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V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins (ERG)

ERG encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. Additionally we are shipping V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Antibodies (98) and V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ERG 13876 P81270
ERG 170909  
ERG 2078 P11308
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Top V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins at antibodies-online.com

Showing 8 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
$7,759.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Human His tag   50 μg Log in to see 8 to 11 Days
$341.00
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HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
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Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,349.50
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

ERG Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Rat (Rattus)
Human , , , ,
, ,

Top referenced V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) Proteins

  1. Human ERG Protein expressed in Human - ABIN2720464 : He, Schepmoes, Shi, Wu, Fillmore, Gao, Smith, Qian, Rodland, Liu, Camp, Rastogi, Tan, Yan, Mohamed, Huang, Banerjee, Kagan, Srivastava, McLeod, Srivastava, Petrovics, Dobi, Srinivasan: Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods. in Journal of translational medicine 2015 (PubMed)

More Proteins for V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) Interaction Partners

Xenopus laevis V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. KLF2 (show KLF2 Proteins) and ERG associate in a physical complex and the two proteins synergistically activate transcription of Flk1 (show KDR Proteins).

Mouse (Murine) V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. Combined, these data suggest a possible pathway linking GDF5 (show GDF5 Proteins), ERG and downstream factors in the processes of chondrocyte differentiation during articular joint formation.

  2. Our study reveals that ERG has essential and cell autonomous roles in endothelial cell development and blood vessel maintenance.

  3. We show that the gene expression signature specifically attributable to trisomy of Erg in the murine model is strongly correlated with gene expression changes in human Down syndrome hematopoietic cells.

  4. Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

  5. ERG plays a critical role in coordinating the balance between self-renewal and differentiation of HSCs.

  6. ERG activates the transcriptional program regulated by YAP1 (show YAP1 Proteins) of the Hippo signaling pathway and found that prostate-specific (show KLK3 Proteins) activation of either ERG or YAP1 (show YAP1 Proteins) in mice induces similar transcriptional changes and results in age-related prostate tumors.

  7. ERG and APLNR (show APLNR Proteins) are essential for endothelial homeostasis in venules in the lung and that perturbation in ERG-APLNR (show APLNR Proteins) signaling is crucial for the development of pulmonary veno-occlusive disease.

  8. Regulation of Erg by TGF-beta (show TGFB1 Proteins) was confirmed in these cells.

  9. Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

  10. Expression of ERG and ETV1 correlated with higher AR transcriptional output in PTEN-deficient prostate cancer specimens.

Human V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. ERG protein expression shows almost complete concordance (98.2%) across cribriform and non-cribriform prostatic carcinomas.

  2. ERG (or FLI1 (show FLI1 Proteins) if available) is useful marker for the diagnosis of Phosphaturic mesenchymal tumors.

  3. These results suggested that miR145 might act as a tumor suppressor during the process of colorectal cancer malignant transformation by interacting with ERG.

  4. ERG promotes prostate tumorigenesis together with KDM4A (show KDM4A Proteins) through the upregulation of YAP1 (show YAP1 Proteins). A corollary is that KDM4A (show KDM4A Proteins) as well as YAP1 (show YAP1 Proteins) inhibitors may prove beneficial for the therapy of ERG-overexpressing prostate tumors.

  5. TMPRSS2 (show TMPRSS2 Proteins)-ERG role in prostate cancer invasiveness and regulation of MMP-9 (show MMP9 Proteins) and plexin B1 (show PLXNB1 Proteins).

  6. Our results indicate that it is possible to predict pT3 stage at final histology from TMPRSS2 (show TMPRSS2 Proteins):ERG gene fusion at initial core needle biopsy. FISH determination of TMPRSS2 (show TMPRSS2 Proteins):ERG gene fusion may be particularly useful for patients scheduled to undergo a radical prostatectomy in order to improve oncological and functional results

  7. Data show that significant associations between cyclin-dependent kinase (show CDK1 Proteins) inhibitor p16 upregulation and tumor phenotype or patient prognosis were strictly limited to the subset of transcriptional regulator ERG negative cancers.

  8. Data show there was a good agreement of transcriptional regulator ERG protein (ERG) immunostaining with the presence of TMPRSS2 (show TMPRSS2 Proteins):ERG fusion protein.

  9. Data show a significant association between Alpha-methylacyl-CoA racemase (AMACR (show AMACR Proteins)) and ERG protein with prognostic implication in prostate cancer.

  10. Elucidation of the mechanisms of ERG gene rearrangements and expression promises novel therapeutic and diagnostic avenues for prostate cancer

Zebrafish V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) interaction partners

  1. fli1 (show FLI1 Proteins), and etsrp (show ETV2 Proteins), demonstrated that erg (show KCNH2 Proteins) and fli1 (show FLI1 Proteins) act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin (show CDH5 Proteins)

  2. A combination of gain-of-function and loss-of-function studies suggested a redundant yet specific role for erg (show KCNH2 Proteins) in both angioblast specification/proliferation and early angiogenesis, and a synergistic interaction with the critical ETS (show ETS1 Proteins) factor etsrp (show ETV2 Proteins).

V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) Protein Profile

Protein Summary

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with ERG

  • v-ets erythroblastosis virus E26 oncogene like (LOC100223535)
  • potassium voltage-gated channel, subfamily H (eag-related), member 2 (KCNH2)
  • v-ets erythroblastosis virus E26 oncogene homolog (avian) (ERG)
  • v-ets erythroblastosis virus E26 oncogene homolog (erg-b)
  • v-ets erythroblastosis virus E26 oncogene homolog (erg)
  • avian erythroblastosis virus E-26 (v-ets) oncogene related (Erg)
  • v-ets avian erythroblastosis virus E26 oncogene (Erg)
  • v-ets avian erythroblastosis virus E26 oncogene homolog (ERG)
  • v-ets avian erythroblastosis virus E26 oncogene homolog (erg-a)
  • v-ets erythroblastosis virus E26 oncogene homolog (ERG)
  • v-ets erythroblastosis virus E26 oncogene like (avian) (erg)
  • D030036I24Rik protein
  • erg protein
  • erg-3 protein
  • erg_A protein
  • erg_E protein
  • p55 protein
  • zgc:103429 protein

Protein level used designations for ERG

v-ets erythroblastosis virus E26 oncogene like , Ether-a-go-go-related gene potassium channel 1 , Potassium voltage-gated channel subfamily H member 2 , v-ets erythroblastosis virus E26 oncogene homolog (avian) , v-ets erythroblastosis virus E26 oncogene homolog , erg gene (erg_E) , vascular ETS factor , transcriptional regulator ERG , avian erythroblastosis virus E-26 (v-ets) oncogene related , TMPRSS2/ERG fusion , ets-related , transcriptional regulator ERG (transforming protein ERG) , v-ets avian erythroblastosis virus E26 oncogene related , transcriptional regulator Erg , erg1

GENE ID SPECIES
100223535 Taeniopygia guttata
397334 Sus scrofa
473995 Pan troglodytes
100604101 Nomascus leucogenys
378619 Xenopus laevis
100216056 Xenopus (Silurana) tropicalis
13876 Mus musculus
170909 Rattus norvegicus
2078 Homo sapiens
378618 Xenopus laevis
374146 Gallus gallus
535231 Bos taurus
494073 Danio rerio
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