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V-Ski Sarcoma Viral Oncogene Homolog (Avian) Proteins (SKI)

SKI encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. Additionally we are shipping SKI Antibodies (30) and SKI Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SKI 20481  
SKI 6497 P12755
Rat SKI SKI 313757  
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Top SKI Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details

SKI Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human

More Proteins for V-Ski Sarcoma Viral Oncogene Homolog (Avian) (SKI) Interaction Partners

Mouse (Murine) V-Ski Sarcoma Viral Oncogene Homolog (Avian) (SKI) interaction partners

  1. our results demonstrate that SKI is an important regulator of hematopoietic stem cell activity and its overexpression leads to myeloproliferative disease.

  2. Trnsgenic mice overexpressing chicken Ski (c-Ski) have marked decrease in adipose mass with skeletal muscle hypertrophy Results suggest Ski plays a major role in skeletal muscle metabolism and adipogenesis and hence influences risk of obesity and diabetes

  3. After Qingyi Huaji treatment, Ski expression was reduced and pancreatic tumor growth slowed down significantly.

  4. Satb2 (show SATB2 Proteins) recruits Ski to the Ctip2 locus, and Ski attracts histone deacetylases, thereby enabling the formation of a functional nucleosome remodeling and deacetylase repressor complex.

  5. Data on expression of Ski suggest that Ski is involved in follicular development, oogenesis, ovulation, and luteinization. During the estrous cycle, Ski expression was apparent at proestrus and estrus, faint at metestrus, highest at diestrus.

  6. The presented data support a new role for Ski in the mitotic process and in maintenance of genetic stability

  7. Ski regulates several genetic programs and signalling pathways that regulate skeletal muscle and adipose mass to influence body composition development, suggesting that Ski may have a role in risk for obesity and metabolic disease.

  8. Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice

  9. SnoN (show SKIL Proteins) and Ski proteins are up-regulated during liver regeneration

  10. c-Jun (show JUN Proteins) associates with the oncoprotein Ski and suppresses Smad2 (show SMAD2 Proteins) transcriptional activity

Human V-Ski Sarcoma Viral Oncogene Homolog (Avian) (SKI) interaction partners

  1. our findings suggest that Ski represses TGF-b-induced EMT (show ITK Proteins) and invasion by inhibiting SMAD (show SMAD1 Proteins)-dependent signaling in non-small cell lung cancer

  2. Ski regulates Hippo and TAZ (show TAZ Proteins) signaling to suppress breast cancer progression.

  3. Eight recurrent and three novel SKI mutations from eleven SGS (show FBN1 Proteins) patients were located in the R-SMAD (show SMAD1 Proteins) binding domain, except for one in the DHD domain.

  4. acetaldehyde up-regulates COL1A2 (show COL1A2 Proteins) by modulating the role of Ski and the expression of SMADs 3, 4, and 7.

  5. c-Ski is an important regulator in the activation of CAFs and may serve as a potential therapeutic target to block breast cancer progression.

  6. Ski expression is a novel negative feedback mechanism acting on retinoic acid signaling

  7. Overall, these studies demonstrate altered Ski protein (show SKIL Proteins) levels, degradation and localization in human papillomavirus16-transformed human keratinocytes and in cervical cancer.

  8. The 1p36.33-1p36.32 deletion encompassing SKI may represents a previous undescribed microdeletion disorder.

  9. Transgenic K562 cells have distinct gene expression profiles both in steady state and during terminal erythroid differentiation, with GATA1s expression characterised by lack of repression of MYB (show MYB Proteins), CCND2 (show CCND2 Proteins) and SKI.

  10. The study data provide limited support for the hypothesis that common SKI variants are susceptibility factors for non-syndromic cleft lip/palate.

SKI Protein Profile

Protein Summary

This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.

Gene names and symbols associated with SKI

  • v-ski sarcoma viral oncogene homolog (avian) (SKI)
  • SKI (C-SKI)
  • ski sarcoma viral oncogene homolog (avian) (Ski)
  • superkiller viralicidic activity 2-like (S. cerevisiae) (Skiv2l)
  • v-ski avian sarcoma viral oncogene homolog (ski-b)
  • v-ski avian sarcoma viral oncogene homolog (SKI)
  • v-ski avian sarcoma viral oncogene homolog (Ski)
  • v-ski sarcoma viral oncogene homolog (SKI)
  • 2310012I02Rik protein
  • 2610001A11Rik protein
  • 4930534J06Rik protein
  • AA062172 protein
  • AA589460 protein
  • AW214248 protein
  • BC004088 protein
  • C-SKI protein
  • Ddx13 protein
  • RGD1565591 protein
  • SGS protein
  • ski protein
  • Ski2w protein
  • SKV protein
  • xski protein

Protein level used designations for SKI

v-ski sarcoma viral oncogene homolog (avian) , avian sarcoma viral (v-ski) oncogene homolog natural resistance-associated macrophage protein 1 , v-ski avian sarcoma viral oncogene-like protein , proto-oncogene c-Ski , ski oncogene , C-ski , Sloan-Kettering viral oncogene homolog , superkiller viralicidic activity 2-like , Ski2 , v-ski sarcoma viral oncogene homolog , ski oncoprotein , ski sarcoma viral oncogene homolog

GENE ID SPECIES
489610 Canis lupus familiaris
506127 Bos taurus
100030133 Monodelphis domestica
100033833 Equus caballus
20481 Mus musculus
108077 Mus musculus
399309 Xenopus laevis
6497 Homo sapiens
313757 Rattus norvegicus
428181 Gallus gallus
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