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V-Ral Simian Leukemia Viral Oncogene Homolog B Proteins (LOC100346449)

LOC100346449 encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins.

list all proteins Gene Name GeneID UniProt
LOC100346449 5899 P11234
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Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Human Un-conjugated 2 μg Log in to see 6 Days
$168.54
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More Proteins for V-Ral Simian Leukemia Viral Oncogene Homolog B (LOC100346449) Interaction Partners

Human V-Ral Simian Leukemia Viral Oncogene Homolog B (LOC100346449) interaction partners

  1. These findings suggest that RalB (show Ralb Proteins) might be one of the targets for facilitating the invasive phenotype of malignant gliomas induced by GGTase-I.

  2. striking isoform-specific consequences of distinct CAAX-signaled posttranslational modifications that contribute to the divergent subcellular localization and activity of RalA (show rala Proteins) and RalB (show Ralb Proteins).

  3. expression of K-Ras (show HRAS Proteins) and RalB (show Ralb Proteins) and possibly RalA (show rala Proteins) proteins is critical for maintaining low levels of p53 (show TP53 Proteins), and down-regulation of these GTPases reactivates p53 (show TP53 Proteins) by significantly enhancing its stability, contributing to suppression of malignant transformation

  4. High RALB (show Ralb Proteins) mRNA expression is associated with non-small-cell lung cancer growth and progression.

  5. Integrin alpha(v (show ITGAV Proteins))beta expression and the resulting KRAS-RalB (show Ralb Proteins)-NF-kappaB (show NFKB1 Proteins) pathway were both necessary and sufficient for tumour initiation, anchorage independence, self-renewal and erlotinib resistance.

  6. nutrient starvation induces RALB (show Ralb Proteins) deubiquitylation by accumulation and relocalization of the deubiquitylase USP33 (show USP33 Proteins) to RALB (show Ralb Proteins)-positive vesicles

  7. RalA (show rala Proteins) and RalB (show Ralb Proteins) exhibit both distinct and redundant roles in tumorigenesis (Review).

  8. The study found upregulated RalA (show rala Proteins) and RalB (show Ralb Proteins) activation in colorectal cancer tumor cell lines and tumors.

  9. the existence of an ubiquitination/de-ubiquitination cycle superimposed on the GDP/GTP (show AK3 Proteins) cycle of RalA (show rala Proteins), involved in the regulation of RalA (show rala Proteins) activity as well as in membrane raft trafficking.

  10. RalA (show rala Proteins) and RalB (show Ralb Proteins) differentially regulate development of epithelial tight junctions.

V-Ral Simian Leukemia Viral Oncogene Homolog B (LOC100346449) Protein Profile

Protein Summary

This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors.

Gene names and symbols associated with LOC100346449

  • v-ral simian leukemia viral oncogene homolog B (RALB)

Protein level used designations for LOC100346449

RAS-like protein B , ras related GTP binding protein , ras-related protein Ral-B , v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)

GENE ID SPECIES
5899 Homo sapiens
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