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V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog Proteins (MOS)

MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1\; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009].. Additionally we are shipping MOS Antibodies (100) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MOS 24559  
MOS 17451  
MOS 4342 P00540
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Top MOS Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast REACT_Andean condor His tag   1 mg Log in to see 56 to 66 Days
$2,486.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,918.67
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,937.00
Details
Yeast REACT_Green monkey His tag   1 mg Log in to see 56 to 66 Days
$2,938.83
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,948.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

MOS Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human , ,
,

More Proteins for V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog (MOS) Interaction Partners

Zebrafish V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog (MOS) interaction partners

  1. employed genetic linkage analysis and physical mapping to place the mosm188 mutation on chromosome 6 in the vicinity of the foxd3 (show FOXD3 Proteins) gene

Mouse (Murine) V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog (MOS) interaction partners

  1. In Xenopus oocytes, the N-terminal Pro of murine & Xenopus c-MOS is dispensable for degradation if Ser-2 of c-MOS is replaced by a small non-phosphorylatable residue. The N-terminal Pro residue is not a recognition determinant for a ubiquitin ligase.

  2. Mos protein is unstable in early mouse embryos

  3. This suggests that c-mos might play important roles in spermatogenesis

  4. Cdc2 (show CDK1 Proteins) and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition

Xenopus laevis V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog (MOS) interaction partners

  1. Mos is responsible for the mitotic activation of the p42 MAPK (show MAPK1 Proteins) pathway in Xenopus egg extracts.

  2. Results suggest that the specific synthesis of either B-type cyclins or c-Mos, induced by progesterone, is required to induce meiotic maturation and Cdc2 activation.

  3. Thus, Mos and Erp1 (show FBXO43 Proteins) collaboratively establish and maintain metaphase II arrest in Xenopus eggs

  4. results clarify the direct link of the classical Mos-MAPK pathw (show MAPK1 Proteins)ay to Erp1 in meiotic arrest of ve (show MAPK1 Proteins)rtebrate oocytes

Human V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog (MOS) interaction partners

  1. approach identified 18 kinase and kinase-related genes whose overexpression can substitute for EGFR (show EGFR Proteins) in EGFR (show EGFR Proteins)-dependent PC9 (show PCSK9 Proteins) cells, and these genes include seven of nine Src (show SRC Proteins) family kinase genes, FGFR1 (show FGFR1 Proteins), FGFR2 (show FGFR2 Proteins), ITK (show ITK Proteins), NTRK1 (show NTRK1 Proteins), NTRK2 (show NTRK2 Proteins), MOS, MST1R (show MST1R Proteins), and RAF1 (show RAF1 Proteins).

  2. High methylation level in MOS is associated with intestinal metaplasia.

  3. among the candidate genes, DNA methylation (show HELLS Proteins) of MOS may reflect the duration of H. pylori exposure and may be a marker for the development of gastric cancer.

  4. In the absence of p53 (show TP53 Proteins), Mos knockdown prevents multipolar mitoses and exerts genome-stabilizing effects.

  5. multiple meiotic genes are aberrantly activated during mitotic catastrophe in p53 (show TP53 Proteins) mutated lymphoma cells after irradiation; the coordinated expression of MOS and REC8 (show REC8 Proteins) regulate the extent of arrested mitoses and polyploidy

  6. Mos 3' UTR regulatory differences underlie species-specific temporal patterns of Mos mRNA cytoplasmic polyadenylation and translational recruitment during oocyte maturation.

  7. Cdc2 (show CDK1 Proteins) and Mos regulate Emi2 (show FBXO43 Proteins) stability to promote the meiosis I-meiosis II transition

  8. These results clarify the direct link of the classical Mos-MAPK (show MAPK1 Proteins) (mitogen-activated protein kinase (show MAPK1 Proteins)) pathway to Erp1 (show FBXO43 Proteins) in meiotic arrest of vertebrate oocytes.

  9. the Mos/MAPK (show MAPK1 Proteins) pathway is not essential for initiating goldfish oocyte maturation despite its general function as a cytostatic factor (CSF (show CSF2 Proteins)).

Pig (Porcine) V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog (MOS) interaction partners

  1. the length of the MOS 3'-UTR tightly controls the level of translation during oocyte maturation. two U-rich (U5A) elements and the hexanucleotide signal (AAUAAA) are required for translation.

MOS Protein Profile

Protein Summary

MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1\; MIM 176872) (Prasad et al., 2008

Gene names and symbols associated with MOS

  • v-mos Moloney murine sarcoma viral oncogene homolog (MOS)
  • v-mos Moloney murine sarcoma viral oncogene homolog (mos)
  • v-mos Moloney murine sarcoma viral oncogene homolog (LOC100229612)
  • v-mos Moloney murine sarcoma viral oncogene homolog (LOC100356433)
  • Moloney sarcoma oncogene (Mos)
  • c-mos protein
  • MOS protein
  • mosxe protein
  • MSV protein
  • p39 protein
  • p39-mos protein

Protein level used designations for MOS

v-mos Moloney murine sarcoma viral oncogene homolog , proto-oncogene serine/threonine-protein kinase mos , Moloney murine sarcoma viral (v-mos) oncogene homolog , c-mos , oocyte maturation factor mos , proto-oncogene c-Mos , v-mos moloney murine sarcoma viral oncogene homolog , c-mos proto-oncogene , c-mos oncogene , pp39-mos , serine/threonine-protein kinase mos , oncogene MOS, Moloney murine sarcoma virus , oocyte maturation factor Mos

GENE ID SPECIES
472772 Pan troglodytes
698921 Macaca mulatta
795517 Danio rerio
100135289 Xenopus (Silurana) tropicalis
100229612 Taeniopygia guttata
100356433 Oryctolagus cuniculus
24559 Rattus norvegicus
17451 Mus musculus
397924 Xenopus laevis
4342 Homo sapiens
486959 Canis lupus familiaris
100127484 Sus scrofa
428537 Gallus gallus
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