V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) ELISA Kits

ERG encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. Additionally we are shipping V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Antibodies (115) and V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse ERG ERG 13876 P81270
Anti-Rat ERG ERG 170909  
Anti-Human ERG ERG 2078 P11308
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More ELISA Kits for V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Interaction Partners

Xenopus laevis V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. KLF2 (show KLF2 ELISA Kits) and ERG associate in a physical complex and the two proteins synergistically activate transcription of Flk1 (show KDR ELISA Kits).

Mouse (Murine) V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. loss of ERG and FLI1 (show FLI1 ELISA Kits) might contribute to the pathogenesis of vascular lung complications through the induction of inflammation.

  2. Combined, these data suggest a possible pathway linking GDF5 (show GDF5 ELISA Kits), ERG and downstream factors in the processes of chondrocyte differentiation during articular joint formation.

  3. Our study reveals that ERG has essential and cell autonomous roles in endothelial cell development and blood vessel maintenance.

  4. We show that the gene expression signature specifically attributable to trisomy of Erg in the murine model is strongly correlated with gene expression changes in human Down syndrome hematopoietic cells.

  5. Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

  6. ERG plays a critical role in coordinating the balance between self-renewal and differentiation of HSCs.

  7. ERG activates the transcriptional program regulated by YAP1 (show YAP1 ELISA Kits) of the Hippo signaling pathway and found that prostate-specific activation of either ERG or YAP1 (show YAP1 ELISA Kits) in mice induces similar transcriptional changes and results in age-related prostate tumors.

  8. ERG and APLNR (show APLNR ELISA Kits) are essential for endothelial homeostasis in venules in the lung and that perturbation in ERG-APLNR (show APLNR ELISA Kits) signaling is crucial for the development of pulmonary veno-occlusive disease.

  9. Regulation of Erg by TGF-beta (show TGFB1 ELISA Kits) was confirmed in these cells.

  10. Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

Human V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. ERG, FLI1 (show FLI1 ELISA Kits), TAL1 (show TAL1 ELISA Kits), and RUNX1 (show RUNX1 ELISA Kits) bind at all AML1 (show RUNX1 ELISA Kits)-ETO (show RUNX1T1 ELISA Kits)-occupied regulatory regions, including those of the AML1 (show RUNX1 ELISA Kits)-ETO (show RUNX1T1 ELISA Kits) gene itself, suggesting their involvement in regulating AML1 (show RUNX1 ELISA Kits)-ETO (show RUNX1T1 ELISA Kits) expression levels.

  2. four oncogenic ETS (show ETS1 ELISA Kits) (ERG, ETV1 (show ETV1 ELISA Kits), ETV4 (show ETV4 ELISA Kits), and ETV5), and no other ETS (show ETS1 ELISA Kits), interact with the Ewing's sarcoma breakpoint protein, EWS (show EWSR1 ELISA Kits).

  3. We demonstrate a role for inflammation-induced oxidative stress in the formation of DNA breaks leading to recurrent TMPRSS2 (show TMPRSS2 ELISA Kits)-ERG gene fusions. The transcriptional status and epigenetic features of the target genes influence this effect.

  4. ERG signaling in prostate cancer is driven through PRMT5 (show PRMT5 ELISA Kits)-dependent methylation of the androgen receptor (show AR ELISA Kits).

  5. NOTCH (show NOTCH1 ELISA Kits) pathway inhibition antagonizes the growth and invasion of transmembrane protease serine 2 (TMPRSS2 (show TMPRSS2 ELISA Kits))-transforming protein ERG (ERG) (T2E) -positive prostate cancer cells.

  6. findings have identified critical molecular mechanisms involving ERK (show EPHB2 ELISA Kits)-mediated ERG activation that could be exploited for therapeutic intervention in ERG-positive prostate cancers.

  7. Detection of Gene Rearrangements in Circulating Tumor Cells: Examples of ALK (show ALK ELISA Kits)-, ROS1 (show ROS1 ELISA Kits)-, RET (show RET ELISA Kits)-Rearrangements in Non-Small-Cell Lung Cancer and ERG-Rearrangements in Prostate Cancer.(

  8. The TMPRSS2 (show TMPRSS2 ELISA Kits)-ERG gene fusion is the most frequently observed genetic aberration in Prostate cancer.

  9. Loss of ERG is associated with prostate tumors.

  10. Data show that homogeneous ERG positivity is very rare in prostate cancer, especially in elderly patients. However, development of subpopulations with ERG fusions may be a much more frequent event in ERG negative cancer foci as previously believed.

Zebrafish V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. fli1 (show FLI1 ELISA Kits), and etsrp, demonstrated that erg (show KCNH2 ELISA Kits) and fli1 (show FLI1 ELISA Kits) act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin (show CDH5 ELISA Kits)

  2. A combination of gain-of-function and loss-of-function studies suggested a redundant yet specific role for erg (show KCNH2 ELISA Kits) in both angioblast specification/proliferation and early angiogenesis, and a synergistic interaction with the critical ETS (show ETS1 ELISA Kits) factor etsrp.

V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) Antigen Profile

Antigen Summary

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with ERG

  • ERG, ETS transcription factor (ERG) antibody
  • potassium voltage-gated channel, subfamily H (eag-related), member 2 (KCNH2) antibody
  • v-ets avian erythroblastosis virus E26 oncogene homolog S homeolog (erg.S) antibody
  • v-ets avian erythroblastosis virus E26 oncogene homolog (erg) antibody
  • ETS transcription factor (Erg) antibody
  • ERG, ETS transcription factor (Erg) antibody
  • v-ets avian erythroblastosis virus E26 oncogene homolog L homeolog (erg.L) antibody
  • D030036I24Rik antibody
  • erg antibody
  • erg-3 antibody
  • erg_A antibody
  • erg_E antibody
  • p55 antibody
  • zgc:103429 antibody

Protein level used designations for ERG

v-ets erythroblastosis virus E26 oncogene like , Ether-a-go-go-related gene potassium channel 1 , Potassium voltage-gated channel subfamily H member 2 , v-ets erythroblastosis virus E26 oncogene homolog (avian) , v-ets erythroblastosis virus E26 oncogene homolog , erg gene (erg_E) , vascular ETS factor , transcriptional regulator ERG , avian erythroblastosis virus E-26 (v-ets) oncogene related , TMPRSS2/ERG fusion , ets-related , transcriptional regulator ERG (transforming protein ERG) , v-ets avian erythroblastosis virus E26 oncogene related , transcriptional regulator Erg , erg1

GENE ID SPECIES
100223535 Taeniopygia guttata
397334 Sus scrofa
473995 Pan troglodytes
100604101 Nomascus leucogenys
378619 Xenopus laevis
100216056 Xenopus (Silurana) tropicalis
13876 Mus musculus
170909 Rattus norvegicus
2078 Homo sapiens
378618 Xenopus laevis
374146 Gallus gallus
535231 Bos taurus
494073 Danio rerio
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