Uroporphyrinogen III Synthase (UROS) ELISA Kits

The protein encoded by UROS catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Additionally we are shipping Uroporphyrinogen III Synthase Antibodies (26) and Uroporphyrinogen III Synthase Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
UROS 7390 P10746
Anti-Mouse UROS UROS 22276 P51163
Anti-Rat UROS UROS 309070  
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Top Uroporphyrinogen III Synthase ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.114 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days

More ELISA Kits for Uroporphyrinogen III Synthase Interaction Partners

Cow (Bovine) Uroporphyrinogen III Synthase (UROS) interaction partners

  1. Study substantiated that insufficient activity of UROS is the cause of CEP in the family studied here. and provided strong evidence for LD between markers within the region and the phenotype.

Human Uroporphyrinogen III Synthase (UROS) interaction partners

  1. we show evidence that abnormal protein homeostasis is a prevalent mechanism responsible for UROS deficiency and that modulators of UROS proteolysis such as proteasome inhibitors or chemical chaperones may represent an attractive therapeutic option to reduce porphyrin accumulation and prevent skin photosensitivity in Congenital erythropoietic porphyria (CEP)patients when the genotype includes a missense variant.

  2. REVIEW: Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase and molecular basis of congenital erythropoietic porphyria

  3. Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

  4. Data show that branchpoint sequence (BPS)mutation reduced the wild-type transcript and UROS enzyme activity in CEP lymphoblasts to approximately 10% and 15% of normal, respectively.

  5. two novel misense mutations in the UROS gene.

  6. NMR analyses of URO-synthase titrated with competitive inhibitors N(D)-methyl-1-formylbilane or URO'gen III, revealed resonance perturbations of specific residues lining the cleft between 2 major domains of URO synthase that mapped enzyme's active site.

  7. The decrease in the expression of ubiquitous HMBS (show HMBS ELISA Kits) and UROS mRNAs under hypoxia is associated with accumulation of hypoxia-inducible factor 1alpha protein.

  8. UROS mutations related to erythropoietic porphyria identify a key helix for protein stability.

Mouse (Murine) Uroporphyrinogen III Synthase (UROS) interaction partners

  1. Data show that in adult UROS C73R mice, spleen and liver weights were 8.2- and 1.5-fold increased, respectively.

Arabidopsis thaliana Uroporphyrinogen III Synthase (UROS) interaction partners

  1. Data show that AtDuf3 genes were expressed in roots, leaves, shoot apical meristems, anthers and pollen grains. They may form homodimers or homopolymers, but did not interact with other members of the same family.

Uroporphyrinogen III Synthase (UROS) Antigen Profile

Antigen Summary

The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease).

Gene names and symbols associated with UROS

  • uroporphyrinogen III synthase (uros) antibody
  • uroporphyrinogen III synthase (UROS) antibody
  • uroporphyrinogen-III synthase (UroS) (AFUA_6G12800) antibody
  • uroporphyrinogen-iii synthase (UROS) antibody
  • uroporphyrinogen III synthase (UroS) antibody
  • uroporphyrinogen III synthase (Uros) antibody
  • Uroporphyrinogen-III synthase (HEMD) antibody
  • Afu6g12800 antibody
  • AI415298 antibody
  • ATDUF3 antibody
  • ATUROS antibody
  • DUF3 antibody
  • MGC85561 antibody
  • T9J22.21 antibody
  • T9J22_21 antibody
  • UROIIIS antibody
  • UROS antibody
  • Uros3 antibody
  • wu:fd13d11 antibody
  • zgc:110240 antibody

Protein level used designations for UROS

uroporphyrinogen-III synthase , uroporphyrinogen III synthase (congenital erythropoietic porphyria) , hydroxymethylbilane hydrolyase, cyclizing , uroporphyrinogen-III cosynthetase , uroporphyrinogen-iii synthase , uroporphyrinogen III synthase , hydroxymethylbilane hydrolyase , uroporphyrinogen-III cosynthase , URO-synthase , UROIIIS , hydroxymethylbilane hydrolyase (cyclizing) , urogen III synthase , uroporphyrinogen III co-synthase

404731 Danio rerio
426223 Gallus gallus
450813 Pan troglodytes
492116 Canis lupus familiaris
613425 Bos taurus
696043 Macaca mulatta
3508465 Aspergillus fumigatus Af293
5722253 Chlamydomonas reinhardtii
7452914 Thalassiosira pseudonana CCMP1335
100037610 Triticum aestivum
447178 Xenopus laevis
7390 Homo sapiens
22276 Mus musculus
309070 Rattus norvegicus
817195 Arabidopsis thaliana
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