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V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (Avian) Proteins (RELA)

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes.

list all proteins Gene Name GeneID UniProt
RELA 5970 Q04206
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Top RELA Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (Avian) (RELA) (AA 1-210), (partial) protein (GST tag) 1 mg Log in to see 56 to 66 Days
$1,842.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$285.71
Details

RELA Proteins by Origin and Source

Origin Expressed in Conjugate
Human

More Proteins for V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (Avian) (RELA) Interaction Partners

Human V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (Avian) (RELA) interaction partners

  1. Obstructive sleep apnea-hypopnea syndrome pathogenesis was associated with changes in NF-kappaB (show NFKB1 Proteins), HIF-1alpha (show HIF1A Proteins), and SPD (show HOXD13 Proteins) protein expression level

  2. Data indicate that an evident reduction in p-NF-kappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins) expression was observed in the fibroblasts in which telomerase reverse transcriptase (show TERT Proteins) (hTERT) expression was silenced.

  3. As examined by the NF-kappaB (show NFKB1 Proteins) luciferase reporter assay, we found that baicalein suppressed TNF-a (show TNF Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation in a dose-dependent manner. It also inhibited TNF-a (show TNF Proteins)-induced nuclear translocation of p65 (show GORASP1 Proteins) through inhibition of phosphorylation and degradation of IkBa (show NFKBIA Proteins).

  4. Our results showed that melatonin treatment inhibited NFkappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins) activation. Moreover, melatonin treatment activated the mitogenactivated protein kinase (show CDK7 Proteins) pathways (cjun (show JUN Proteins) Nterminal kinase and extracellularregulated kinase 1/2), which increased Bax (show BAX Proteins) protein expression and caspase3 cleavage and decreased Bcl2 (show BCL2 Proteins) protein expression

  5. By screening the signalling pathways, we observed an obvious upregulation of phosphorylated NF-kappaB (show NFKB1 Proteins) in A549 and H520 cells after silencing of FOXP3 (show FOXP3 Proteins). Our results suggest that Foxp3 (show FOXP3 Proteins) suppressed NSCLC cell metastasis, at least partially, via NF-kappaB (show NFKB1 Proteins) signaling.

  6. Indoxyl sulfate upregulates NF-kappaB (show NFKB1 Proteins), which leads to increase CYP24 (show CYP24A1 Proteins) expression and ROS (show ROS1 Proteins) production in renal tubular epithelial cells.

  7. Tim-3 (show HAVCR2 Proteins) facilitates osteosarcoma proliferation and metastasis through the NF-kappaB (show NFKB1 Proteins) pathway and epithelial-mesenchymal transition.

  8. W346 effectively inhibited tumor necrosis factor (TNF-a (show TNF Proteins))-induced NF-kappaB (show NFKB1 Proteins) activation by suppressing IKK (show CHUK Proteins) phosphorylation, inhibiting IkB (show NFKBIB Proteins)-a degradation, and restraining the accumulation of NF-kappaB (show NFKB1 Proteins) subunit p65 (show GORASP1 Proteins) nuclear translocation. W346 also affected NF-kappaB (show NFKB1 Proteins)-regulated downstream products involved in cycle arrest and apoptosis.

  9. treating cells with SZC014 resulted in a decrease in phosphorylation of IkBa (show NFKBIA Proteins) and NF-kappaB (show NFKB1 Proteins)/p65 (show GORASP1 Proteins) and NF-kappaB (show NFKB1 Proteins)/p65 (show GORASP1 Proteins) nuclear translocation. The cytotoxic activities of seven OA derivatives were generally stronger than that of OA, among which, SZC014 possessed the most potent anticancer activity in SGC7901 cells and would be a promising chemotherapic agent for the treatment of gastric cancer.

  10. N-Myc (show MYCN Proteins)-interacting protein (NMI (show MYO1C Proteins)) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-kappaB (show NFKB1 Proteins)/p65 (show GORASP1 Proteins) in histone deacetylase (show HDAC1 Proteins)-dependent manner.

Cow (Bovine) V-Rel Reticuloendotheliosis Viral Oncogene Homolog A (Avian) (RELA) interaction partners

  1. Hepatic SREBP-1c (show SREBF1 Proteins)-mediated lipid synthesis and the NF-kappaB (show NFKB1 Proteins) inflammatory pathway were both overinduced in cows with fatty liver.

  2. Cytopathic bovine viral diarrhea virus strain induces immune marker production in bovine cells through the NF-kappaB (show NFKB1 Proteins) signaling pathway.

  3. The role of NF-kappaB (show NFKB1 Proteins) and C/EBP (show CEBPA Proteins) factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated.

  4. Altering the extracellular matrix to promote p38 (show MAPK14 Proteins) activation in cells on fibronectin (show FN1 Proteins) suppresses NF-kappaB (show NFKB1 Proteins) activation, suggesting a novel therapeutic strategy for treating

  5. full length coding sequence of the cattle transcription factor p65 (show NFkBP65 Proteins) was isolated and cloned

  6. the pathogen causing subclinical mastitis impairs NF-kappaB (show NFKB1 Proteins) activation in MEC (show CCL28 Proteins) thereby severely weakening the immune response,induction of IL-8 (show IL8 Proteins) and TNFalpha (show TNF Proteins), in the udder

  7. These results confirm that VEGI (show TNFSF15 Proteins) utilizes NF-kappaB (show NFKB1 Proteins) as a pro-survival role factor in endothelial cells.

RELA Protein Profile

Protein Summary

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RELA

  • v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA)
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian) (RELA)
  • NFKB3 protein
  • p65 protein

Protein level used designations for RELA

NF-kappa-B p65delta3 , nuclear factor NF-kappa-B p65 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 , transcription factor p65 , v-rel reticuloendotheliosis viral oncogene homolog A , NF-kB p65 subunit , NF-kappaB transcription factor p65 subunit , v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65

GENE ID SPECIES
5970 Homo sapiens
396027 Gallus gallus
508233 Bos taurus
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