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anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Antibodies

VTCN1 encodes a protein belonging to the B7 costimulatory protein family. Additionally we are shipping VTCN1 Proteins (26) and VTCN1 Kits (22) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VTCN1 242122 Q7TSP5
VTCN1 79679 Q7Z7D3
VTCN1 295322 Q501W4
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Top anti-VTCN1 Antibodies at antibodies-online.com

Showing 10 out of 167 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN334524 (0.3µg/ml) staining of Human Spleen lysate (35µg protein in... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse FITC FACS 0.1 mg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of VTCN1 Antibody (Center) in T47D cell line lys... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, IHC (fro), IHC (p) 0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human thyroid carcinoma labeled A... Formalin-fixed and paraffin embedded human gastric carcinoma labeled A... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB B7-H4 staining in human lung cancer. Paraffin-embedded human lung canc... 0.1 mg Log in to see 2 to 6 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Mouse PE FACS 100 Tests Log in to see 6 to 8 Days
$434.50
Details
Human Mouse PE FACS 100 Tests Log in to see 8 to 10 Days
$522.50
Details
Mouse Rat Un-conjugated FACS Staining of non -transfected (left) and mouse B7 -H4 -GFP transfected ... 50 μg Log in to see 5 to 6 Days
$121.08
Details

VTCN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
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Human , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-VTCN1 Antibodies

  1. Human Polyclonal VTCN1 Primary Antibody for IHC, ELISA - ABIN1584048 : Basta, Galazka, Mach, Jozwicki, Walentowicz, Wicherek: The immunohistochemical analysis of RCAS1, HLA-G, and B7H4-positive macrophages in partial and complete hydatidiform mole in both applied therapeutic surgery and surgery followed by chemotherapy. in American journal of reproductive immunology (New York, N.Y. : 1989) 2011 (PubMed)
    Show all 4 references for ABIN1584048

  2. Human Polyclonal VTCN1 Primary Antibody for EIA, WB - ABIN955537 : Xue, Luan, Gu, Wu, Zhang, Yu, Zhu, Wang, Dong, Geng, Zhang: The negative co-signaling molecule b7-h4 is expressed by human bone marrow-derived mesenchymal stem cells and mediates its T-cell modulatory activity. in Stem cells and development 2010 (PubMed)
    Show all 4 references for ABIN955537

  3. Mouse (Murine) Monoclonal VTCN1 Primary Antibody for FACS - ABIN281035 : Prasad, Richards, Mai, Dong: B7S1, a novel B7 family member that negatively regulates T cell activation. in Immunity 2003 (PubMed)

  4. Human Polyclonal VTCN1 Primary Antibody for ELISA, WB - ABIN334524 : Krambeck, Thompson, Dong, Lohse, Park, Kuntz, Leibovich, Blute, Cheville, Kwon: B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  5. Human Polyclonal VTCN1 Primary Antibody for IF (p), IHC (p) - ABIN671736 : Maskey, Li, Hu, Xu, Peng, Yu, Cao, Chen, Li, Yang: Impact of neoadjuvant chemotherapy on lymphocytes and co-inhibitory B7-H4 molecule in gastric cancer: low B7-H4 expression associates with favorable prognosis. in Tumour biology 2014 (PubMed)

More Antibodies against VTCN1 Interaction Partners

Mouse (Murine) V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) interaction partners

  1. Results highlight an importance of VTCN1 stabilization on cell surfaces for the restora (show APCS Antibodies)tion of altered balance of immune control during T1D.

  2. Ablation of B7-H3 (show CD276 Antibodies) but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

  3. B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity.

  4. that B7x can modulate kidney damage in autoimmune diseases including lupus nephritis and anti-glomerular basement membrane disease

  5. B7-H4 can inhibit both antitumor T cells and protumor myeloid-derived suppressor cells (

  6. The endogenous expression of B7-H4 in donor beta cells from transgenic mice prolongs islet allograft survival, confirming the negative role of B7-H4 in regulating alloreactive T-cell responses.

  7. Local overexpression of B7x on pancreatic beta cells is sufficient to abolish CD8 (show CD8A Antibodies) T cell-induced diabetes.

  8. B7-H4 expression may influence the outcome of T-cell tumor cell interactions. Tumor-associated macrophage induced membrane-bound B7-H4 on lung cancer cell represents a novel mechanism by which lung cancer cells evade immune recognition and destruction.

  9. Overexpression of B7-H4 was shown in tumor infiltrated dendritic cells.

  10. Tissue-specific expression of B7x protects from CD4 (show CD4 Antibodies) T cell-mediated autoimmunity.

Human V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) interaction partners

  1. Data show that disrupted control of costimulation, evidenced by VTCN1 loss in both APCs (show APCS Antibodies) and pancreatic islets, ultimately results in altered balance of control of immune responses.

  2. Studied VTCN1 gene polymorphisms in susceptibility to Breast Cancer.

  3. Data indicate that the diagnostic efficiency of V-set domain containing T cell activation inhibitor 1 (sB7-H4) combined carcinoembryonic antigen (CEA (show CEACAM5 Antibodies)) was superior to either sB7-H4 or CEA (show CEACAM5 Antibodies).

  4. In human amniotic fluid stem cells, the negative co-stimulatory molecule B7H4 regulates low immunogenicity, which can provide a modest inflammatory reaction microenvironment for wound repair.

  5. Low expression of VTCN1 inhibits the viability and metastasis of ovarian carcinoma.

  6. B7-H4 expressed is elevated in colorectal cancer tissues than in the adjacent normal tissues. B7-H4 siRNA effectively inhibited the proliferation at 24 h and 48 h, arrested cell cycle at G0/G1, and suppressed cell invasion and migration.

  7. our data suggest that the evaluation of B7-H4 expression in tissues and blood is a useful tool for predicting the progression of osteosarcoma and prognosis

  8. B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity.

  9. B7-H4 levels in hepatocellular carcinoma patients were significantly higher than that in healthy controls. High B7-H4 levels were correlated with tumor size, tumor invasion, tumor differentiation and tumor-node metastasis stage.

  10. B7-H4 is overexpressed in human cervical cancers, and it is associated with low numbers of infiltrating CD8 (show CD8A Antibodies)+T-lymphocytes and correspondingly low interferon-gamma (show IFNG Antibodies) production.

VTCN1 Antigen Profile

Protein Summary

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with VTCN1

  • V-set domain containing T cell activation inhibitor 1 (vtcn1) antibody
  • V-set domain containing T cell activation inhibitor 1 (VTCN1) antibody
  • V-set domain containing T cell activation inhibitor 1 (Vtcn1) antibody
  • B7-H4 antibody
  • B7h.5 antibody
  • B7H4 antibody
  • B7S1 antibody
  • B7X antibody
  • BC032925 antibody
  • PRO1291 antibody
  • RGD1311204 antibody
  • VCTN1 antibody

Protein level used designations for VTCN1

V-set domain-containing T-cell activation inhibitor 1 , V-set domain containing T cell activation inhibitor 1 , V-set domain containing T-cell activation inhibitor 1 , immune costimulatory protein B7-H4 , t cell costimulatory molecule B7x , B7 family member, H4 , B7 superfamily member 1 , T cell costimulatory molecule B7x , T-cell costimulatory molecule B7x

GENE ID SPECIES
379070 Xenopus laevis
418323 Gallus gallus
469433 Pan troglodytes
493551 Xenopus (Silurana) tropicalis
242122 Mus musculus
79679 Homo sapiens
295322 Rattus norvegicus
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