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Vaccinia Related Kinase 2 Proteins (VRK2)

VRK2 encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. Additionally we are shipping VRK2 Antibodies (49) and VRK2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VRK2 7444 Q86Y07
Mouse VRK2 VRK2 69922 Q8BN21
Rat VRK2 VRK2 360991  
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Top VRK2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   10 μg Log in to see 10 to 12 Days
$434.28
Details

VRK2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Vaccinia Related Kinase 2 (VRK2) Interaction Partners

Human Vaccinia Related Kinase 2 (VRK2) interaction partners

  1. Our data provide preliminary evidence that the VRK2 gene might play a major role in the development of SCZ in the Northwest Chinese Han population.

  2. data may provide evidence for the effect of VRK2 on WM connectivity in patients with schizophrenia

  3. Findings suggest that ubiquitin-specific protease 25 (USP25 (show USP25 Proteins)) as a VRK2 substrate that acts on TRiC (show MARVELD2 Proteins) deubiquitination.

  4. VRK2 is crucial to regulate the ubiquitination-proteosomal degradation of eukaryotic chaperonin TCP-1 ring complex

  5. Data from molecular dynamic simulations suggest that bivalent cations play key structural roles in stabilization of VRK1/VRK2; bivalent cations have no obvious effects on VRK3. These kinases are targets in search for antineoplastic agents. [REVIEW]

  6. Low levels of VRK2A causes an increase in mitochondrial Bax (show BAX Proteins) protein level, leading to an increase in the release of cytochrome C (show CYCS Proteins) and caspase (show CASP3 Proteins) activation, detected by PARP processing.

  7. Generalized epilepsies implicates susceptibility genes: CHRM3 (show CHRM3 Proteins) at 1q43, VRK2 at 2p16.1, ZEB2 at 2q22.3, SCN1A (show SCN1A Proteins) at 2q24.3 and PNPO (show PNPO Proteins) at 17q21.32.

  8. This study analyzed 5 genome-wide supported variants in a Han Chinese sample, and the variant rs2312147 at VRK2 showed significant association, which was confirmed in the meta-analysis combining multiple Asian and European.

  9. Human VRK2 is an active kinase playing a role in regulation of cancer cell invasion through the NFAT (show NFATC1 Proteins) pathway and COX-2 expression.

  10. VRK2A can form a high molecular size complex with both MEK1 (show MAP2K1 Proteins) and KSR1 (show KSR1 Proteins); the KSR1 (show KSR1 Proteins) complex assembled and retained by VRK2A in the endoplasmic reticulum can have a modulatory effect on the signal mediated by MAPK (show MAPK1 Proteins),locally affecting the magnitude of its responses

Mouse (Murine) Vaccinia Related Kinase 2 (VRK2) interaction partners

VRK2 Protein Profile

Protein Summary

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to phosphorylate casein and undergo autophosphorylation. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with VRK2

  • vaccinia related kinase 2 (LOC100345223)
  • vaccinia related kinase 2 (VRK2)
  • vaccinia related kinase 2 (Vrk2)
  • 2810003O05Rik protein
  • AI447698 protein

Protein level used designations for VRK2

vaccinia related kinase 2 , serine/threonine-protein kinase VRK2 , vaccinia virus B1R-related kinase 2 , vaccinia virus BIR kinase related kinase 2 , vaccinia-related kinase 2

GENE ID SPECIES
100345223 Oryctolagus cuniculus
7444 Homo sapiens
69922 Mus musculus
360991 Rattus norvegicus
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