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UPK3A encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Additionally we are shipping Uroplakin 3A Kits (6) and Uroplakin 3A Proteins (6) and many more products for this protein.
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Cow (Bovine) Monoclonal Uroplakin 3A Primary Antibody for IHC (p), WB - ABIN112250
Hu, Deng, Liang, Hu, Auerbach, Shapiro, Wu, Kachar, Sun: Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux. in The Journal of cell biology 2000
Show all 8 references for ABIN112250
Human Monoclonal Uroplakin 3A Primary Antibody for IHC (p) - ABIN1687148
Knez, Barrow, Lucia, Wilson, La Rosa: Clear cell urothelial carcinoma of the urinary bladder: a case report and review of the literature. in Journal of medical case reports 2014
High expression level of preoperative serum Uroplakin III is associated with biologically aggressive bladder cancer.
High Uroplakin III expression is associated with bladder urothelial carcinoma from malignancy metastatic to the urinary bladder.
a strong association between UPIII and in the group with tumor recurrence
Loss of p63 (show RPE65 Antibodies) expression is a prerequisite for uroplakin III expression in urothelial bladder cancer.
Our results indicate that de novo mutations in UPIIIA can be involved in defective early kidney development, but probably constitute only a rare cause of human renal hypodysplasia in a minor subset of individuals [UPIIIA].
uroplakin III and III-delta4 genes were significantly up-regulated only in patients with nonulcerative interstitial cystitis
Uroplakin III mRNA is up-regulated to a greater extent in vesicoureteral reflux than in control exfoliated urinary cells.
Uroplakin III plays a pivotal role in Eshcerichia coli UTI (show AMBP Antibodies) pathogenesis.
studies suggest that bacteria-induced UPIIIa signaling is a critical mediator of bladder responses to insult by uropathogenic E. coli
A UPK3A peptide can induce a peptide-specific CD4 (show CD4 Antibodies)+ T cell autoimmunity that mediates painful bladder dysfunction in mice.
The despites a lower level of expression, UPIIIa maintain its plaque association in urothelial preneoplastic lesions.
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.
, uroplakin 3
, uroplakin IIIA
, uroplakin III
, proplakin IIIa