Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae) Proteins (VPS33A)

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Additionally we are shipping VPS33A Antibodies (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VPS33A 65081  
VPS33A 65082 Q96AX1
Mouse VPS33A VPS33A 77573 Q9D2N9
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Top VPS33A Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$554.07
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,719.83
Details

VPS33A Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
, ,

More Proteins for Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae) (VPS33A) Interaction Partners

Human Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae) (VPS33A) interaction partners

  1. Mutations in VPS33A is associated with mucopolysaccharidosis with severe systemic symptoms.

  2. Data suggest that accumulation of autophagosomes confers cytotoxicity in a number of cell types including neurons mimicking neurodegeneration; RNA interference of combinations of MTOR (show FRAP1 Proteins), VPS33A, and STX17 (show STX17 Proteins) lead to accumulation of autophagosomes and cytotoxicity. (MTOR (show FRAP1 Proteins) = mechanistic target of rapamycin (show FRAP1 Proteins) kinase; VPS33A = vacuolar protein sorting 33A; STX17 (show STX17 Proteins) = syntaxin 17 (show STX17 Proteins))

  3. The clinical phenotype and genetic studies support the suggestion that the siblings most probably have a novel disease very likely caused by a VPS33A gene defect.

  4. association of VPS33A with HOPS (show ALPL Proteins) via its interaction with VPS16 (show VPS16 Proteins) is required for both endosome- and autophagosome-lysosome fusion

  5. Melanoma cells depleted of vacuolar protein sorting 33A protein have increased nuclear localization of cis (show CISH Proteins)-diaminedichloroplatinum II, increased nuclear DNA damage by platination, and increased apoptosis, resulting in increased treatment sensitivity.

  6. VPS33A is mutated in Hermansky-Pudlak syndrome and may have a role in melanogenesis

Mouse (Murine) Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae) (VPS33A) interaction partners

  1. VPS33A(D251E) mutation plays dual roles by increasing the HOPS (show TMUB1 Proteins) complex assembly and its association with the autophagic SNARE (show VTI1B Proteins) complex, which selectively affects the autophagosome-lysosome fusion.

  2. VPS33A is mutated in Hermansky-Pudlak syndrome and may have a role in melanogenesis

  3. These studies suggest that loss of Purkinje neurons is the most obvious neurological atrophy in the buff mutant mouse, a structural change that generates motor coordination deficits and impaired postural phenotypes.

  4. Knockdown of Vps33a expression reduced the lysosomal storage of RANKL (show TNFSF11 Proteins) and caused the accumulation of newly synthesized RANKL (show TNFSF11 Proteins) in the Golgi apparatus, indicating that Vps33a is involved in transporting RANKL (show TNFSF11 Proteins) from the Golgi apparatus to secretory lysosomes.

VPS33A Protein Profile

Protein Summary

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.

Gene names and symbols associated with VPS33A

  • VPS33A CORVET/HOPS core subunit (Vps33a)
  • VPS33A, CORVET/HOPS core subunit (VPS33A)
  • vacuolar protein sorting 33 homolog A (S. cerevisiae) (VPS33A)
  • VPS33A, CORVET/HOPS core subunit (vps33a)
  • Vacuolar protein sorting 33A (CGB_E2330C)
  • vacuolar protein sorting 33A (vps33a)
  • VPS33A, CORVET/HOPS core subunit (Vps33a)
  • 3830421M04Rik protein
  • AI503300 protein
  • AW048546 protein
  • AW554476 protein
  • bf protein
  • im:7136893 protein
  • MGC145524 protein
  • r-Vps33a protein
  • vps33a protein
  • wu:fc08g01 protein
  • wu:fc26c10 protein

Protein level used designations for VPS33A

vacuolar protein sorting 33A , vacuolar protein sorting protein 33a , vacuolar protein sorting-associated protein 33A , hVPS33A , vacuolar protein sorting 33 homolog A (S. cerevisiae) , vacuolar protein sorting 33A homolog , vacuolar protein sorting 33A-like , vacuolar protein sorting-associated protein 33A-like , buff , vacuolar sorting protein 33a , vacuolar protein sorting 33 homolog A

GENE ID SPECIES
65081 Rattus norvegicus
65082 Homo sapiens
416861 Gallus gallus
452326 Pan troglodytes
477462 Canis lupus familiaris
510197 Bos taurus
702257 Macaca mulatta
100016452 Monodelphis domestica
100049702 Sus scrofa
100058750 Equus caballus
100074991 Ornithorhynchus anatinus
100220818 Taeniopygia guttata
100344276 Oryctolagus cuniculus
100378976 Saccoglossus kowalevskii
100404193 Callithrix jacchus
100438180 Pongo abelii
100468472 Ailuropoda melanoleuca
100564873 Anolis carolinensis
100605639 Nomascus leucogenys
549689 Xenopus (Silurana) tropicalis
10190275 Cryptococcus gattii WM276
77573 Mus musculus
448942 Danio rerio
100724252 Cavia porcellus
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