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VSIG1 encodes a member of the junctional adhesion molecule (JAM) family. Additionally we are shipping VSIG1 Antibodies (55) and many more products for this protein.
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Study showed that VSIG1 is expressed tissue specifically in both non-cancerous and cancerous tissues, and that VSIG1 has suppressive functions in proliferation, migration, and invasion in cancer cells.
VSIG1 expression was significantly reduced at both the mRNA and protein levels in gastric cancer tissues. loss of VSIG1 expression was significantly correlated with poor overall survival and disease-free survival in gastric cancer patients.
VSIG1 is required for the establishment of glandular versus squamous epithelia in the stomach.
mouse VSIG1 interacts with Sertoli cells by heterophilic adhesion via its first Ig-like domain
This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
V-set and immunoglobulin domain containing 1
, cortical thymocyte marker
, v-set and immunoglobulin domain-containing protein 1-like
, ChT1 thymocyte antigen
, V-set and immunoglobulin domain-containing protein 1
, cell surface A33 antigen
, glycoprotein A34
, cortical thymocyte marker CTX