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The protein encoded by UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping Uroplakin 1B Proteins (3) and many more products for this protein.
Showing 10 out of 52 products:
Human Polyclonal UPK1B Primary Antibody for EIA, WB - ABIN955481
Tu, Sun, Kreibich: Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum. in Molecular biology of the cell 2002
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Human Monoclonal UPK1B Primary Antibody for ELISA, WB - ABIN394458
Kalma, Granot, Gnainsky, Or, Czernobilsky, Dekel, Barash: Endometrial biopsy-induced gene modulation: first evidence for the expression of bladder-transmembranal uroplakin Ib in human endometrium. in Fertility and sterility 2009
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Human Polyclonal UPK1B Primary Antibody for IHC (p), WB - ABIN1450060
Yu, Lin, Wu, Sun: Uroplakins Ia and Ib, two major differentiation products of bladder epithelium, belong to a family of four transmembrane domain (4TM) proteins. in The Journal of cell biology 1994
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Human Polyclonal UPK1B Primary Antibody for FACS, IHC (p) - ABIN955480
Cowled, Kanter, Leonardos, Jackson: Uroplakin Ib gene transcription in urothelial tumor cells is regulated by CpG methylation. in Neoplasia (New York, N.Y.) 2005
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Urine UPIb levels may be useful for predicting the risk of recurrent urinary tract infections in patients diagnosed with their first UTI (show AMBP Antibodies) and may also be considered as a noninvasive screening test for vesicoureteral reflux.
established the genomic organization of the UPIb gene
Loss of uroplakin Ib expression is associated with bladder carcinomas
Loss of uroplakin Ib expression by CpG methylation of Sp1/NFkappaB-binding motifs within the proximal promoter is associated with urothelial tumors
The biopsy-induced increase in the expression of UPIb and other genes encoding membrane proteins supports the possible importance of the membrane structure and stability during implantation.
Upk1b expression is critical for urothelial plaque stability, maturation, differentiation, and homeostasis of urothelium. Report CAKUT in Upk1b knockout mice.
The despites a lower level of expression, UPIb maintain its plaque association in urothelial preneoplastic lesions.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.
, uroplakin 1b
, uroplakin Ib
, uroplakin IB