Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by MAF is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Additionally we are shipping V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Kits (22) and V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) Proteins (8) and many more products for this protein.
Showing 10 out of 115 products:
Mouse (Murine) Polyclonal MAF Primary Antibody for ChIP, ICC - ABIN4285662
Nishimura, Kondo, Salameh, El Khattabi, Dodge, Bonner-Weir, Sharma: A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. in Developmental biology 2006
Show all 5 Pubmed References
Cow (Bovine) Polyclonal MAF Primary Antibody for IHC, IHC (p) - ABIN4285665
Hansen, Henderson, Lagos, Nikitenko, Coulter, Roberts, Gratrix, Plaisance, Renne, Bower, Kellam, Boshoff: KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. in Genes & development 2010
Show all 2 Pubmed References
Human Monoclonal MAF Primary Antibody for ELISA, WB - ABIN517678
Moreaux, Hose, Jourdan, Reme, Hundemer, Moos, Robert, Moine, De Vos, Goldschmidt, Klein: TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines. in Haematologica 2007
c-Maf is a critical transcription factor regulating T-cell specialization in mice, essential for generation of both RORgammat(+) Tregs and T follicular regulatory cells, but not for adipose-resident Tregs. c-Maf is induced in Tregs by IL-6 (show IL6 Antibodies) and TGF-beta (show TGFB1 Antibodies).
interplay between MATalpha1, c-Myc (show MYC Antibodies), and Maf proteins, and their deregulation during chronic cholestasis may facilitate cholangiocarcinoma oncogenesis
MafB (show MAFB Antibodies) and c-Maf have different expression patterns in macrophages, suggesting differences in function.
HERC4 (show HERC4 Antibodies) mediates c-Maf ubiquitination and delays growth of multiple myeloma.
Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin (show CRYAA Antibodies) both directly and indirectly via up-regulation of c-Maf.
Tec (show NR4A3 Antibodies) enhances c-Maf-dependent IL-4 (show IL4 Antibodies) promoter activity. This effect of Tec (show NR4A3 Antibodies) is counteracted by Ptpn22 (show PTPN22 Antibodies), which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf thereby attenuating its transcriptional activity.
endogenous small-Maf factors negatively regulate beta-cell function by competing for MafA (show MAFA Antibodies) binding, and thus, the inhibition of small-Maf activity can improve beta-cell function
The melanoma microenvironment contributes to skewing of CD8 (show CD8A Antibodies) T cell differentiation programs, in part by TGFbeta (show TGFB1 Antibodies)/IL-6 (show IL6 Antibodies)-mediated induction of Maf.
Sox5 (show SOX5 Antibodies) physically associates with c-Maf via the HMG (show SSRP1 Antibodies) domain of Sox5 (show SOX5 Antibodies) and DNA-binding domain of c-Maf, and Sox5 (show SOX5 Antibodies) together with c-Maf directly activates the promoter of RORgammat in CD4 (show CD4 Antibodies)(+) T cells.
KLF13 (show KLF13 Antibodies) directly binds to IL-4 (show IL4 Antibodies) promoter regions and synergizes with c-Maf to positively regulate IL-4 (show IL4 Antibodies) expression.
The interaction between c-Maf and RORgammat, and Blimp-1 (show PRDM1 Antibodies).
Polymorphisms rs9939609 (FTO (show FTO Antibodies) gene) and rs1424233 (MAF gene) were genotyped using allelic discrimination assays in a prospective multicenter cohort study; these polymorphisms did not show associations with birth weight, BMI and Ponderal Index at discharge, and weight gain, neither testing for a dominant, additive nor for a recessive model.
this study shows that genes associated with MAF-binding enhancers are suppressed in macrophages isolated from rheumatoid-arthritis patients, revealing a disease-associated signature of IFN-gamma (show IFNG Antibodies)-mediated repression
Our results argued that increased expression of sIL6R from myeloid cells and subsequent c-Maf induction were adverse events for counteracting tumor-specific Th1 (show TH1L Antibodies) generation. Overall, this work provides a mechanistic rationale for sIL6R targeting to improve the efficacy of T-cell-mediated cancer immunotherapy
These results define the role of MAF and GSK3 (show GSK3b Antibodies) in the resistance of t(14;16) multiple myeloma to proteasome inhibitors.
Epidermal differentiation gene regulatory networks are controlled by MAF and MAFB (show MAFB Antibodies).
Findings implicate the strong effects of ROS (show ROS1 Antibodies) on multiple stem cell functions with a central role for c-Maf in stem cell senescence.
Data suggest miR (show MLXIP Antibodies)-1290 as the new oncomiR involved in laryngeal squamous cell carcinoma pathogenesis probably through downregulation of its target genes MAF and ITPR2 (show ITPR2 Antibodies).
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
, V-maf musculoaponeurotic fibrosarcoma oncogene homolog
, c-Maf long form
, proto-oncogene c-maf
, transcription factor Maf
, Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene
, T lymphocyte c-maf long form
, c-maf proto-oncogene
, proto-oncogene c-Maf
, transcription factor Maf-2
, Proto-oncogene c-maf