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Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Proteins (VPS26A)

VPS26A belongs to a group of vacuolar protein sorting (VPS) genes. Additionally we are shipping Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VPS26A 9559 O75436
VPS26A 361846 Q6AY86
VPS26A 30930 P40336
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Top Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 56 to 66 Days
$2,803.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,876.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,880.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,880.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

VPS26A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus) ,

Mouse (Murine)

Top referenced Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Proteins

  1. Human VPS26A Protein expressed in Escherichia coli (E. coli) - ABIN1098647 : Gullapalli, Wolfe, Griffin, Magnuson, Trejo: An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins. in Molecular biology of the cell 2006 (PubMed)
    Show all 2 references for ABIN1098647

More Proteins for Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Interaction Partners

Human Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) interaction partners

  1. Mutagenesis studies coupled with coimmunoprecipitations revealed that retromer-mediated trafficking requires the Env cytoplasmic tail that we show binds directly to retromer components Vps35 and Vps26.

  2. provides molecular insights into the essential role of Vps26 and Vps35 (show vps35 Proteins) in Rab7 (show RAB7B Proteins)-mediated recruitment of the core retromer complex

  3. This study demonstrated that Genetic variability of VPS26A in parkinsonism.

  4. Mutations in VPS26A are not a frequent cause of Parkinson's disease.

  5. VPS26A binding increases the affinity of the SNX27 PDZ domain for PDZ- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  6. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function

  7. Colocalization of Vps26 paralogues with different endosomally located Rab (show HRB Proteins) proteins shows prolonged association of Vps26B (show VPS26B Proteins)-retromer with maturing endosomes relative to Vps26A-retromer.

  8. These observations indicate that the mammalian retromer complex assembles by sequential association of SNX1 (show SNX1 Proteins)/2 and Vps26-Vps29 (show VPS29 Proteins)-Vps35 (show vps35 Proteins) subcomplexes on endosomal membranes and that SNX1 (show SNX1 Proteins) and SNX2 (show SNX2 Proteins) play interchangeable but essential roles.

  9. Membrane recruitment of the cargo-selective retromer subcomplex VPS35 (show vps35 Proteins)/29/26 is catalysed by the small GTPase (show RACGAP1 Proteins) Rab7 (show RAB7B Proteins) and inhibited by the Rab (show HRB Proteins)-GAP TBC1D5 (show TBC1D5 Proteins).

Mouse (Murine) Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) interaction partners

  1. VPS26A binding increases the affinity of the SNX27 PDZ domain for PDZ- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  2. Vps26 is implicated in regulating Vps35p membrane association, therefore Vps26 plays a role in cargo recognition of the cytoplasmic coat retromer complex.

  3. These results revealed that the retromer complex could be formed from different Vps26 isoforms in a tissue-specific manner.

Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Protein Profile

Protein Summary

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with VPS26A

  • vacuolar protein sorting 26 homolog A (S. pombe) (VPS26A)
  • vacuolar protein sorting 26 (LOC692917)
  • vacuolar protein sorting homolog26 (vpsh26)
  • vacuolar protein sorting 26 homolog A (S. pombe) (Vps26a)
  • vacuolar protein sorting 26 homolog A (yeast) (Vps26a)
  • vacuolar protein sorting 26A (VPS26A)
  • AA407240 protein
  • DKFZp459G2011 protein
  • HB58 protein
  • Hbeta58 protein
  • MNC6.7 protein
  • MNC6_7 protein
  • PEP8A protein
  • vacuolar protein sorting 26A protein
  • Vps26 protein
  • VPS26A protein

Protein level used designations for VPS26A

vacuolar protein sorting 26 homolog A (S. pombe) , vacuolar protein sorting-associated protein 26A , vacuolar protein sorting-associated protein 26A-like , vacuolar protein sorting 26 A , vacuolar protein sorting 26 , vacuolar protein sorting homolog26 , zmh1 , 5C06F05 , PCO142195 , p-5C06F05 , PCO142195_ov , uaz5c06f05(gfu) , Zea mouse H58 homolog1 , vesicle protein sorting 26A , H beta 58 , vacuole protein sorting 26 , h58 protein , mVPS26

GENE ID SPECIES
423696 Gallus gallus
461781 Pan troglodytes
479233 Canis lupus familiaris
717371 Macaca mulatta
748846 Pan troglodytes
100174023 Pongo abelii
100385858 Callithrix jacchus
100147400 Equus caballus
100596592 Nomascus leucogenys
692917 Bombyx mori
100282332 Zea mays
510574 Bos taurus
9559 Homo sapiens
361846 Rattus norvegicus
30930 Mus musculus
835435 Arabidopsis thaliana
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