V-Set and Immunoglobulin Domain-Containing Protein 4 Proteins (VSIG4)

VSIG4 encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. Additionally we are shipping VSIG4 Antibodies (44) and VSIG4 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VSIG4 11326 Q9Y279
VSIG4 278180  
Rat VSIG4 VSIG4 312102  
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Top VSIG4 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human VSIG4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Human Cells Mouse Fc Tag,His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
HOST_Mammalian Cells Human Fc Tag   50 μg Log in to see 4 Days
$269.50
Details
HOST_HEK-293 Cells Human His tag Validation with Western Blot 10 μg Log in to see 12 to 15 Days
$345.35
Details
HOST_Human Human Fc Tag   10 μg Log in to see 15 to 16 Days
$175.00
Details
HOST_Mammalian Cells Mouse His tag   10 μg Log in to see 4 Days
$144.38
Details
HOST_HEK-293 Cells Human Un-conjugated   10 μg Log in to see 2 to 3 Days
$145.00
Details

VSIG4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , ,
Mouse (Murine) ,
,

More Proteins for V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) Interaction Partners

Human V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) interaction partners

  1. The VSIG4 upregulation by LMP1 (show PDLIM7 Proteins) was regulated at the transcriptional level via the NF-kB signaling axis.

  2. VSIG4 expression is significantly upregulated in human masticatory mucosa during wound healing

  3. we concluded that let-7g-5p inhibits epithelial-mesenchymal transition (EMT (show ITK Proteins)) consistent with reduction of glioma stem cell (GSC (show GSC Proteins)) phenotypes by targeting VSIG4 in glioblastoma.

  4. Data indicate that rotein kinase calpha (show PRKACA Proteins) (PKCalpha (show PKCa Proteins)) plays a role in downregulating complement receptor Ig (CRIg coded by V-set and Ig domain-containing protein 4 VSIG4) expression.

  5. complement receptor of the immunoglobulin superfamily-L-factor H (show CFH Proteins) protects glomerular mesangial cells from complement-mediated injury and proliferative lesions

  6. we identified VSIG4 as a potential diagnostic marker of severe preeclampsia. The determination of this gene may improve the prognostic assessment of severe preeclampsia.

  7. Data indicate that massive V-set and Ig domain-containing 4 VSIG4(+) cell infiltration throughout the non-small-cell lung cancer samples.

  8. we showed that a complement receptor of the Ig superfamily (CRIg, also known as Z39Ig), a receptor for complement fragments (C3b and iC3b), was expressed on a subset of intestinal macrophages in murine and human large intestine

  9. These results suggest that T cells can opposite T cell hyporesponsiveness through dampening Z39Ig inhibitory signals from macrophages and thus maintain their anti-viral function in chronic hepatitis B.

  10. Results report the identification and characterization of a Complement Receptor of the Immunoglobulin superfamily, CRIg, that binds complement fragments C3b and iC3b.

Mouse (Murine) V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) interaction partners

  1. These findings reveal a pattern recognition role for CRIg in the direct capture of circulating Gram-positive bacteria from the bloodstream via binding to bacterial teichoic acid.

  2. The macrophage-expressed VSIG4 may act to alleviate renal tubulointerstitial injury via inhibition of T cell infiltration and secretion of inflammation related factors.

  3. complement receptor of the immunoglobulin superfamily-L-factor H (show CFH Proteins) protects glomerular mesangial cells from complement-mediated injury and proliferative lesions

  4. CRIg signals induce anti-intracellular bacterial phagosome activity in a chloride intracellular channel 3 (show CLIC3 Proteins)-dependent manner.

  5. CRIg plays an important role in regulating virus-induced Kupffer cell death and depletion of these cells from the liver sinusoidal lumen

  6. we showed that a complement receptor of the Ig superfamily (CRIg, also known as Z39Ig), a receptor for complement fragments (C3b and iC3b), was expressed on a subset of intestinal macrophages in murine and human large intestine

  7. The interstitial inflammatory cell infiltration and tubular lesion of VSIG4(-/-); urethral obstruction operation mice were increased, with the expression of TGF-beta1 (show TGFB1 Proteins) increased and MMP-2 (show MMP2 Proteins) reduced. VSIG4 may play a role in inhibiting interstitial fibrosis.

  8. Results report the identification and characterization of a Complement Receptor of the Immunoglobulin superfamily, CRIg, that binds complement fragments C3b and iC3b.

  9. The specific expression of VSIG4 on resting macrophages suggests that VSIG4 may be important for the maintenance of T cell unresponsiveness in healthy tissues.

  10. A soluble form of complement receptor of the immunoglobulin superfamily (CRIg) reversed inflammation and bone loss in two experimental models of arthritis by inhibiting the alternative pathway of complement in the joint.

VSIG4 Protein Profile

Protein Summary

This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with VSIG4

  • V-set and immunoglobulin domain containing 4 (VSIG4)
  • V-set and immunoglobulin domain containing 4 (Vsig4)
  • A530061A11 protein
  • BC025105 protein
  • CRIg protein
  • DKFZp468O0322 protein
  • Z39IG protein

Protein level used designations for VSIG4

V-set and immunoglobulin domain containing 4 , V-set and immunoglobulin domain-containing protein 4 , Ig superfamily protein , complement receptor of the immunoglobulin superfamily , protein Z39Ig

GENE ID SPECIES
465677 Pan troglodytes
100171405 Pongo abelii
11326 Homo sapiens
614262 Bos taurus
278180 Mus musculus
312102 Rattus norvegicus
491925 Canis lupus familiaris
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