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Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) ELISA Kits

VPS26A belongs to a group of vacuolar protein sorting (VPS) genes. Additionally we are shipping Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Antibodies (45) and Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human VPS26A VPS26A 9559 O75436
Anti-Rat VPS26A VPS26A 361846 Q6AY86
Anti-Mouse VPS26A VPS26A 30930 P40336
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More ELISA Kits for Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Interaction Partners

Human Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) interaction partners

  1. Mutagenesis studies coupled with coimmunoprecipitations revealed that retromer-mediated trafficking requires the Env cytoplasmic tail that we show binds directly to retromer components Vps35 and Vps26.

  2. provides molecular insights into the essential role of Vps26 and Vps35 (show vps35 ELISA Kits) in Rab7 (show RAB7B ELISA Kits)-mediated recruitment of the core retromer complex

  3. This study demonstrated that Genetic variability of VPS26A in parkinsonism.

  4. Mutations in VPS26A are not a frequent cause of Parkinson's disease.

  5. VPS26A binding increases the affinity of the SNX27 (show SNX27 ELISA Kits) PDZ domain (show INADL ELISA Kits) for PDZ (show INADL ELISA Kits)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  6. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function

  7. Colocalization of Vps26 paralogues with different endosomally located Rab (show HRB ELISA Kits) proteins shows prolonged association of Vps26B-retromer with maturing endosomes relative to Vps26A-retromer.

  8. These observations indicate that the mammalian retromer complex assembles by sequential association of SNX1 (show SNX1 ELISA Kits)/2 and Vps26-Vps29 (show VPS29 ELISA Kits)-Vps35 (show vps35 ELISA Kits) subcomplexes on endosomal membranes and that SNX1 (show SNX1 ELISA Kits) and SNX2 (show SNX2 ELISA Kits) play interchangeable but essential roles.

  9. Membrane recruitment of the cargo-selective retromer subcomplex VPS35/29/26 is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5.

Mouse (Murine) Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) interaction partners

  1. VPS26A binding increases the affinity of the SNX27 (show SNX27 ELISA Kits) PDZ domain (show INADL ELISA Kits) for PDZ (show INADL ELISA Kits)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  2. Vps26 is implicated in regulating Vps35p membrane association, therefore Vps26 plays a role in cargo recognition of the cytoplasmic coat retromer complex.

  3. These results revealed that the retromer complex could be formed from different Vps26 isoforms in a tissue-specific manner.

Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Antigen Profile

Antigen Summary

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with VPS26A

  • vacuolar protein sorting 26 homolog A (S. pombe) (VPS26A) antibody
  • vacuolar protein sorting 26 (LOC692917) antibody
  • vacuolar protein sorting homolog26 (vpsh26) antibody
  • vacuolar protein sorting 26 homolog A (S. pombe) (Vps26a) antibody
  • vacuolar protein sorting 26 homolog A (yeast) (Vps26a) antibody
  • vacuolar protein sorting 26A (VPS26A) antibody
  • AA407240 antibody
  • DKFZp459G2011 antibody
  • HB58 antibody
  • Hbeta58 antibody
  • MNC6.7 antibody
  • MNC6_7 antibody
  • PEP8A antibody
  • vacuolar protein sorting 26A antibody
  • Vps26 antibody
  • VPS26A antibody

Protein level used designations for VPS26A

vacuolar protein sorting 26 homolog A (S. pombe) , vacuolar protein sorting-associated protein 26A , vacuolar protein sorting-associated protein 26A-like , vacuolar protein sorting 26 A , vacuolar protein sorting 26 , vacuolar protein sorting homolog26 , zmh1 , 5C06F05 , PCO142195 , p-5C06F05 , PCO142195_ov , uaz5c06f05(gfu) , Zea mouse H58 homolog1 , vesicle protein sorting 26A , H beta 58 , vacuole protein sorting 26 , h58 protein , mVPS26

GENE ID SPECIES
423696 Gallus gallus
461781 Pan troglodytes
479233 Canis lupus familiaris
717371 Macaca mulatta
748846 Pan troglodytes
100174023 Pongo abelii
100385858 Callithrix jacchus
100147400 Equus caballus
100596592 Nomascus leucogenys
692917 Bombyx mori
100282332 Zea mays
510574 Bos taurus
9559 Homo sapiens
361846 Rattus norvegicus
30930 Mus musculus
835435 Arabidopsis thaliana
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