Ureidopropionase, beta (UPB1) ELISA Kits

UPB1 encodes a protein that belongs to the CN hydrolase family. Additionally we are shipping UPB1 Antibodies (20) and UPB1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human UPB1 UPB1 51733 Q9UBR1
Anti-Mouse UPB1 UPB1 103149 Q8VC97
Anti-Rat UPB1 UPB1 116593 Q03248
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More ELISA Kits for UPB1 Interaction Partners

Human Ureidopropionase, beta (UPB1) interaction partners

  1. The c.977G>A (p.R326Q) is the most common mutation of the UPB1 gene in Chinese. The predicted incidence indicates that beta-ureidopropionase deficiency is significantly underdiagnosed in the Chinese population.

  2. This study reports the clinical, biochemical, and molecular analysis of a newly identified patient with beta-ureidopropionase deficiency and the effect of the first synonymous mutation in UBP1 affecting pre-mRNA splicing, using the minigene approach.

  3. analysis of UPB1 variants on 5-FU-related toxicity in the population of all analyzed patients revealed an association between the c.-80C>G (rs2070474) variant and gastrointestinal toxicity

  4. An altered homeostasis of beta-aminoisobutyric acid and/or increased oxidative stress might contribute to some of the clinical abnormalities encountered in patients with a beta (show SUCLA2 ELISA Kits)-ureidopropionase deficiency.

  5. analysis of the beta-ureidopropionase gene (UPB1) of the first 4 patients presenting with a complete enzyme deficiency, revealed the presence of 2 splice-site mutations (IVS1-2A>G and IVS8-1G>A) and one missense mutation (A85E)

Mouse (Murine) Ureidopropionase, beta (UPB1) interaction partners

UPB1 Antigen Profile

Antigen Summary

This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

Gene names and symbols associated with UPB1

  • ureidopropionase, beta (upb1) antibody
  • ureidopropionase, beta (UPB1) antibody
  • Protein UPB-1 (upb-1) antibody
  • ureidopropionase, beta (Upb1) antibody
  • AI195023 antibody
  • Bup1 antibody
  • MGC82230 antibody
  • wu:fb69e03 antibody
  • zgc:64020 antibody

Protein level used designations for UPB1

ureidopropionase, beta , beta-ureidopropionase , beta-alanine synthase , N-carbamoyl-beta-alanine amidohydrolase , beta-ureidopropionase-like , BUP-1 , n-carbamoyl-beta-alanine amidohydrolase

447326 Xenopus laevis
504557 Bos taurus
707752 Macaca mulatta
747532 Pan troglodytes
100013001 Monodelphis domestica
100053177 Equus caballus
100145317 Xenopus (Silurana) tropicalis
100155919 Sus scrofa
100172385 Pongo abelii
100357276 Oryctolagus cuniculus
100478175 Ailuropoda melanoleuca
100597745 Nomascus leucogenys
174040 Caenorhabditis elegans
322660 Danio rerio
416949 Gallus gallus
51733 Homo sapiens
486398 Canis lupus familiaris
103149 Mus musculus
116593 Rattus norvegicus
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