anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Antibodies

VTCN1 encodes a protein belonging to the B7 costimulatory protein family. Additionally we are shipping VTCN1 Proteins (44) and VTCN1 Kits (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VTCN1 242122 Q7TSP5
VTCN1 79679 Q7Z7D3
VTCN1 295322 Q501W4
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Top anti-VTCN1 Antibodies at antibodies-online.com

Showing 10 out of 211 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN334524 (0.3µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Mouse FITC FACS 0.1 mg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of VTCN1 Antibody (Center) in T47D cell line lysates (35 µg/lane). VTCN1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human thyroid carcinoma labeled Anti-B7H4 Polyclonal Antibody, Unconjugated (ABIN671736) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled Anti-B7H4 Polyclonal Antibody, Unconjugated (ABIN671736) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Un-conjugated FACS, IHC (fro), IHC (p) 0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB B7-H4 staining in human lung cancer. Paraffin-embedded human lung cancer tissue is stained with B7-H4 Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$350.00
Details
Mouse Rat Un-conjugated CyTOF, FACS, WB   100 μg Log in to see 8 to 9 Days
$276.15
Details
Human Goat Un-conjugated CyTOF, FACS, WB Detection of Mouse and Human B7-H4 by Western Blot. Western blot shows lysates of mouse placenta tissue, mouse uterus tissue, and SK-BR-3 human breast cancer cell line. PVDF membrane was probed with 2 ug/mL of Goat Anti-Mouse B7-H4 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$372.75
Details
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$340.00
Details

VTCN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-VTCN1 Antibodies

  1. Human Polyclonal VTCN1 Primary Antibody for IHC, ELISA - ABIN1584048 : Basta, Galazka, Mach, Jozwicki, Walentowicz, Wicherek: The immunohistochemical analysis of RCAS1, HLA-G, and B7H4-positive macrophages in partial and complete hydatidiform mole in both applied therapeutic surgery and surgery followed by chemotherapy. in American journal of reproductive immunology (New York, N.Y. : 1989) 2011 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal VTCN1 Primary Antibody for FACS - ABIN2688846 : Sica, Choi, Zhu, Tamada, Wang, Tamura, Chapoval, Flies, Bajorath, Chen: B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. in Immunity 2003 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Polyclonal VTCN1 Primary Antibody for FACS, WB - ABIN4900128 : Lee, Scandiuzzi, Ray, Wei, Hofmeyer, Abadi, Loke, Lin, Yuan, Serreze, Allison, Zang: B7x in the periphery abrogates pancreas-specific damage mediated by self-reactive CD8 T cells. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal VTCN1 Primary Antibody for IHC, IHC (p) - ABIN4282807 : Xu, Zhang, Zhang, Liu, Yin, Liu, Zhuo: Clinical relevance of expression of B7-H1 and B7-H4 in ovarian cancer. in Oncology letters 2016 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal VTCN1 Primary Antibody for CyTOF, FACS - ABIN4900129 : Radichev, Maneva-Radicheva, Amatya, Salehi, Parker, Ellefson, Burn, Savinov: Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal VTCN1 Primary Antibody for FACS - ABIN2477566 : van de Ven, van den Hout, Lindenberg, Sluijter, van Leeuwen, Lougheed, Meijer, van den Tol, Scheper, de Gruijl: Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation. in Blood 2011 (PubMed)

More Antibodies against VTCN1 Interaction Partners

Mouse (Murine) V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) interaction partners

  1. this study shows that B7-H4 knockout hosts mount greater tumor-associated anti-tumor T cell responses and display reduced tumors

  2. Results highlight an importance of VTCN1 stabilization on cell surfaces for the restoration of altered balance of immune control during T1D.

  3. Ablation of B7-H3 (show CD276 Antibodies) but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

  4. B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity.

  5. that B7x can modulate kidney damage in autoimmune diseases including lupus nephritis and anti-glomerular basement membrane disease

  6. B7-H4 can inhibit both antitumor T cells and protumor myeloid-derived suppressor cells (

  7. The endogenous expression of B7-H4 in donor beta cells from transgenic mice prolongs islet allograft survival, confirming the negative role of B7-H4 in regulating alloreactive T-cell responses.

  8. Local overexpression of B7x on pancreatic beta cells is sufficient to abolish CD8 (show CD8A Antibodies) T cell-induced diabetes.

  9. B7-H4 expression may influence the outcome of T-cell tumor cell interactions. Tumor-associated macrophage induced membrane-bound B7-H4 on lung cancer cell represents a novel mechanism by which lung cancer cells evade immune recognition and destruction.

  10. Overexpression of B7-H4 was shown in tumor infiltrated dendritic cells.

Human V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) interaction partners

  1. our study demonstrates a strong promoting role of B7-H4 in lung tumor growth, progression and metastasis

  2. results demonstrated for the first time that miR (show MLXIP Antibodies)-125b-5p could regulate the inflammatory state of macrophages via directly targeting B7-H4

  3. B7-H4 is highly expressed in pancreatic cancer, and is an independent predictor of poor prognosis.

  4. Evidence of associations between genotypes and Juvenile Idiopathic Arthritis were found for VTCN1, while VTCN1_rs2358820 GA was associated with Uveitis .

  5. B7-H4 is highly expressed in human OSCC tissue, and the B7-H4 expression level was associated with the clinicopathological parameters containing pathological grade and lymph node status.

  6. High B7-H4 expression is associated with non-Hodgkin lymphoma.

  7. B7-H4 is frequently expressed in ovarian serous carcinomas, especially high-grade serous carcinomas, and may represent a novel immunotherapeutic target in this cancer.

  8. While PD-L1 (show CD274 Antibodies) expression correlated with MSI (show MSI1 Antibodies) and high grade endometrial tumors, B7-H4 expression was independent of grade, histology and immune cell infiltration.

  9. the present review highlights the therapeutic potential of targeting B7-H4 in cancer

  10. Survival rate of the patients with higher B7-H4 expression was significantly worse than that of the patients with lower B7-H4 expression.

VTCN1 Antigen Profile

Protein Summary

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with VTCN1

  • V-set domain containing T cell activation inhibitor 1 (vtcn1) antibody
  • V-set domain containing T cell activation inhibitor 1 (VTCN1) antibody
  • V-set domain containing T cell activation inhibitor 1 (Vtcn1) antibody
  • B7-H4 antibody
  • B7h.5 antibody
  • B7H4 antibody
  • B7S1 antibody
  • B7X antibody
  • BC032925 antibody
  • PRO1291 antibody
  • RGD1311204 antibody
  • VCTN1 antibody

Protein level used designations for VTCN1

V-set domain-containing T-cell activation inhibitor 1 , V-set domain containing T cell activation inhibitor 1 , V-set domain containing T-cell activation inhibitor 1 , immune costimulatory protein B7-H4 , t cell costimulatory molecule B7x , B7 family member, H4 , B7 superfamily member 1 , T cell costimulatory molecule B7x , T-cell costimulatory molecule B7x

GENE ID SPECIES
379070 Xenopus laevis
418323 Gallus gallus
469433 Pan troglodytes
493551 Xenopus (Silurana) tropicalis
242122 Mus musculus
79679 Homo sapiens
295322 Rattus norvegicus
Selected quality suppliers for anti-VTCN1 (VTCN1) Antibodies
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