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anti-V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) Antibodies

VSIG4 encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. Additionally we are shipping VSIG4 Proteins (15) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VSIG4 11326 Q9Y279
VSIG4 278180  
VSIG4 312102  
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Top anti-VSIG4 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-VSIG4 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-VSIG4 AntibodyTitration: 1.0 µg/mL Positive Control: COLO205 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB VSIG4 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the VSIG4 antibody detected the VSIG4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat lung labeled with Anti- VSIG4 Polyclonal Antibody, Unconjugated  at 1:300 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 16 Days
$308.00
Details

VSIG4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine) , ,
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Rat (Rattus)


Top referenced anti-VSIG4 Antibodies

  1. Mouse (Murine) Polyclonal VSIG4 Primary Antibody for ELISA - ABIN2000517 : Helmy, Katschke, Gorgani, Kljavin, Elliott, Diehl, Scales, Ghilardi, van Lookeren Campagne: CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. in Cell 2006 (PubMed)
    Show all 6 references for ABIN2000517

  2. Human Polyclonal VSIG4 Primary Antibody for ELISA - ABIN1999583 : Wiesmann, Katschke, Yin, Helmy, Steffek, Fairbrother, McCallum, Embuscado, DeForge, Hass, van Lookeren Campagne: Structure of C3b in complex with CRIg gives insights into regulation of complement activation. in Nature 2006 (PubMed)
    Show all 6 references for ABIN1999583

  3. Cow (Bovine) Polyclonal VSIG4 Primary Antibody for WB - ABIN2776895 : Otsuki, Ota, Nishikawa, Hayashi, Suzuki, Yamamoto, Wakamatsu, Kimura, Sakamoto, Hatano, Kawai, Ishii, Saito, Kojima, Sugiyama, Ono, Okano, Yoshikawa, Aotsuka, Sasaki, Hattori, Okumura, Nagai, Sugano et al.: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. ... in DNA research : an international journal for rapid publication of reports on genes and genomes 2005 (PubMed)

More Antibodies against VSIG4 Interaction Partners

Human V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) interaction partners

  1. Data indicate that rotein kinase calpha (show PRKACA Antibodies) (PKCalpha (show PKCa Antibodies)) plays a role in downregulating complement receptor Ig (CRIg coded by V-set and Ig domain-containing protein 4 VSIG4) expression.

  2. complement receptor of the immunoglobulin superfamily-L-factor H (show CFH Antibodies) protects glomerular mesangial cells from complement-mediated injury and proliferative lesions

  3. we identified VSIG4 as a potential diagnostic marker of severe preeclampsia. The determination of this gene may improve the prognostic assessment of severe preeclampsia.

  4. Data indicate that massive V-set and Ig domain-containing 4 VSIG4(+) cell infiltration throughout the non-small-cell lung cancer samples.

  5. we showed that a complement receptor of the Ig superfamily (CRIg, also known as Z39Ig), a receptor for complement fragments (C3b and iC3b), was expressed on a subset of intestinal macrophages in murine and human large intestine

  6. These results suggest that T cells can opposite T cell hyporesponsiveness through dampening Z39Ig inhibitory signals from macrophages and thus maintain their anti-viral function in chronic hepatitis B.

  7. Results report the identification and characterization of a Complement Receptor of the Immunoglobulin superfamily, CRIg, that binds complement fragments C3b and iC3b.

  8. These data indicate that the macrophage Z39Ig is involved in the pathogenesis of inflammatory diseases through chemokine (show CCL1 Antibodies) induction, which will promote the migration of inflammatory cells into the lesion area, and MMP-9 (show MMP9 Antibodies) induction.

  9. The specific expression of VSIG4 on resting macrophages suggests that VSIG4 may be important for the maintenance of T cell unresponsiveness in healthy tissues.

  10. CRIg is not only a phagocytic receptor, but also a potent inhibitor of the alternative pathway convertases

Mouse (Murine) V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) interaction partners

  1. The macrophage-expressed VSIG4 may act to alleviate renal tubulointerstitial injury via inhibition of T cell infiltration and secretion of inflammation related factors.

  2. complement receptor of the immunoglobulin superfamily-L-factor H (show CFH Antibodies) protects glomerular mesangial cells from complement-mediated injury and proliferative lesions

  3. CRIg signals induce anti-intracellular bacterial phagosome activity in a chloride intracellular channel 3 (show CLIC3 Antibodies)-dependent manner.

  4. CRIg plays an important role in regulating virus-induced Kupffer cell death and depletion of these cells from the liver sinusoidal lumen

  5. we showed that a complement receptor of the Ig superfamily (CRIg, also known as Z39Ig), a receptor for complement fragments (C3b and iC3b), was expressed on a subset of intestinal macrophages in murine and human large intestine

  6. The interstitial inflammatory cell infiltration and tubular lesion of VSIG4(-/-); urethral obstruction operation mice were increased, with the expression of TGF-beta1 (show TGFB1 Antibodies) increased and MMP-2 (show MMP2 Antibodies) reduced. VSIG4 may play a role in inhibiting interstitial fibrosis.

  7. Results report the identification and characterization of a Complement Receptor of the Immunoglobulin superfamily, CRIg, that binds complement fragments C3b and iC3b.

  8. The specific expression of VSIG4 on resting macrophages suggests that VSIG4 may be important for the maintenance of T cell unresponsiveness in healthy tissues.

  9. A soluble form of complement receptor of the immunoglobulin superfamily (CRIg) reversed inflammation and bone loss in two experimental models of arthritis by inhibiting the alternative pathway of complement in the joint.

  10. Antibody blocking or gene ablation of the newly identified complement receptor CRIg, but not complement receptor 3 (CR3 (show ITGAM Antibodies)), rescued DAF (show CD55 Antibodies)/Crry (show CR1L Antibodies)-deficient platelets from complement-dependent elimination.

VSIG4 Antigen Profile

Protein Summary

This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with VSIG4

  • V-set and immunoglobulin domain containing 4 (VSIG4) antibody
  • V-set and immunoglobulin domain containing 4 (Vsig4) antibody
  • A530061A11 antibody
  • BC025105 antibody
  • CRIg antibody
  • DKFZp468O0322 antibody
  • Z39IG antibody

Protein level used designations for VSIG4

V-set and immunoglobulin domain containing 4 , V-set and immunoglobulin domain-containing protein 4 , Ig superfamily protein , complement receptor of the immunoglobulin superfamily , protein Z39Ig

GENE ID SPECIES
465677 Pan troglodytes
100171405 Pongo abelii
11326 Homo sapiens
614262 Bos taurus
278180 Mus musculus
312102 Rattus norvegicus
491925 Canis lupus familiaris
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