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anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) Antibodies

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002. Additionally we are shipping V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Kits (10) and V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAFA 50928 O88713
MAFA 58975 Q64335
MAFA 389692 Q8NHW3
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Top anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of MAFA Antibody (C-term) (ABIN653391) in WiDr cell line lysates (35 µg/lane). MAFA (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MAFA Antibody (C-term) in WiDr cell line lysates (35ug/lane). MAFA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MAFA Antibody (C-term) in K562 cell line lysates (35ug/lane). This demonstrates the MAFA antibody detected the MAFA protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MAFA Antibody (Center) in mouse spleen tissue lysates (35ug/lane). MAFA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of MAFA Antibody (Center) (ABIN653392) in mouse spleen tissue lysates (35 µg/lane). MAFA (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

MAFA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Rat (Rattus)


Human ,
,
,
, , , , ,

Top referenced anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Antibodies

  1. Human Polyclonal MAFA Primary Antibody for EIA, WB - ABIN953282 : Garin, Martinez, de las Heras, Perez-Nanclares, Castano, Perez de Nanclares: Mutations in MAFA and IAPP are not a common cause of monogenic diabetes. in Diabetic medicine : a journal of the British Diabetic Association 2009 (PubMed)
    Show all 5 references for ABIN953282

  2. Human Polyclonal MAFA Primary Antibody for EIA, WB - ABIN953280 : Lecoin, Rocques, El-Yakoubi, Ben Achour, Larcher, Pouponnot, Eychène: MafA transcription factor identifies the early ret-expressing sensory neurons. in Developmental neurobiology 2010 (PubMed)
    Show all 4 references for ABIN953280

  3. Human Polyclonal MAFA Primary Antibody for EIA, WB - ABIN953281 : Martin, Flemming, Wang, Oeser, OBrien: Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression. in Journal of molecular endocrinology 2008 (PubMed)
    Show all 3 references for ABIN953281

  4. Human Polyclonal MAFA Primary Antibody for WB - ABIN653391 : Kondo, El Khattabi, Nishimura, Laybutt, Geraldes, Shah, King, Bonner-Weir, Weir, Sharma: p38 MAPK is a major regulator of MafA protein stability under oxidative stress. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

  5. Human Polyclonal MAFA Primary Antibody for WB - ABIN2783128 : Matsuoka, Kaneto, Stein, Miyatsuka, Kawamori, Henderson, Kojima, Matsuhisa, Hori, Yamasaki: MafA regulates expression of genes important to islet beta-cell function. in Molecular endocrinology (Baltimore, Md.) 2007 (PubMed)

More Antibodies against V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) Interaction Partners

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) interaction partners

  1. These findings demonstrate that regulation of monoamine levels by Mao (show MAO Antibodies) activity in beta cells is pivotal for physiological insulin (show INS Antibodies) secretion and that loss of MaoB (show MAOB Antibodies) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  2. is necessary for the maintenance of normal insulin (show INS Antibodies) levels even in embryos.

  3. endogenous small-Maf (show MAF Antibodies) factors negatively regulate beta-cell function by competing for MafA binding, and thus, the inhibition of small-Maf (show MAF Antibodies) activity can improve beta-cell function

  4. Data, including data from studies using transgenic/knockout mice, confirm the expression of Mafa and Mafb (show MAFB Antibodies) is specific to insulin (show INS Antibodies)-secreting cells of the pancreas.

  5. These results suggest that MafA regulates the postnatal proliferation of beta-cells via prolactin (show PRL Antibodies) signaling.

  6. This finding provides a rationale for the reciprocal expression of KLRG1 (show KLRG1 Antibodies) and CD103 (show ITGAE Antibodies) in different CD8 (show CD8A Antibodies)(+) T-cell subsets.

  7. results illustrate how consequential the reduction in Mafa activity is to islet beta-cell function under pathophysiological conditions.

  8. Cytotoxic KLRG1 (show KLRG1 Antibodies)-expressed CD8 (show CD8A Antibodies) effector cells and defective T regulatory cells cause murine autoimmune cholangitis.

  9. KLRG1 (show KLRG1 Antibodies)(+) iNKT cells coexpressing CD49d and granzyme A (show GZMA Antibodies) persisted for several months and displayed a potent secondary response to cognate antigen.

