V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins (ERG)

ERG encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. Additionally we are shipping V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Antibodies (114) and V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ERG 13876 P81270
ERG 170909  
ERG 2078 P11308
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Top V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins at antibodies-online.com

Showing 9 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Bioactivity measured with Activity Assay Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
Yeast Human His tag   50 μg Log in to see 8 to 11 Days
$341.00
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Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$3,349.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

ERG Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Rat (Rattus)
Human , , , ,
, , ,

Top referenced V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins

  1. Human ERG Protein expressed in HEK-293 Cells - ABIN2720464 : He, Schepmoes, Shi, Wu, Fillmore, Gao, Smith, Qian, Rodland, Liu, Camp, Rastogi, Tan, Yan, Mohamed, Huang, Banerjee, Kagan, Srivastava, McLeod, Srivastava, Petrovics, Dobi, Srinivasan: Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods. in Journal of translational medicine 2015 (PubMed)

More Proteins for V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) Interaction Partners

Xenopus laevis V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. KLF2 (show KLF2 Proteins) and ERG associate in a physical complex and the two proteins synergistically activate transcription of Flk1 (show KDR Proteins).

Mouse (Murine) V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. loss of ERG and FLI1 (show FLI1 Proteins) might contribute to the pathogenesis of vascular lung complications through the induction of inflammation.

  2. Combined, these data suggest a possible pathway linking GDF5 (show GDF5 Proteins), ERG and downstream factors in the processes of chondrocyte differentiation during articular joint formation.

  3. Our study reveals that ERG has essential and cell autonomous roles in endothelial cell development and blood vessel maintenance.

  4. We show that the gene expression signature specifically attributable to trisomy of Erg in the murine model is strongly correlated with gene expression changes in human Down syndrome hematopoietic cells.

  5. Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

  6. ERG plays a critical role in coordinating the balance between self-renewal and differentiation of HSCs.

  7. ERG activates the transcriptional program regulated by YAP1 (show YAP1 Proteins) of the Hippo signaling pathway and found that prostate-specific (show KLK3 Proteins) activation of either ERG or YAP1 (show YAP1 Proteins) in mice induces similar transcriptional changes and results in age-related prostate tumors.

  8. ERG and APLNR (show APLNR Proteins) are essential for endothelial homeostasis in venules in the lung and that perturbation in ERG-APLNR (show APLNR Proteins) signaling is crucial for the development of pulmonary veno-occlusive disease.

  9. Regulation of Erg by TGF-beta (show TGFB1 Proteins) was confirmed in these cells.

  10. Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

Human V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. ERG deletion is associated with acute lymphoblastic leukemia.

  2. Study provide evidence that PTEN deletion and TMPRSS2 (show TMPRSS2 Proteins)-ERG gene fusion were mutually exclusive in patients with prostate neoplasm. TMPRSS2 (show TMPRSS2 Proteins)-ERG gene fusion was rare compared to peripheral zone tumors and to PTEN inactivation in T1a (show PDPN Proteins) transition zone tumors.

  3. ERG rearrangement, but not PTEN loss, is present in a minority of potential neoplastic precursor lesions in the prostate.

  4. Patients with Prostate cancer had significantly higher levels of the prostate cancer-associated gene ERG in post-digital rectal examination urine extracellular vesicles. Continued analysis of urine EVs offers the potential discovery of novel biomarkers for pre-biopsy Prostate cancer detection.

  5. loss of ERG and FLI1 (show FLI1 Proteins) might contribute to the pathogenesis of vascular lung complications through the induction of inflammation.

  6. Neither the expression of aberrant proteins from internally deleted allele nor the reduced expression of wild type ERG seem to provide a plausible explanation of the specific biology of ERG -related leukemia subgroup.

  7. Our results suggest that the immune response may differ between ERG negative and ERG positive prostatic carcinomas

  8. identified five phosphorylated serines on endogenous ERG in T-ALL and AML (show RUNX1 Proteins) cells.

  9. miR (show MLXIP Proteins)-204 upregulates androgen receptor (AR (show AR Proteins) ) and downregulates TMPRSS2 (show TMPRSS2 Proteins)/ERG through direct regulation of their promoter methylation and set of transcription factors during AR cancer-related reprogramming.

  10. differential expression of TMPRSS2 (show TMPRSS2 Proteins):ERG in urine exosomes in prostate cancer and controls

Zebrafish V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. fli1 (show FLI1 Proteins), and etsrp (show ETV2 Proteins), demonstrated that erg (show KCNH2 Proteins) and fli1 (show FLI1 Proteins) act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin (show CDH5 Proteins)

  2. A combination of gain-of-function and loss-of-function studies suggested a redundant yet specific role for erg (show KCNH2 Proteins) in both angioblast specification/proliferation and early angiogenesis, and a synergistic interaction with the critical ETS (show ETS1 Proteins) factor etsrp (show ETV2 Proteins).

V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) Protein Profile

Protein Summary

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with ERG

  • v-ets erythroblastosis virus E26 oncogene like (LOC100223535)
  • potassium voltage-gated channel, subfamily H (eag-related), member 2 (KCNH2)
  • v-ets erythroblastosis virus E26 oncogene homolog (avian) (ERG)
  • v-ets erythroblastosis virus E26 oncogene homolog (erg-b)
  • v-ets erythroblastosis virus E26 oncogene homolog (erg)
  • avian erythroblastosis virus E-26 (v-ets) oncogene related (Erg)
  • v-ets avian erythroblastosis virus E26 oncogene (Erg)
  • v-ets avian erythroblastosis virus E26 oncogene homolog (ERG)
  • v-ets avian erythroblastosis virus E26 oncogene homolog (erg-a)
  • v-ets erythroblastosis virus E26 oncogene homolog (ERG)
  • v-ets erythroblastosis virus E26 oncogene like (avian) (erg)
  • D030036I24Rik protein
  • erg protein
  • erg-3 protein
  • erg_A protein
  • erg_E protein
  • p55 protein
  • zgc:103429 protein

Protein level used designations for ERG

v-ets erythroblastosis virus E26 oncogene like , Ether-a-go-go-related gene potassium channel 1 , Potassium voltage-gated channel subfamily H member 2 , v-ets erythroblastosis virus E26 oncogene homolog (avian) , v-ets erythroblastosis virus E26 oncogene homolog , erg gene (erg_E) , vascular ETS factor , transcriptional regulator ERG , avian erythroblastosis virus E-26 (v-ets) oncogene related , TMPRSS2/ERG fusion , ets-related , transcriptional regulator ERG (transforming protein ERG) , v-ets avian erythroblastosis virus E26 oncogene related , transcriptional regulator Erg , erg1

GENE ID SPECIES
100223535 Taeniopygia guttata
397334 Sus scrofa
473995 Pan troglodytes
100604101 Nomascus leucogenys
378619 Xenopus laevis
100216056 Xenopus (Silurana) tropicalis
13876 Mus musculus
170909 Rattus norvegicus
2078 Homo sapiens
378618 Xenopus laevis
374146 Gallus gallus
535231 Bos taurus
494073 Danio rerio
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