anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Antibodies

VPS26A belongs to a group of vacuolar protein sorting (VPS) genes. Additionally we are shipping Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VPS26A 9559 O75436
VPS26A 361846 Q6AY86
VPS26A 30930 P40336
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Top anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of VPS26A Antibody (Center) (ABIN652668) in HepG2 cell line lysates (35 µg/lane). VPS26A (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with VPS26A Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185172 staining (1 ug/ml) of Human Kidney lysate (RIPA buffer, 35 ug total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Goat Un-conjugated ELISA, WB ABIN250155 staining (1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Western Blot: VPS26 Antibody [ABIN250155] - Western blot analysis of VPS26 in Human Kidney lysate using ABIN250155 at 1 ug/ ml. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Chicken Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Rabbit Un-conjugated EIA, WB   0.4 mL Log in to see 12 to 15 Days
$375.38
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample(30 ug whole cell lysate) A:293T B:A431, C:HeLa S3, D:Hep G2 , 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using VPS26, antibody at 1:500 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Cow Goat Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Mouse Rabbit Un-conjugated IHC, WB WB on rat brain lysate using Rabbit antibody to internal region of Vesicle protein sorting 26A (VPS26, VPS26A): whole serum (ABIN351347) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band. 100 μL Log in to see 7 to 8 Days
$454.67
Details

VPS26A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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Rat (Rattus)
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Mouse (Murine)
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Top referenced anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Antibodies

  1. Human Polyclonal VPS26A Primary Antibody for ELISA, WB - ABIN250155 : He, Li, Chang, Tang: GGA proteins mediate the recycling pathway of memapsin 2 (BACE). in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Interaction Partners

Human Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) interaction partners

  1. The retromer complex is a highly conserved membrane trafficking assembly composed of three proteins - Vps26, Vps29 (show VPS29 Antibodies) and Vps35 (show vps35 Antibodies), which are impaired in neurodegenerative diseases. (Review)

  2. X-ray crystallographic analysis of a 4-component complex comprising the VPS26 & VPS35 (show vps35 Antibodies) subunits of retromer, sorting nexin SNX3 (show SNX3 Antibodies), & recycling signal from the divalent cation transporter DMT1 (show DMRT1 Antibodies)-II; analysis identifies a binding site for canonical recycling signals at the interface between VPS26 & SNX3 (show SNX3 Antibodies); shows cooperative interactions among the VPS subunits, SNX3 (show SNX3 Antibodies) & cargo that couple signal-recognition to membrane recruitment.

  3. Mutagenesis studies coupled with coimmunoprecipitations revealed that retromer-mediated trafficking requires the Env cytoplasmic tail that we show binds directly to retromer components Vps35 and Vps26.

  4. provides molecular insights into the essential role of Vps26 and Vps35 (show vps35 Antibodies) in Rab7 (show RAB7B Antibodies)-mediated recruitment of the core retromer complex

  5. This study demonstrated that Genetic variability of VPS26A in parkinsonism.

  6. Mutations in VPS26A are not a frequent cause of Parkinson's disease.

  7. VPS26A binding increases the affinity of the SNX27 (show SNX27 Antibodies) PDZ domain (show INADL Antibodies) for PDZ (show INADL Antibodies)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  8. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function

  9. Colocalization of Vps26 paralogues with different endosomally located Rab (show HRB Antibodies) proteins shows prolonged association of Vps26B (show VPS26B Antibodies)-retromer with maturing endosomes relative to Vps26A-retromer.

  10. These observations indicate that the mammalian retromer complex assembles by sequential association of SNX1 (show SNX1 Antibodies)/2 and Vps26-Vps29 (show VPS29 Antibodies)-Vps35 (show vps35 Antibodies) subcomplexes on endosomal membranes and that SNX1 (show SNX1 Antibodies) and SNX2 (show SNX2 Antibodies) play interchangeable but essential roles.

Mouse (Murine) Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) interaction partners

  1. VPS26A binding increases the affinity of the SNX27 (show SNX27 Antibodies) PDZ domain (show INADL Antibodies) for PDZ (show INADL Antibodies)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  2. Vps26 is implicated in regulating Vps35p membrane association, therefore Vps26 plays a role in cargo recognition of the cytoplasmic coat retromer complex.

  3. These results revealed that the retromer complex could be formed from different Vps26 isoforms in a tissue-specific manner.

Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Antigen Profile

Protein Summary

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with VPS26A

  • VPS26, retromer complex component A (VPS26A) antibody
  • vacuolar protein sorting-associated protein 26A pseudogene (LOC461781) antibody
  • vacuolar protein sorting 26 homolog A (S. pombe) pseudogene (LOC100147400) antibody
  • vacuolar protein sorting 26 (LOC692917) antibody
  • vacuolar protein sorting homolog26 (vpsh26) antibody
  • VPS26 retromer complex component A (Vps26a) antibody
  • vacuolar protein sorting 26A (VPS26A) antibody
  • AA407240 antibody
  • DKFZp459G2011 antibody
  • HB58 antibody
  • Hbeta58 antibody
  • MNC6.7 antibody
  • MNC6_7 antibody
  • PEP8A antibody
  • vacuolar protein sorting 26A antibody
  • Vps26 antibody
  • VPS26A antibody

Protein level used designations for VPS26A

vacuolar protein sorting 26 homolog A (S. pombe) , vacuolar protein sorting-associated protein 26A , vacuolar protein sorting-associated protein 26A-like , vacuolar protein sorting 26 A , vacuolar protein sorting 26 , vacuolar protein sorting homolog26 , zmh1 , 5C06F05 , PCO142195 , p-5C06F05 , PCO142195_ov , uaz5c06f05(gfu) , Zea mouse H58 homolog1 , vesicle protein sorting 26A , H beta 58 , vacuole protein sorting 26 , h58 protein , mVPS26

GENE ID SPECIES
423696 Gallus gallus
461781 Pan troglodytes
479233 Canis lupus familiaris
717371 Macaca mulatta
748846 Pan troglodytes
100174023 Pongo abelii
100385858 Callithrix jacchus
100147400 Equus caballus
100596592 Nomascus leucogenys
692917 Bombyx mori
100282332 Zea mays
510574 Bos taurus
9559 Homo sapiens
361846 Rattus norvegicus
30930 Mus musculus
835435 Arabidopsis thaliana
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