You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Uridine Phosphorylase 1 (UPP1) Antibodies

The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP\; EC 2.4.2.3) and thymidine phosphorylase (TP\; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Additionally we are shipping UPP1 Kits (11) and UPP1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UPP1 7378 Q16831
UPP1 22271 P52624
UPP1 289801  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-UPP1 Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-UPP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-UPP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB UPP1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to UPP1 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged UPP1 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details

UPP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
, ,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-UPP1 Antibodies

  1. Chicken Polyclonal UPP1 Primary Antibody for WB - ABIN2777157 : Temmink, de Bruin, Laan, Turksma, Cricca, Masterson, Noordhuis, Peters: The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells. in The international journal of biochemistry & cell biology 2006 (PubMed)

More Antibodies against UPP1 Interaction Partners

Human Uridine Phosphorylase 1 (UPP1) interaction partners

  1. Data show that enhanced cytotoxicity of 5-FU by bFGF (show FGF2 Antibodies) through modulating the expression of UPP1 at the transcription level.

  2. The expression level of UPase gene may be an independent prognostic marker in human breast carcinoma

  3. Characterization of the promoter region of UPase has indicated a direct regulation of its expression by the tumor suppressor gene p53 (show TP53 Antibodies). Review.

  4. Thymidine phosphorylase (show TYMP Antibodies) and uridine phosphorylase were both responsible for converting 5'dFUrd/5FU into 5FU/FUrd, respectively

  5. The presented structures confirm that hUPP1 (show PTP4A2 Antibodies) is dimeric. They also reveal the mechanism by which 5-benzylacyclouridine engages the active site of the protein and disables the enzyme by locking the protein in a closed conformation.

Mouse (Murine) Uridine Phosphorylase 1 (UPP1) interaction partners

  1. Importance of UPase in the activation of fluoropyrimidines, the effect of uridine in protecting normal tissues, and the role for tumor-specific modulation of the phosphorolytic activity in 5-FU or capecitabine-based chemotherapy.

  2. Data show that enhanced cytotoxicity of 5-FU by bFGF (show FGF2 Antibodies) through modulating the expression of UPP1 at the transcription level.

  3. Targeted deletion of both thymidine phosphorylase (show TYMP Antibodies) and uridine phosphorylase and consequent disorders in mice.

  4. UPase is a critical enzyme in the regulation of uridine homeostasis and pyrimidine nucleotide metabolism, and 5-fluorouracil activity

  5. Taken together, the present study provides the first evidence that uridine protects neurons against ischemic insult-induced neuronal death, possibly through the action of UPase.

  6. Thymidine phosphorylase (show TYMP Antibodies) and UPP1 double knockout mice showed increased thymidine and deoxyuridine in tissues and developed encephalopathy.

UPP1 Antigen Profile

Protein Summary

The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP\; EC 2.4.2.3) and thymidine phosphorylase (TP\; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995

Gene names and symbols associated with UPP1

  • uridine phosphorylase 1 (upp1) antibody
  • uridine phosphorylase 1 (udp_1) antibody
  • uridine phosphorylase 1 (Tsp_02326) antibody
  • Uridine phosphorylase 1 (upp1) antibody
  • uridine phosphorylase 1 (LOC100224766) antibody
  • uridine phosphorylase 1 (UPP1) antibody
  • uridine phosphorylase 1 (Upp1) antibody
  • uridine phosphorylase 1-like (LOC100625277) antibody
  • uridine phosphorylase 1-like (LOC100357952) antibody
  • AI325217 antibody
  • im:6911242 antibody
  • UdRPase antibody
  • Up antibody
  • UPase antibody
  • Upp antibody
  • upp1 antibody
  • zgc:110755 antibody

Protein level used designations for UPP1

uridine phosphorylase 1 , Uridine phosphorylase 1 , UPase 1 , urdPase 1

GENE ID SPECIES
496532 Xenopus (Silurana) tropicalis
3703440 Natronomonas pharaonis DSM 2160
10907966 Trichinella spiralis
100196719 Salmo salar
100224766 Taeniopygia guttata
100528868 Ictalurus punctatus
7378 Homo sapiens
503707 Danio rerio
420942 Gallus gallus
515029 Bos taurus
22271 Mus musculus
289801 Rattus norvegicus
100727838 Cavia porcellus
100625277 Sus scrofa
100357952 Oryctolagus cuniculus
Selected quality suppliers for anti-UPP1 (UPP1) Antibodies
Did you look for something else?