  10. Results not only clearly define why MafA is an essential transcriptional regulator of islet beta-cells, but also why cell maturation involves coordinated actions with MafB (show MAFB Antibodies).

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) interaction partners

  1. These findings demonstrate that regulation of monoamine levels by Mao (show MAO Antibodies) activity in beta cells is pivotal for physiological insulin (show INS Antibodies) secretion and that loss of MaoB (show MAOB Antibodies) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  2. MAFA (show KLRG1 Antibodies), MAFB (show MAFB Antibodies), NKX6.1 (show NKX6-1 Antibodies), and PDX1 (show PDX1 Antibodies) activity provides a gauge of islet beta cell function, with loss of MAFA (show KLRG1 Antibodies) (and/or MAFB (show MAFB Antibodies)) representing an early indicator of beta cell inactivity

  3. Loss of MAFA (show KLRG1 Antibodies) expression is associated with insulinoma (show RPS15 Antibodies).

  4. MAFA (show KLRG1 Antibodies) nuclear expression in pancreatic alpha and beta cells, and the percentage of alpha cells expressing PAX4 (show PAX4 Antibodies) are altered in patients with type 2 diabetes.

  5. under oxidative and nonoxidative conditions p38 MAPK (show MAPK14 Antibodies) directly binds to MafA (show KLRG1 Antibodies) and triggers MafA (show KLRG1 Antibodies) degradation via ubiquitin proteasomal pathway.

  6. Beta cell nuclear MafA (show KLRG1 Antibodies) is markedly decreased in humans with type 2 diabetes, which may contribute to impaired beta cell dysfunction.

  7. Combined transfection of the three transcriptional factors, PDX-1 (show PDX1 Antibodies), NeuroD1 (show NEUROD1 Antibodies), and MafA (show KLRG1 Antibodies), causes differentiation of bone marrow mesenchymal stem cells into insulin (show INS Antibodies)-producing cells

  8. Data suggest that MafA (show KLRG1 Antibodies) plays a novel role in the reprogramming of stem cells into pancreatic beta-progenitors, promotes the islet-like characteristics of PDMSCs, as well as functionally regulation of blood glucose levels in transplanted grafts.

  9. ATF2 (show ATF2 Antibodies) interacts with beta-cell-enriched transcription factors, MafA (show KLRG1 Antibodies), Pdx1 (show PDX1 Antibodies), and beta2, and activates insulin (show INS Antibodies) gene transcription.

  10. MafA (show KLRG1 Antibodies) transcription is upregulated in beta-cells acutely cultured in high glucose similar to what may occur in vivo under normoglycemic conditions.

V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) Antigen Profile

Protein Summary

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS\; MIM 176730) (Olbrot et al., 2002

Gene names and symbols associated with MAFA

  • killer cell lectin-like receptor subfamily G, member 1 (Klrg1) antibody
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (mafa) antibody
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene A (Mafa) antibody
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) antibody
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) (Mafa) antibody
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) antibody
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) (mafa) antibody
  • 2F1-Ag antibody
  • hMafA antibody
  • L-MAF antibody
  • MAFA antibody
  • MAFA-L antibody
  • mafl antibody
  • RGD1562627 antibody
  • RIPE3b1 antibody
  • SMaf1 antibody

Protein level used designations for MAFA

killer cell lectin-like receptor subfamily G member 1 , mast cell function-associated antigen 2F1 , mast cell function-associated antigen , v-maf musculoaponeurotic fibrosarcoma oncogene homolog A , Transcription factor MafA , leucine zipper transcription factor , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A , pancreatic beta-cell-specific transcriptional activator , transcription factor MafA , transcription factor RIPE3b1 , Mafa homolog , V-maf musculoaponeurotic fibrosarcoma oncogene homolog A , bZIP transcription factor L-Maf , lens-specific Maf , somite Maf1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein L

GENE ID SPECIES
50928 Mus musculus
58975 Rattus norvegicus
613050 Xenopus (Silurana) tropicalis
366949 Rattus norvegicus
389692 Homo sapiens
378435 Mus musculus
395881 Gallus gallus
100000492 Danio rerio
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