nucleolar localization of UBF.

  2. In seven unrelated affected individuals, all suffering from developmental regression starting at 2.5-7 years, the authors identified a heterozygous variant, c.628G>A in UBTF, encoding p.Glu210Lys in UBF, which occurred de novo in all cases.

  3. RINT-1 (show RINT1 Antibodies) interacts with MSP58 (show MCRS1 Antibodies) and UBF within nucleoli and plays a role in ribosomal gene transcription.

  4. This study provides some compelling evidences in support of HBx-elicited and c-Myc (show MYC Antibodies)-mediated increase in UBF levels that abets oncogenic onslaught in hepatic cells by increasing rDNA transcription and ribosome biogenesis.

  5. These results suggest that UBF can inhibit gene expression from viral DNA prior to its replication.

  6. we have uncovered a novel role for UBTF1 and UBTF2 in maintaining genome stability through coordinating the expression of highly transcribed Pol I (UBTF1 activity) and Pol II genes (UBTF2 activity).

  7. p14ARF (show CDKN2A Antibodies) fails to prevent E7-mediated UBF1 phosphorylation, but could facilitate nucleolar pRb (show RB1 Antibodies) inactivation by targeting E7 to the nucleolus.

  8. PIP2 depletion reduces Pol I transcription.

  9. UBF is expressed widely by human multiple fetal tissue,s and the expression level is very high in HL-60 cells.

  10. Downregulation of RUNX2 (show RUNX2 Antibodies) expression reduces the localization of HDAC1 (show HDAC1 Antibodies) to the nucleolar periphery and also decreases the association between HDAC1 (show HDAC1 Antibodies) and UBF.

Mouse (Murine) Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) interaction partners

  1. UBF and Nopp140 (show NOLC1 Antibodies) dynamic redistribution between the two-cell and blastocyst stages (time of implantation) is correlated with morphological and structural modifications that occur in embryonic nucleolar compartments.

  2. inhibition of UBF function is a major factor in the cytotoxicity of cisplatin; its depletion selectively induces p53 (show TP53 Antibodies)-independent apoptotic death in transformed cells

  3. Loss of UBF also unexpectedly induced the formation in cells of a large sub-nuclear structure resembling the nucleolar precursor body (NPB (show NPB Antibodies)) of oocytes and early embryos.

  4. we have uncovered a novel role for UBTF1 and UBTF2 in maintaining genome stability through coordinating the expression of highly transcribed Pol I (UBTF1 activity) and Pol II genes (UBTF2 activity).

  5. UBF1 mutation (K352A, K352Q, and K352R) decreased rDNA transcriptional activity.

  6. augmented ribosome biogenesis occurs in UBF-dependent manner during increased protein synthesis induced by high glucose in glomerular epithelial cells that correlates with UBF activation and renal hypertrophy in rodents with type 1 and type 2 diabetes.

  7. increased UBF levels correlate with elevated pressure load and increased cardiac growth rates

  8. mTOR (show FRAP1 Antibodies) plays a critical role in the regulation of ribosome biogenesis via a mechanism that requires S6K1 (show RPS6KB1 Antibodies) activation and phosphorylation of UBF.

  9. effects of PES1 (show PES1 Antibodies) and UBF1 expression on the growth and differentiation of cell lines derived from 32D cells, an interleukin-3 (IL-3 (show IL-3 Antibodies))-dependent murine myeloid cell line

  10. Phosphatidylinositol 3-kinase subunit directly phosphorylates and activates UBF1, an exclusively nucleolar protein (show MCRS1 Antibodies).

Upstream Binding Transcription Factor, RNA Polymerase I (UBTF) Antigen Profile

Protein Summary

This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

Gene names and symbols associated with UBTF

  • upstream binding transcription factor, RNA polymerase I (ubtf) antibody
  • upstream binding transcription factor, RNA polymerase I (UBTF) antibody
  • upstream binding transcription factor, RNA polymerase I (Ubtf) antibody
  • A930005G04Rik antibody
  • NOR-90 antibody
  • si:dz180g5.3 antibody
  • Tcfubf antibody
  • ubf antibody
  • UBF-1 antibody
  • UBF1 antibody
  • UBTF antibody
  • wu:fj38c10 antibody
  • xUBF antibody

Protein level used designations for UBTF

upstream binding transcription factor, RNA polymerase I , nucleolar transcription factor 1-like , 90-kDa nucleolus organizer region autoantigen , autoantigen NOR-90 , nucleolar transcription factor 1 , UBF-1 , transcription factor UBF , upstream-binding factor 1

GENE ID SPECIES
368509 Danio rerio
454726 Pan troglodytes
497012 Bos taurus
100019759 Monodelphis domestica
100064724 Equus caballus
100135747 Xenopus (Silurana) tropicalis
100454637 Pongo abelii
100483006 Ailuropoda melanoleuca
100511403 Sus scrofa
100558152 Anolis carolinensis
7343 Homo sapiens
21429 Mus musculus
25574 Rattus norvegicus
480503 Canis lupus familiaris
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