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VPS52 encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. Additionally we are shipping VPS52 Antibodies (31) and many more products for this protein.
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The Vps52 was responsible for the tw5 mutation, and revealed development-specific functions of this gene, which was formerly thought to be solely involved in retrograde endocytic transport.
our data indicate that cisplatin resistance in HOCCs is partially attributable to their high expression of p62 (show GTF2H1 Proteins), which plays an important role in preventing ROS (show ROS1 Proteins) stress-induced apoptosis by regulating the Keap1 (show KEAP1 Proteins)-Nrf2 (show GABPA Proteins)-ARE signaling pathway.
Golgi-associated retrograde protein orchestrates retrograde transport from endosomes to the trans-Golgi network by promoting vesicle tethering and assembly of SNARE (show NAPA Proteins) complexes in consecutive, independent steps.[Golgi associated retrograde protein]
Golgi associated retrograde protein complex, consisting of the Vps52, Vps53, and Vps54 proteins, shows significant conservation between various species but diversification and specialization result in important differences in human cells.
Missorting of cathepsin D (show CTSD Proteins) in GARP (show CNGB1 Proteins)-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes.
This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.
, vacuolar protein sorting-associated protein 52 homolog
, SAC2 suppressor of actin mutations 2-like protein