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VGF Nerve Growth Factor Inducible Proteins (VGF)

VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. Additionally we are shipping VGF Antibodies (93) and VGF Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VGF 7425 O15240
Mouse VGF VGF 381677  
VGF 29461 P20156
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Top VGF Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 16 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

VGF Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Rat (Rattus)

More Proteins for VGF Nerve Growth Factor Inducible (VGF) Interaction Partners

Human VGF Nerve Growth Factor Inducible (VGF) interaction partners

  1. We conclude that some of the already identified variants in VGF from human polymorphism studies may contribute to eating disorders and obesity.

  2. Data show although no any significant differences between patient groups and lean subjects of proteins SYT4 (show SYT4 Proteins), BAG3 (show BAG3 Proteins), APOA1 (show APOA1 Proteins), and VAV3 (show VAV3 Proteins), except for VGF protein, there was a trend between the expression of these four genes and their protein levels.

  3. Data show that two VGF peptides (NAPP-19 and QQET-30) were identified in plasma.

  4. Data indicate an increased number of neurosecretory protein VGF-expressing T cells in patients with Alzheimer's disease (AD) compared to aged healthy controls.

  5. Results indicate that neuron-restrictive silencer factor plays an important role as a repressor of VGF gene regulation in neuroblastoma (show ARHGEF16 Proteins) cells through a mechanism that is dependent on VGF-neuron-restrictive silencer element

  6. NERPs may be potent endogenous suppressors of glucose-dependent insulin (show INS Proteins) secretion.

  7. DISC1 (show DISC1 Proteins) knockdown leads to a reduction of VGF in neurons.

  8. Knock-in mice expressing human VGF were fertile, had increased body weight, whereas those with c-terminal region deletion had reduced adiposity, increased energy expenditure, and improved glucose tolerance.

  9. We conclude that VGF contributes to survival and function of peripheral T cells

  10. Among the 19 genes tested, VGF was found to be completely methylated in several Urothelial Cell Carcinoma cell lines

Mouse (Murine) VGF Nerve Growth Factor Inducible (VGF) interaction partners

  1. results suggest hypothalamic VGF responds to environmental demands and plays an important role in energy balance and glycemic control likely acting in the melanocortin pathway downstream of BDNF (show BDNF Proteins).

  2. Data indicate that high-fat diet induced obese mice showed reduced plasma VGF C-terminus, NAPPE and QQET-like (ERVW) peptide.

  3. VGF expression is regulated by DISC1 (show DISC1 Proteins) through the activation of the PI3K/AKT (show AKT1 Proteins)/CREB (show CREB1 Proteins) pathway.

  4. This study found that VGF expression, both mRNA and protein, was increased 1 h after training in the dorsal hippocampus.

  5. Derived from the C-terminus of VGF, endogenous TLQP-21 peptide contributes to the mechanisms of spinal neuroplasticity after inflammation and nerve injury.

  6. VGF has a role in adrenal large dense core vesicle formation and the regulation of catecholamine levels and blood pressure

  7. These findings reveal that NERP-2 regulates glucose-stimulated insulin (show INS Proteins) secretion by elevating intracellular calcium concentrations.

  8. VGF is regulated by SOD1 (show SOD1 Proteins) and plays a critical role in motor neuron survival

  9. We propose that VGF and/or VGF-derived peptides modulate sympathetic outflow pathways to regulate fat storage and energy expenditure.

  10. Modulation of VGF levels and/or VGF signaling may consequently represent an alternative means to regulate circulating glucose levels and insulin (show INS Proteins) sensitivity.

VGF Protein Profile

Protein Summary

This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.

Gene names and symbols associated with VGF

  • VGF nerve growth factor inducible (VGF)
  • neurosecretory protein VGF-like (LOC618042)
  • VGF nerve growth factor inducible (Vgf)
  • Gm1052 protein
  • VGF protein

Protein level used designations for VGF

VGF nerve growth factor inducible , Neurosecretory protein VGF , neuro-endocrine specific protein VGF , neurosecretory protein VGF , VGF8a protein

463616 Pan troglodytes
100595566 Nomascus leucogenys
618042 Bos taurus
7425 Homo sapiens
381677 Mus musculus
29461 Rattus norvegicus
100687924 Canis lupus familiaris
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